GB977214A - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB977214A
GB977214A GB37557/62A GB3755762A GB977214A GB 977214 A GB977214 A GB 977214A GB 37557/62 A GB37557/62 A GB 37557/62A GB 3755762 A GB3755762 A GB 3755762A GB 977214 A GB977214 A GB 977214A
Authority
GB
United Kingdom
Prior art keywords
bismuth
pectinate
pharmaceutical
aqueous
cosmetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB37557/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR875377A external-priority patent/FR1660M/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB977214A publication Critical patent/GB977214A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/94—Bismuth compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof

Abstract

The invention comprises bismuth pectinate and aqueous gels or suspensions thereof. The compound may be prepared by treating pectin, preferably in aqueous solution, with an aqueous solution of a bismuth salt, e.g. bismuth, nitrate or subnitrate, thereby precipitating bismuth pectinate as an aqueous gel. The reaction is preferably effected in presence of an inhibitor for hydrolysis of bismuth salts, e.g. glycerol or nitric acid. The nitric acid, if used, is more than 1, and less than 3 times the concentration of elementary bismuth in the reaction mixture. The aqueous gel of bismuth pectinate may be dehydrated by washing with, e.g. ethanol or acetone, to yield a powder, which is insoluble in water and organic solvents but soluble in dilute acids. The bismuth pectinate, containing e.g. 10-30% by weight of bismuth, may be used in pharmaceutical and cosmetic preparations (see Division A5).ALSO:Pharmaceutical and cosmetic compositions contain bismuth pectinate (a bismuth salt of pectin) (Division C3). For therapeutic use, e.g. in treatment of gastro-intestinal ailments, the bismuth pectinate composition may contain pharmaceutical carriers, excipients or other physiologically active substances, and may be in the form of e.g. powders, syrups or elixers. Granulates may be prepared in which the bismuth pectinate is associated with sugar, gums, dyestuffs or perfumes. For peroral administration, e.g. in sachets, as stomach and intestinal adsorbants and protectors, the preferred dosage unit is 0.5 to 10 g. Bismuth pectinate may also be formulated as gels, colloidal suspensions, milks or creams, containing also mineral salts and wetting agents, mucilages, gelatines or glycerol. Bismuth pectinate disperses in strong electrolytic solutions to form non-greasy cosmetic creams.
GB37557/62A 1961-10-09 1962-10-04 Chemical compounds Expired GB977214A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR875377A FR1660M (en) 1961-10-09 1961-10-09 Medicinal product for the treatment of gastrointestinal disorders, based on bismuth pectate.
FR904635A FR1438167A (en) 1961-10-09 1962-07-20 New pectin derivatives and their preparation process

Publications (1)

Publication Number Publication Date
GB977214A true GB977214A (en) 1964-12-02

Family

ID=26192613

Family Applications (1)

Application Number Title Priority Date Filing Date
GB37557/62A Expired GB977214A (en) 1961-10-09 1962-10-04 Chemical compounds

Country Status (6)

Country Link
US (1) US3306819A (en)
BE (1) BE623354A (en)
DE (1) DE1192635B (en)
FR (1) FR1438167A (en)
GB (1) GB977214A (en)
NL (2) NL130132C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111217937A (en) * 2020-03-25 2020-06-02 山西振东安特生物制药有限公司 Method for preparing colloidal bismuth pectin

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128874C (en) * 1965-07-01
CA853195A (en) * 1968-09-30 1970-10-06 Abitibi Paper Company Ltd. Wet strength additive system
US4184974A (en) * 1974-05-16 1980-01-22 Leuven James W Van Liquid biocidal compositions comprising a mixture of silver ions and sodium pectate
US4267168A (en) * 1977-03-11 1981-05-12 Aquatain Partnership Method of reducing bacteria on human tissue using liquid biocidal compositions comprising a mixture of silver ions and sodium pectate
US4289758A (en) * 1979-09-17 1981-09-15 Aquatain Partnership Liquid biocidal compositions compriing a mixture of silver ions and sodium pectate
CN104116721B (en) * 2014-08-08 2016-06-29 严白双 A kind of Couoidal bismuth pectin capsules agent and preparation technology thereof
CN106038584A (en) * 2016-05-27 2016-10-26 郑州思辩科技有限公司 Colloidal bismuth pectin capsule preparation and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2259767A (en) * 1939-07-15 1941-10-21 Sardik Inc Food product
US2373729A (en) * 1942-12-05 1945-04-17 Claude R Wickard Thickening and congealing agent
US2416176A (en) * 1944-02-14 1947-02-18 African Sisal & Produce Compan Process for the treatment of plant flesh and the recovery of pectic products therefrom
US2448818A (en) * 1945-09-14 1948-09-07 Us Agriculture Process of isolating low-methoxyl pectinic acids
US2550705A (en) * 1946-11-12 1951-05-01 William D Maclay Method for obtaining pectinic acids of low methyl ester content in concentrated form
US2802773A (en) * 1953-10-19 1957-08-13 Reheis Company Inc Basic aluminum carbonate and glycine composition and method of making same
DE1099129B (en) * 1958-09-10 1961-02-09 Thomae Gmbh Dr K Skin care products

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111217937A (en) * 2020-03-25 2020-06-02 山西振东安特生物制药有限公司 Method for preparing colloidal bismuth pectin

Also Published As

Publication number Publication date
NL283828A (en)
US3306819A (en) 1967-02-28
DE1192635B (en) 1965-05-13
FR1438167A (en) 1966-05-13
BE623354A (en)
NL130132C (en)

Similar Documents

Publication Publication Date Title
DE3438455A1 (en) L-LYSINE AND L-HISTIDINE PYRUVATE
PT71727A (en) Process for preparing a pharmaceutical composition particularly suitable for cancer treatment
ES417377A1 (en) Salt of S-adenosil-L-methionine and process of preparation
EP0024096B1 (en) Complexes of bivalent copper, methods of preparation thereof and compositions containing said complexes
GB977214A (en) Chemical compounds
US3275643A (en) Allantoin-pantothenate compounds
US2113374A (en) Salicylic acid derivatives
US2761867A (en) Aluminum salts of allantoin and their preparation and compositions comprising the same
US3608086A (en) Treatment of dermatologic diseases employing aluminum propionate aluminum dipropionate and certain double acid salts thereof
GB1388330A (en) Method of preparing stable aqueous solutions of organosilicic compounds and the resulting products and applications thereof
EP0030023A3 (en) A heterocyclic compound and its synthesis, pharmaceutical formulations thereof and the use of the compounds and the formulations in medicine
JPS5562014A (en) Aqueous poultice having no skin irritation effect
GB1011719A (en) Basic bismuth salt and preparation thereof
CA1254517A (en) Pharmaceutical compositions containing 1,8-dihydroxy-10-phenyl-9-anthrone as an active ingredient
DE2104851A1 (en)
JPS6396123A (en) Phologistic agent containing vitamin a acid zinc salt
US3222253A (en) Antimitotic colchicines
US3262847A (en) Calcium salt of dextran for treating cattle delivery paresis
ES8501760A1 (en) Pyrrolidinone derivatives, their preparation and pharmaceutical compositions containing them.
GB1578977A (en) Salts of aliphatic-thioethylamines
US3637837A (en) Gamma-alkylthiolysines
US3519638A (en) 4,5-diphenylimidazole derivative
RU2118161C1 (en) Antiinflammatory agent
US3743739A (en) Pharmaceutical compositions containing 1-benzoyl-3,5-dimethyl pyrazole in the treatment of inflammation
US3342675A (en) 2, 4, 5-trichlorophenol-lower-alkylamine reaction products as skin germicides