GB975795A - Microtome - Google Patents

Microtome

Info

Publication number
GB975795A
GB975795A GB38957/62A GB3895762A GB975795A GB 975795 A GB975795 A GB 975795A GB 38957/62 A GB38957/62 A GB 38957/62A GB 3895762 A GB3895762 A GB 3895762A GB 975795 A GB975795 A GB 975795A
Authority
GB
United Kingdom
Prior art keywords
knife
junctions
projection
plate
cooling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB38957/62A
Inventor
Ernest Robert Shandon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C Reichert Optische Werke AG
Original Assignee
C Reichert Optische Werke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C Reichert Optische Werke AG filed Critical C Reichert Optische Werke AG
Priority to GB38957/62A priority Critical patent/GB975795A/en
Priority to US312957A priority patent/US3220290A/en
Priority to DES87862A priority patent/DE1216567B/en
Publication of GB975795A publication Critical patent/GB975795A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G01N2001/061—Blade details
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T83/00—Cutting
    • Y10T83/283—With means to control or modify temperature of apparatus or work
    • Y10T83/293—Of tool

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

975,795. Microtomes. C. REICHERT OPTISCHE WERKE A.G. Sept. 26, 1963 [Oct. 15, 1962], No. 38957/62. Heading G2J. In a microtome wherein the knife 12, Fig. 1, is held by the projections 14 of a pair of jaws 7, 8 of a clamp 6 held together by screws 11, each projection 14 is provided with a cooling unit. As shown, Fig. 3, the knife 12 is contacted on each side by a plate 23 of silver, copper aluminium or other material of good heat conductivity having loaded to its opposite side a set of peltier cooling junctions 15. A set of peltier heating junctions 17, connected by semiconductor elements 20 to the junctions 15, are bonded to one face of a good heatconducting plate 123 whose opposite face is cooled by water flowing through inlet 21, chamber 18 and outlet 22. A thermistor 24 allows measurement of the temperature of the knife for indication or control. In a modification, Fig. 5, not shown, one projection 14 at each end of the knife 12 is provided with a reservoir through which a cooling fluid may be passed or into which liquid air may be admitted.
GB38957/62A 1962-10-15 1962-10-15 Microtome Expired GB975795A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB38957/62A GB975795A (en) 1962-10-15 1962-10-15 Microtome
US312957A US3220290A (en) 1962-10-15 1963-10-01 Microtome knife clamp with knife cooling means
DES87862A DE1216567B (en) 1962-10-15 1963-10-15 Knife holder for microtomes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB38957/62A GB975795A (en) 1962-10-15 1962-10-15 Microtome

Publications (1)

Publication Number Publication Date
GB975795A true GB975795A (en) 1964-11-18

Family

ID=10406735

Family Applications (1)

Application Number Title Priority Date Filing Date
GB38957/62A Expired GB975795A (en) 1962-10-15 1962-10-15 Microtome

Country Status (3)

Country Link
US (1) US3220290A (en)
DE (1) DE1216567B (en)
GB (1) GB975795A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2145240A (en) * 1983-07-30 1985-03-20 Parke Davis & Co Clamping device for a cutter of a microtome
GB2151368A (en) * 1983-07-30 1985-07-17 Parke Davis & Co Clamping mechanism for a cutter of a microtome

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296821A (en) * 1965-05-05 1967-01-10 Malinin Theodore Microtome including freezing attachments
GB1130222A (en) * 1965-11-03 1968-10-09 Rue Frigistor Ltd De Microtome apparatus
US3447594A (en) * 1967-04-19 1969-06-03 Edgar Harold Andrews Temperature control for an ultra microtome
GB1350881A (en) * 1970-04-07 1974-04-24 Nat Res Dev Microtomes
DE7921193U1 (en) * 1979-07-25 1981-01-22 Ernst Leitz Wetzlar Gmbh, 6330 Wetzlar HANDLE FOR SWIVELING MACHINE PARTS
US4262567A (en) * 1979-10-01 1981-04-21 Bettin Elizabeth M Device for cooling microtome blade
US4395075A (en) * 1982-03-24 1983-07-26 E. I. Du Pont De Nemours & Co. Misalignment system for a microtome
US4502358A (en) * 1982-06-16 1985-03-05 Parke, Davis & Company Knife holder for sliding microtomes
AU3323695A (en) * 1994-08-09 1996-03-07 Edison Materials Technology Center, The Cryogenic machining
DE19640044A1 (en) * 1996-09-30 1998-04-02 Microm Laborgeraete Gmbh Cryostat microtome
DE202005019765U1 (en) * 2005-12-17 2006-02-16 Leica Microsystems Nussloch Gmbh Microtome with a cooling device
DE102010016728B4 (en) * 2010-04-30 2011-11-24 Leica Biosystems Nussloch Gmbh RM CoolClamp with an air duct for dissipating the heat of a cooling element and microtome
US11353380B2 (en) * 2014-09-23 2022-06-07 Shabbir Bambot Apparatus for faster pathology

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1246327A (en) * 1917-01-08 1917-11-13 Eugene Rusterholz Fabric-cutting machine.
US2232008A (en) * 1939-01-20 1941-02-18 Spencer Lens Co Microtome blade holder
US2439671A (en) * 1944-02-16 1948-04-13 Harvey N Ott Knife holder for microtomes
US2680992A (en) * 1949-08-08 1954-06-15 Roussel Uclaf Apparatus for slicing organic tissue
US2643579A (en) * 1950-02-21 1953-06-30 Jr George W Jacoby Microtome knife
US2629230A (en) * 1950-07-28 1953-02-24 Maurice J Bishko Refrigerated table for microtomes
US2901944A (en) * 1957-08-22 1959-09-01 American Optical Corp Knife holder clamp for microtome
US2991628A (en) * 1959-09-15 1961-07-11 Gen Motors Corp Refrigerating apparatus
US3137184A (en) * 1961-07-05 1964-06-16 Peter G Meyers Tool cooling apparatus
US3091939A (en) * 1961-10-02 1963-06-04 Allis Chalmers Mfg Co Thermoelectric cooler circuit with thermal electric feed-back arrangement
US3093135A (en) * 1962-01-29 1963-06-11 Max L Hirschhorn Cooled surgical instrument

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2145240A (en) * 1983-07-30 1985-03-20 Parke Davis & Co Clamping device for a cutter of a microtome
GB2151368A (en) * 1983-07-30 1985-07-17 Parke Davis & Co Clamping mechanism for a cutter of a microtome

Also Published As

Publication number Publication date
US3220290A (en) 1965-11-30
DE1216567B (en) 1966-05-12

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