GB970439A - Pyridopyrimidinone compounds - Google Patents

Pyridopyrimidinone compounds

Info

Publication number
GB970439A
GB970439A GB29421/62A GB2942162A GB970439A GB 970439 A GB970439 A GB 970439A GB 29421/62 A GB29421/62 A GB 29421/62A GB 2942162 A GB2942162 A GB 2942162A GB 970439 A GB970439 A GB 970439A
Authority
GB
United Kingdom
Prior art keywords
secondary amino
compounds
alkyl
pyrido
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB29421/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Cutter Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cutter Laboratories Inc filed Critical Cutter Laboratories Inc
Publication of GB970439A publication Critical patent/GB970439A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention comprises 4H-pyrido-[1, 2-a] pyrimidin-4-ones substituted in the 2-position by a secondary amino radical through a lower alkoxylene residue, optionally substituted in the 3-position by an alkyl, cycloalkyl, phenyl or phenalkyl group containing up to and including 13 carbon atoms, the 3-position substituent and the pyridine ring being further substituted by groups such as alkyl, alkoxy, trifluoromethyl or by halogen atoms, and their acid addition salts, and the preparation thereof by condensing a 2-aminopyridine with a di-lower alkyl malonic ester and alkylating the resultant 4H-pyrido [1, 2-a]-hydroxy-pyrimidin-4-one with a secondary amino lower alkyl halide. "Lower" indicates 1-5 carbon atoms in the groups so described and a "secondary amino" group is one wherein attachment of a hydrogen atom to the unsatisfied valence of the radical would produce a secondary amine. Pharmaceutical compositions comprise the compounds of the invention together with a carrier. The compounds are analeptics.
GB29421/62A 1961-09-06 1962-07-31 Pyridopyrimidinone compounds Expired GB970439A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13619461A 1961-09-06 1961-09-06

Publications (1)

Publication Number Publication Date
GB970439A true GB970439A (en) 1964-09-23

Family

ID=22471759

Family Applications (1)

Application Number Title Priority Date Filing Date
GB29421/62A Expired GB970439A (en) 1961-09-06 1962-07-31 Pyridopyrimidinone compounds

Country Status (3)

Country Link
BE (1) BE621702A (en)
FR (1) FR2201M (en)
GB (1) GB970439A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960863A (en) 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
EP0640083A1 (en) * 1992-05-13 1995-03-01 E.I. Du Pont De Nemours And Company Substituted pyrido 1,2-a]pyrimidinone derivatives as fungicides

Also Published As

Publication number Publication date
BE621702A (en) 1962-12-17
FR2201M (en) 1963-12-09

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