GB966098A - Barbiturate derivatives - Google Patents
Barbiturate derivativesInfo
- Publication number
- GB966098A GB966098A GB39718/59A GB3971859A GB966098A GB 966098 A GB966098 A GB 966098A GB 39718/59 A GB39718/59 A GB 39718/59A GB 3971859 A GB3971859 A GB 3971859A GB 966098 A GB966098 A GB 966098A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- compounds
- formula
- halogen atom
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical class O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 10
- 125000005843 halogen group Chemical group 0.000 abstract 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- -1 aliphatic hydrocarbon radicals Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000003944 halohydrins Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001338 aliphatic hydrocarbons Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- 238000006471 dimerization reaction Methods 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39718/59A GB966098A (en) | 1959-11-23 | 1959-11-23 | Barbiturate derivatives |
| DK457860AA DK104062C (da) | 1959-11-23 | 1960-11-18 | Fremgangsmåde til fremstilling af barbitursyreforbindelser. |
| CH1303460A CH405321A (de) | 1959-11-23 | 1960-11-21 | Verfahren zur Herstellung von Barbitursäurederivaten |
| ES0262653A ES262653A1 (es) | 1959-11-23 | 1960-11-22 | Un procedimiento para la preparaciën de compuestos terapeuticos |
| BE597345A BE597345A (fr) | 1959-11-23 | 1960-11-22 | Dérivés de l'acide barbiturique et leur préparation. |
| FR853586A FR995M (enrdf_load_stackoverflow) | 1959-11-23 | 1961-02-22 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB39718/59A GB966098A (en) | 1959-11-23 | 1959-11-23 | Barbiturate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB966098A true GB966098A (en) | 1964-08-06 |
Family
ID=10411094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB39718/59A Expired GB966098A (en) | 1959-11-23 | 1959-11-23 | Barbiturate derivatives |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE597345A (enrdf_load_stackoverflow) |
| CH (1) | CH405321A (enrdf_load_stackoverflow) |
| DK (1) | DK104062C (enrdf_load_stackoverflow) |
| ES (1) | ES262653A1 (enrdf_load_stackoverflow) |
| FR (1) | FR995M (enrdf_load_stackoverflow) |
| GB (1) | GB966098A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US7723346B2 (en) | 2000-07-26 | 2010-05-25 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US7776871B2 (en) | 2002-12-11 | 2010-08-17 | Taro Pharmaceutical Industries Ltd. | Method of treating movement disorders using barbituric acid derivatives |
-
1959
- 1959-11-23 GB GB39718/59A patent/GB966098A/en not_active Expired
-
1960
- 1960-11-18 DK DK457860AA patent/DK104062C/da active
- 1960-11-21 CH CH1303460A patent/CH405321A/de unknown
- 1960-11-22 ES ES0262653A patent/ES262653A1/es not_active Expired
- 1960-11-22 BE BE597345A patent/BE597345A/fr unknown
-
1961
- 1961-02-22 FR FR853586A patent/FR995M/fr active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683071B2 (en) | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US7723346B2 (en) | 2000-07-26 | 2010-05-25 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US8076346B2 (en) | 2000-07-26 | 2011-12-13 | Taro Pharamaceutical Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
| US8158639B2 (en) | 2000-07-26 | 2012-04-17 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
| US7776871B2 (en) | 2002-12-11 | 2010-08-17 | Taro Pharmaceutical Industries Ltd. | Method of treating movement disorders using barbituric acid derivatives |
| US8314115B2 (en) | 2002-12-11 | 2012-11-20 | Taro Pharmaceutical Industries Limited | Method of treating movement disorders using barbituric acid derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| ES262653A1 (es) | 1961-06-01 |
| DK104062C (da) | 1966-03-28 |
| BE597345A (fr) | 1961-03-15 |
| FR995M (enrdf_load_stackoverflow) | 1961-12-11 |
| CH405321A (de) | 1966-01-15 |
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