GB970439A - Pyridopyrimidinone compounds - Google Patents
Pyridopyrimidinone compoundsInfo
- Publication number
- GB970439A GB970439A GB29421/62A GB2942162A GB970439A GB 970439 A GB970439 A GB 970439A GB 29421/62 A GB29421/62 A GB 29421/62A GB 2942162 A GB2942162 A GB 2942162A GB 970439 A GB970439 A GB 970439A
- Authority
- GB
- United Kingdom
- Prior art keywords
- secondary amino
- compounds
- alkyl
- pyrido
- pyrimidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention comprises 4H-pyrido-[1, 2-a] pyrimidin-4-ones substituted in the 2-position by a secondary amino radical through a lower alkoxylene residue, optionally substituted in the 3-position by an alkyl, cycloalkyl, phenyl or phenalkyl group containing up to and including 13 carbon atoms, the 3-position substituent and the pyridine ring being further substituted by groups such as alkyl, alkoxy, trifluoromethyl or by halogen atoms, and their acid addition salts, and the preparation thereof by condensing a 2-aminopyridine with a di-lower alkyl malonic ester and alkylating the resultant 4H-pyrido [1, 2-a]-hydroxy-pyrimidin-4-one with a secondary amino lower alkyl halide. "Lower" indicates 1-5 carbon atoms in the groups so described and a "secondary amino" group is one wherein attachment of a hydrogen atom to the unsatisfied valence of the radical would produce a secondary amine. Pharmaceutical compositions comprise the compounds of the invention together with a carrier. The compounds are analeptics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13619461A | 1961-09-06 | 1961-09-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB970439A true GB970439A (en) | 1964-09-23 |
Family
ID=22471759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29421/62A Expired GB970439A (en) | 1961-09-06 | 1962-07-31 | Pyridopyrimidinone compounds |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE621702A (en) |
| FR (1) | FR2201M (en) |
| GB (1) | GB970439A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960863A (en) | 1974-06-25 | 1976-06-01 | Sankyo Company Limited | Pyrido[1,2-a]pyrimidinone derivatives |
| AU4231293A (en) * | 1992-05-13 | 1993-12-13 | E.I. Du Pont De Nemours And Company | Substituted pyrido(1,2-A)pyrimidinone derivatives as fungicides |
-
1962
- 1962-07-31 GB GB29421/62A patent/GB970439A/en not_active Expired
- 1962-08-24 BE BE621702A patent/BE621702A/en unknown
- 1962-11-20 FR FR915917A patent/FR2201M/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BE621702A (en) | 1962-12-17 |
| FR2201M (en) | 1963-12-09 |
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