GB975291A - Derivatives of 1-phenyl-2-aminoethanol - Google Patents
Derivatives of 1-phenyl-2-aminoethanolInfo
- Publication number
- GB975291A GB975291A GB34894/62A GB3489462A GB975291A GB 975291 A GB975291 A GB 975291A GB 34894/62 A GB34894/62 A GB 34894/62A GB 3489462 A GB3489462 A GB 3489462A GB 975291 A GB975291 A GB 975291A
- Authority
- GB
- United Kingdom
- Prior art keywords
- eto
- compounds
- meo
- ethoxy
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical class NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 4
- -1 alphamethylbenzyl Chemical group 0.000 abstract 3
- UAOMVDZJSHZZME-UHFFFAOYSA-N diisopropylamine Chemical compound CC(C)NC(C)C UAOMVDZJSHZZME-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- OJUGVDODNPJEEC-UHFFFAOYSA-N phenylglyoxal Chemical compound O=CC(=O)C1=CC=CC=C1 OJUGVDODNPJEEC-UHFFFAOYSA-N 0.000 abstract 3
- 239000012279 sodium borohydride Substances 0.000 abstract 3
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 3
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HQABUPZFAYXKJW-UHFFFAOYSA-N butan-1-amine Chemical compound CCCCN HQABUPZFAYXKJW-UHFFFAOYSA-N 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 2
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 2
- VKCYHJWLYTUGCC-UHFFFAOYSA-N nonan-2-one Chemical compound CCCCCCCC(C)=O VKCYHJWLYTUGCC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 2
- GOHROFKFPXJARU-UHFFFAOYSA-N 1-(3,4-diethoxyphenyl)-2-hydroxyiminopropan-1-one Chemical compound ON=C(C)C(=O)C1=CC(=C(C=C1)OCC)OCC GOHROFKFPXJARU-UHFFFAOYSA-N 0.000 abstract 1
- UOHYHQFGIQIJTO-UHFFFAOYSA-N 2-(4-ethoxy-3-nitrophenyl)oxirane Chemical compound C(C)OC1=C(C=C(C=C1)C1CO1)[N+](=O)[O-] UOHYHQFGIQIJTO-UHFFFAOYSA-N 0.000 abstract 1
- GGSZMSUCAONREI-UHFFFAOYSA-N 2-amino-1-(3,4-diethoxyphenyl)propan-1-ol Chemical compound CCOC1=CC=C(C(O)C(C)N)C=C1OCC GGSZMSUCAONREI-UHFFFAOYSA-N 0.000 abstract 1
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 abstract 1
- OXJWAYFWYRCUMJ-UHFFFAOYSA-N 2-bromo-1-(4-ethoxy-3-nitrophenyl)ethanol Chemical compound C(C)OC1=C(C=C(C=C1)C(CBr)O)[N+](=O)[O-] OXJWAYFWYRCUMJ-UHFFFAOYSA-N 0.000 abstract 1
- QQEQMZAWCWQSFX-UHFFFAOYSA-N 2-bromo-1-(4-ethoxy-3-nitrophenyl)ethanone Chemical compound CCOC1=CC=C(C(=O)CBr)C=C1[N+]([O-])=O QQEQMZAWCWQSFX-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium on carbon Substances [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 1
- 229910018162 SeO2 Inorganic materials 0.000 abstract 1
- 150000008062 acetophenones Chemical class 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 230000031709 bromination Effects 0.000 abstract 1
- 238000005893 bromination reaction Methods 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 229940043279 diisopropylamine Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000007429 general method Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- LIGACIXOYTUXAW-UHFFFAOYSA-N phenacyl bromide Chemical compound BrCC(=O)C1=CC=CC=C1 LIGACIXOYTUXAW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- JPJALAQPGMAKDF-UHFFFAOYSA-N selenium dioxide Chemical compound O=[Se]=O JPJALAQPGMAKDF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK441664AA DK104466C (da) | 1962-09-12 | 1963-09-10 | Fremgangsmåde til fremstilling af 1-phenyl-2-alkylaminoethanolderivater eller syreadditionssalte deraf. |
| DK441564AA DK105277C (da) | 1962-09-12 | 1963-09-10 | Fremgangsmåde til fremstilling af 1-phenyl-2-alkylaminoalkanolderivater eller syreadditionssalte deraf. |
| DK441464AA DK106041C (da) | 1962-09-12 | 1963-09-10 | Fremgangsmåde til fremstilling af 1-phenyl-2-alkylaminoalkanolderivater eller syreadditionssalte deraf. |
| DK427163AA DK104465C (da) | 1962-09-12 | 1963-09-10 | Fremgangsmåde til fremstilling af 1-phenyl-2-alkylaminoalkanolderivater eller syreadditionssalte deraf. |
| FR956840A FR3077M (fr) | 1962-09-12 | 1963-12-11 | Médicaments nouveaux a base de dérivés benzéniques pour le traitement de maladies des arteres coronaires. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR988029A FR3877M (fr) | 1964-09-14 | 1964-09-14 | Nouveaux sels aminés basiques pour le traitement des états de carence protidique. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB975291A true GB975291A (en) | 1964-11-11 |
Family
ID=8838299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB34894/62A Expired GB975291A (en) | 1962-09-12 | 1962-09-12 | Derivatives of 1-phenyl-2-aminoethanol |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE637333A (enrdf_load_stackoverflow) |
| FR (1) | FR3877M (enrdf_load_stackoverflow) |
| GB (1) | GB975291A (enrdf_load_stackoverflow) |
| NL (1) | NL297595A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115465853A (zh) * | 2022-09-07 | 2022-12-13 | 西华大学 | 一种基于柠檬酸和手性2-氨基-1,2-二苯基乙醇橙光碳点及其制备方法与应用 |
-
0
- NL NL297595D patent/NL297595A/xx unknown
- BE BE637333D patent/BE637333A/xx unknown
-
1962
- 1962-09-12 GB GB34894/62A patent/GB975291A/en not_active Expired
-
1964
- 1964-09-14 FR FR988029A patent/FR3877M/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115465853A (zh) * | 2022-09-07 | 2022-12-13 | 西华大学 | 一种基于柠檬酸和手性2-氨基-1,2-二苯基乙醇橙光碳点及其制备方法与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL297595A (enrdf_load_stackoverflow) | |
| BE637333A (enrdf_load_stackoverflow) | |
| FR3877M (fr) | 1966-01-31 |
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