GB9816099D0 - Nicotinamide derivatives and their use as medicaments - Google Patents
Nicotinamide derivatives and their use as medicamentsInfo
- Publication number
- GB9816099D0 GB9816099D0 GBGB9816099.7A GB9816099A GB9816099D0 GB 9816099 D0 GB9816099 D0 GB 9816099D0 GB 9816099 A GB9816099 A GB 9816099A GB 9816099 D0 GB9816099 D0 GB 9816099D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- medicaments
- nicotinamide derivatives
- nicotinamide
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9715584.0A GB9715584D0 (en) | 1997-07-23 | 1997-07-23 | Compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| GB9816099D0 true GB9816099D0 (en) | 1998-09-23 |
| GB2327675A GB2327675A (en) | 1999-02-03 |
| GB2327675A8 GB2327675A8 (en) | 1999-02-25 |
| GB2327675B GB2327675B (en) | 2002-04-24 |
Family
ID=10816363
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9715584.0A Pending GB9715584D0 (en) | 1997-07-23 | 1997-07-23 | Compounds |
| GB9816099A Expired - Fee Related GB2327675B (en) | 1997-07-23 | 1998-07-23 | Nicotinamide derivatives and their use as medicaments |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9715584.0A Pending GB9715584D0 (en) | 1997-07-23 | 1997-07-23 | Compounds |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP3987645B2 (en) |
| GB (2) | GB9715584D0 (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
| MXPA03006885A (en) | 2001-01-31 | 2003-11-13 | Pfizer Prod Inc | Ether derivatives useful as inhibitors of pde4 isozymes. |
| KR20030072614A (en) | 2001-01-31 | 2003-09-15 | 화이자 프로덕츠 인크. | Thiazolyl-, Oxazolyl-, Pyrrolyl-, and Imidazolyl-Acid Amide Derivatives Useful as Inhibitors of PDE4 Isozymes |
| NZ526453A (en) | 2001-01-31 | 2005-01-28 | Pfizer Prod Inc | Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes |
| US7429593B2 (en) | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
| US20040067985A1 (en) * | 2002-10-04 | 2004-04-08 | Fortuna Haviv | Method of inhibiting angiogenesis |
| GB0317472D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
| EP2410043A3 (en) | 2004-12-29 | 2013-01-23 | Hadasit Medical Research Services And Development Ltd. | Stem cells culture systems |
| US8597947B2 (en) | 2004-12-29 | 2013-12-03 | Hadasit Medical Research Services & Development Limited | Undifferentiated stem cell culture systems |
| EP2058310A4 (en) | 2006-09-01 | 2010-11-17 | Kyorin Seiyaku Kk | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor comprising the derivative |
| EP2554661B2 (en) | 2007-04-18 | 2018-02-21 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
| CN101910131B (en) | 2007-11-16 | 2014-04-23 | 里格尔药品股份有限公司 | Carboxamide, sulfonamide and amine compounds and usagmethod thereof |
| EP2231666B1 (en) | 2007-12-12 | 2015-07-29 | Rigel Pharmaceuticals, Inc. | Carboxamide, sulfonamide and amine compounds for metabolic disorders |
| FR2926297B1 (en) | 2008-01-10 | 2013-03-08 | Centre Nat Rech Scient | INHIBITORY CHEMICAL MOLECULES IN THE SPLICE MECHANISM FOR TREATING DISEASES RESULTING FROM SPLICE ANOMALIES. |
| BRPI0911681B8 (en) | 2008-04-23 | 2021-05-25 | Rigel Pharmaceuticals Inc | compound, pharmaceutical composition, and, method of activating the 5'-amp activated protein kinase pathway in a cell in vitro |
| EP2505198A1 (en) | 2011-04-01 | 2012-10-03 | Société Splicos | Compounds for use as therapeutic agents affecting p53 expression and/or activity |
| KR101412794B1 (en) * | 2011-07-27 | 2014-07-01 | 보령제약 주식회사 | New compound, the preparation thereof and the pharmaceutical composition comprising the same for anti-angiogenic drug |
| US11891622B2 (en) | 2014-12-30 | 2024-02-06 | Cell Cure Neurosciences Ltd. | RPE cell populations and methods of generating same |
| ES2880346T3 (en) | 2014-12-30 | 2021-11-24 | Cell Cure Neurosciences Ltd | Evaluation of retinal pigment epithelial cell populations |
| WO2017017686A1 (en) | 2015-07-29 | 2017-02-02 | Hadasit Medical Research Services And Development Ltd. | Large scale production of retinal pigment epithelial cells |
| DK3331994T3 (en) | 2015-08-05 | 2022-11-21 | Cell Cure Neurosciences Ltd | PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS |
| WO2017021972A1 (en) | 2015-08-05 | 2017-02-09 | Cell Cure Neurosciences Ltd. | Preparation of photoreceptors for the treatment of retinal diseases |
| CN108699525A (en) | 2015-10-26 | 2018-10-23 | 细胞治疗神经科学有限公司 | The preparation of retinal pigment epithelium |
| IL269363B2 (en) | 2017-03-16 | 2024-02-01 | Lineage Cell Therapeutics Inc | Methods for measuring therapeutic effects of retinal disease therapies |
| WO2019130061A2 (en) | 2017-12-29 | 2019-07-04 | Cell Cure Neurosciences Ltd. | Retinal pigment epithelium cell compositions |
| WO2020058979A2 (en) | 2018-09-20 | 2020-03-26 | Yeda Research And Development Co. Ltd. | Methods of treating amyotrophic lateral sclerosis |
| EP4351334A1 (en) | 2021-06-09 | 2024-04-17 | Lineage Cell Therapeutics, Inc. | Methods and compositions for treating retinal diseases and conditions |
| WO2023009676A1 (en) | 2021-07-28 | 2023-02-02 | Lineage Cell Therapeutics, Inc. | Expansion of retinal pigment epithelium cells |
| WO2023211857A1 (en) | 2022-04-25 | 2023-11-02 | Lineage Cell Therapeutics, Inc. | Methods and compositions for treating vision loss |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS612667B2 (en) * | 1973-11-20 | 1986-01-27 | Hisamitsu Pharmaceutical Co | |
| JPH01113369A (en) * | 1987-10-23 | 1989-05-02 | Mitsubishi Petrochem Co Ltd | Nicotinic acid amide compound |
| US4861891A (en) * | 1988-08-31 | 1989-08-29 | Pfizer Inc. | Antidepressant N-substituted nicotinamide compounds |
| US5705499A (en) * | 1995-10-06 | 1998-01-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | 8-arylalkyl- and 8-arylheteroalkyl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-e! 1!diazepines and their use in the treatment of HIV-1 infection |
| TW429148B (en) * | 1995-10-27 | 2001-04-11 | Pfizer | Pharmaceutical agents for the treatment of acute and chronic inflammatory diseases |
-
1997
- 1997-07-23 GB GBGB9715584.0A patent/GB9715584D0/en active Pending
-
1998
- 1998-07-23 JP JP24100498A patent/JP3987645B2/en not_active Expired - Fee Related
- 1998-07-23 GB GB9816099A patent/GB2327675B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB2327675A8 (en) | 1999-02-25 |
| GB2327675A (en) | 1999-02-03 |
| JPH11147874A (en) | 1999-06-02 |
| GB2327675B (en) | 2002-04-24 |
| GB9715584D0 (en) | 1997-10-01 |
| JP3987645B2 (en) | 2007-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20110723 |