GB968805A - Benzene-sulphonyl semicarbazides - Google Patents

Benzene-sulphonyl semicarbazides

Info

Publication number
GB968805A
GB968805A GB1365363A GB1365363A GB968805A GB 968805 A GB968805 A GB 968805A GB 1365363 A GB1365363 A GB 1365363A GB 1365363 A GB1365363 A GB 1365363A GB 968805 A GB968805 A GB 968805A
Authority
GB
United Kingdom
Prior art keywords
group
alkyl
formula
amino group
benzenesulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1365363A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB968805A publication Critical patent/GB968805A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises benzenesulphonyl semicarbazides of the formula: <FORM:0968805/C1/1> and salts thereof, wherein X is a halogen atom or an alkyl or alkoxy radical (e.g. methyl or methoxy) and R1 and R2 are alkyl, alkenyl, cycloalkyl or cycloalkyl-alkyl radicals or R1 and R2 together with the nitrogen atom form a heterocyclic ring containing 3-8 cyclic carbon atoms, optionally bearing alkyl substituents and optionally containing a further hetero atom (e.g. pyperidine and pyrrolidine); together with processes for their preparation by reacting a benzenesulphonyl compound of the formula: <FORM:0968805/C1/2> with a compound of the formula B-N(R1)R2 wherein W is an amino group or a group convertible to amine by reduction or hydrolysis, one of the residues A and B is an amino group and the other is an isocyanate group or a group which is converted to isocyanate under the reaction conditions, followed if necessary by conversion of W into an amino group. The products are used pharmaceutically as oral anti-diabetic agents.
GB1365363A 1962-04-06 1963-04-05 Benzene-sulphonyl semicarbazides Expired GB968805A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB66696A DE1168415B (en) 1962-04-06 1962-04-06 Process for the preparation of new benzenesulfonyl semicarbazides

Publications (1)

Publication Number Publication Date
GB968805A true GB968805A (en) 1964-09-02

Family

ID=6975237

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1365363A Expired GB968805A (en) 1962-04-06 1963-04-05 Benzene-sulphonyl semicarbazides

Country Status (5)

Country Link
AT (1) AT242708B (en)
CH (1) CH448049A (en)
DE (1) DE1168415B (en)
DK (1) DK113495B (en)
GB (1) GB968805A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017140778A1 (en) * 2016-02-16 2017-08-24 The University Of Queensland Sulfonylureas and related compounds and use of same
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017140778A1 (en) * 2016-02-16 2017-08-24 The University Of Queensland Sulfonylureas and related compounds and use of same
CN109071454A (en) * 2016-02-16 2018-12-21 昆士兰大学 Sulfonylureas and related compound and application thereof
CN109071454B (en) * 2016-02-16 2023-02-17 昆士兰大学 Sulfonylureas and related compounds and uses thereof
US11858922B2 (en) 2016-02-16 2024-01-02 The University Of Queensland Sulfonylureas and related compounds and use of same
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses

Also Published As

Publication number Publication date
DE1168415B (en) 1964-04-23
AT242708B (en) 1965-10-11
CH448049A (en) 1967-12-15
DK113495B (en) 1969-03-31

Similar Documents

Publication Publication Date Title
NL980043I1 (en) Quinoline intermediates for the synthesis of 1H-imidazoc4,5-quinolines and 1H-imidazoc4,5-quinoline-4-amine.
SE8104781L (en) Heterocyclic Associations
NO870944D0 (en) PROCEDURE FOR THE PREPARATION OF HETEROARYL OXY-BETA CARBOLIN DERIVATIVES.
ES466366A1 (en) Meta-sulfonamido-benzamides
SE7501365L (en)
HUT38648A (en) Process for producing beta-lactam antibiotica and pharmaceutical, growth-controlling and antioxidative compositions
HUT43067A (en) Process for preparing phenoxy-substituted beta-carboline derivatives further pharmaceutical compositions containing such compounds
GB968805A (en) Benzene-sulphonyl semicarbazides
GB1045534A (en) New 1-benzyl-5,6-dialkoxy benzimidazoles and a process for their manufacture
GB1019784A (en) New benzene-sulphonyl-semicarbazides
NZ240272A (en) Piperazine derivatives; pharmaceutical compositions and preparatory processes
SE7812371L (en) PROCEDURE FOR PREPARING PHENOXIAL CANOLAMINE DERIVATIVES
DK48188A (en) ERGOLINYL-HETEROCYCLIC COMPOUNDS AND PROCEDURES FOR PREPARING THEREOF
HUT43068A (en) Process for preparing 5-amino-alkyl-beta-carboline derivatives and pharmaceutical compositions containing them
GB1079224A (en) Process for the production of pyridazinone derivatives
GB1108060A (en) Indole derivatives and a process for their production
GB810304A (en) Improvements in or relating to amines
GB1072167A (en) Improvements in or relating to oxa-1-azabicycloalkane derivatives
GB852971A (en) New n-substituted camphidine derivatives and processes for their preparation
GB878600A (en) Thiopyrimidine derivatives
ES351012A1 (en) Method and intermediates for producing indole derivatives
GB1032251A (en) Piperazine compounds and their preparation
GB1005028A (en) Novel 1:4-benzodioxan derivatives
GB1027025A (en) Benzothiadiazine derivatives
GB1019112A (en) Process for the production of pyridazone derivatives and pyridazone derivatives produced by said process