GB978265A - Method for coating tablets - Google Patents
Method for coating tabletsInfo
- Publication number
- GB978265A GB978265A GB1842761A GB1842761A GB978265A GB 978265 A GB978265 A GB 978265A GB 1842761 A GB1842761 A GB 1842761A GB 1842761 A GB1842761 A GB 1842761A GB 978265 A GB978265 A GB 978265A
- Authority
- GB
- United Kingdom
- Prior art keywords
- copolymers
- weight
- present
- ratio
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- -1 2-hydroxypropoxyl groups Chemical group 0.000 abstract 15
- 239000000203 mixture Substances 0.000 abstract 12
- 229920001577 copolymer Polymers 0.000 abstract 10
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 6
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
- 239000001856 Ethyl cellulose Substances 0.000 abstract 6
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 6
- 229920001249 ethyl cellulose Polymers 0.000 abstract 6
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 6
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 6
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 6
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 6
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 6
- 239000011118 polyvinyl acetate Substances 0.000 abstract 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 4
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 abstract 4
- 239000007859 condensation product Substances 0.000 abstract 4
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 abstract 4
- 239000012530 fluid Substances 0.000 abstract 4
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 abstract 4
- 239000004014 plasticizer Substances 0.000 abstract 4
- 229920001223 polyethylene glycol Polymers 0.000 abstract 4
- 229920000642 polymer Polymers 0.000 abstract 4
- 229920001451 polypropylene glycol Polymers 0.000 abstract 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 4
- 239000001069 triethyl citrate Substances 0.000 abstract 4
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 abstract 4
- 235000013769 triethyl citrate Nutrition 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- PZBLUWVMZMXIKZ-UHFFFAOYSA-N 2-o-(2-ethoxy-2-oxoethyl) 1-o-ethyl benzene-1,2-dicarboxylate Chemical compound CCOC(=O)COC(=O)C1=CC=CC=C1C(=O)OCC PZBLUWVMZMXIKZ-UHFFFAOYSA-N 0.000 abstract 2
- GOJCZVPJCKEBQV-UHFFFAOYSA-N Butyl phthalyl butylglycolate Chemical compound CCCCOC(=O)COC(=O)C1=CC=CC=C1C(=O)OCCCC GOJCZVPJCKEBQV-UHFFFAOYSA-N 0.000 abstract 2
- 229920000623 Cellulose acetate phthalate Polymers 0.000 abstract 2
- 229920008347 Cellulose acetate propionate Polymers 0.000 abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Natural products C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Natural products CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 2
- UGZICOVULPINFH-UHFFFAOYSA-N acetic acid;butanoic acid Chemical compound CC(O)=O.CCCC(O)=O UGZICOVULPINFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000005250 alkyl acrylate group Chemical group 0.000 abstract 2
- 239000003125 aqueous solvent Substances 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 229920006217 cellulose acetate butyrate Polymers 0.000 abstract 2
- 229940081734 cellulose acetate phthalate Drugs 0.000 abstract 2
- YYXLGGIKSIZHSF-UHFFFAOYSA-N ethene;furan-2,5-dione Chemical group C=C.O=C1OC(=O)C=C1 YYXLGGIKSIZHSF-UHFFFAOYSA-N 0.000 abstract 2
- 229940116333 ethyl lactate Drugs 0.000 abstract 2
- 229920001038 ethylene copolymer Polymers 0.000 abstract 2
- 235000011187 glycerol Nutrition 0.000 abstract 2
- 229960001047 methyl salicylate Drugs 0.000 abstract 2
- 229920001983 poloxamer Polymers 0.000 abstract 2
- 235000019448 polyvinylpyrrolidone-vinyl acetate copolymer Nutrition 0.000 abstract 2
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 abstract 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- AVMNFQHJOOYCAP-UHFFFAOYSA-N acetic acid;propanoic acid Chemical compound CC(O)=O.CCC(O)=O AVMNFQHJOOYCAP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3251660A | 1960-05-31 | 1960-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB978265A true GB978265A (en) | 1964-12-23 |
Family
ID=21865338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1842761A Expired GB978265A (en) | 1960-05-31 | 1961-05-19 | Method for coating tablets |
Country Status (3)
| Country | Link |
|---|---|
| ES (1) | ES267539A1 (enExample) |
| GB (1) | GB978265A (enExample) |
| NL (1) | NL265304A (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50160418A (enExample) * | 1974-06-24 | 1975-12-25 | ||
| US4155993A (en) | 1977-01-13 | 1979-05-22 | Lipha, Lyonnaise Industrielle Pharmaceutique | Prolonged-release pharmaceutical compositions for oral administration, their methods of making and use |
| AT396330B (de) * | 1985-06-24 | 1993-08-25 | Ciba Geigy Ag | Verfahren zur herstellung einer festen haltbaren darreichungsform |
| US5651984A (en) * | 1992-08-04 | 1997-07-29 | Eurand America, Incorporated | Controlled release potassium tablet |
| US7632521B2 (en) | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
| AT513519A1 (de) * | 2012-10-23 | 2014-05-15 | Gebro Holding Gmbh | Filmbeschichtungszusammensetzung |
-
0
- NL NL265304D patent/NL265304A/xx unknown
-
1961
- 1961-05-19 GB GB1842761A patent/GB978265A/en not_active Expired
- 1961-05-20 ES ES0267539A patent/ES267539A1/es not_active Expired
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50160418A (enExample) * | 1974-06-24 | 1975-12-25 | ||
| US4155993A (en) | 1977-01-13 | 1979-05-22 | Lipha, Lyonnaise Industrielle Pharmaceutique | Prolonged-release pharmaceutical compositions for oral administration, their methods of making and use |
| AT396330B (de) * | 1985-06-24 | 1993-08-25 | Ciba Geigy Ag | Verfahren zur herstellung einer festen haltbaren darreichungsform |
| US5651984A (en) * | 1992-08-04 | 1997-07-29 | Eurand America, Incorporated | Controlled release potassium tablet |
| US7632521B2 (en) | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
| AT513519A1 (de) * | 2012-10-23 | 2014-05-15 | Gebro Holding Gmbh | Filmbeschichtungszusammensetzung |
Also Published As
| Publication number | Publication date |
|---|---|
| ES267539A1 (es) | 1961-11-16 |
| NL265304A (enExample) |
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