GB9613718D0 - Thrombin inhibitors - Google Patents

Thrombin inhibitors

Info

Publication number
GB9613718D0
GB9613718D0 GBGB9613718.7A GB9613718A GB9613718D0 GB 9613718 D0 GB9613718 D0 GB 9613718D0 GB 9613718 A GB9613718 A GB 9613718A GB 9613718 D0 GB9613718 D0 GB 9613718D0
Authority
GB
United Kingdom
Prior art keywords
thrombin inhibitors
thrombin
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9613718.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thrombosis Research Institute
Original Assignee
Thrombosis Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombosis Research Institute filed Critical Thrombosis Research Institute
Priority to GBGB9613718.7A priority Critical patent/GB9613718D0/en
Publication of GB9613718D0 publication Critical patent/GB9613718D0/en
Priority to PCT/GB1997/001575 priority patent/WO1998000443A1/fr
Priority to JP10503898A priority patent/JP2000516203A/ja
Priority to AU30426/97A priority patent/AU3042697A/en
Priority to EP97925198A priority patent/EP0910583A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
GBGB9613718.7A 1996-06-29 1996-06-29 Thrombin inhibitors Pending GB9613718D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB9613718.7A GB9613718D0 (en) 1996-06-29 1996-06-29 Thrombin inhibitors
PCT/GB1997/001575 WO1998000443A1 (fr) 1996-06-29 1997-06-11 Inhibiteurs de thrombine
JP10503898A JP2000516203A (ja) 1996-06-29 1997-06-11 トロンビン阻害剤
AU30426/97A AU3042697A (en) 1996-06-29 1997-06-11 Thrombin inhibitors
EP97925198A EP0910583A1 (fr) 1996-06-29 1997-06-11 Inhibiteurs de thrombine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9613718.7A GB9613718D0 (en) 1996-06-29 1996-06-29 Thrombin inhibitors

Publications (1)

Publication Number Publication Date
GB9613718D0 true GB9613718D0 (en) 1996-08-28

Family

ID=10796126

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9613718.7A Pending GB9613718D0 (en) 1996-06-29 1996-06-29 Thrombin inhibitors

Country Status (5)

Country Link
EP (1) EP0910583A1 (fr)
JP (1) JP2000516203A (fr)
AU (1) AU3042697A (fr)
GB (1) GB9613718D0 (fr)
WO (1) WO1998000443A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112572B2 (en) 2002-09-09 2006-09-26 Trigen Limited Multivalent metal salts of boronic acids
DK1400245T3 (da) * 2002-09-09 2006-08-28 Trigen Ltd Borsyresalte anvendelige til parenterale formuleringer til selektiv thrombininhibering
US20070022556A1 (en) * 2005-07-28 2007-02-01 Walworth Van T Wind deflector with symmetrical geometry
GB0711779D0 (en) 2007-06-18 2007-07-25 Univ Singapore Thrombin inhibitor
RU2353619C2 (ru) * 2007-06-28 2009-04-27 Общество С Ограниченной Ответственностью "Бионика" Новые соединения, обладающие функцией антикоагулянтов, фармацевтические композиции на их основе для лечения тромботических состояний и плазмозамещающий раствор для коррекции гиперкоагуляционных нарушений при гемодилюции
US9518128B2 (en) 2011-12-14 2016-12-13 Janssen Pharmaceuticals, Inc. Thrombin-binding antibody molecules
GB201121513D0 (en) 2011-12-14 2012-01-25 Cambridge Entpr Ltd Thrombin-binding antibody molecules and uses thereof
WO2019030706A1 (fr) 2017-08-10 2019-02-14 Janssen Pharmaceutica Nv Molécules d'anticorps anti-thrombine et méthodes d'utilisation en chirurgie orthopédique
WO2019035055A1 (fr) 2017-08-16 2019-02-21 Janssen Pharmaceutica Nv Molécules d'anticorps anti-thrombine et procédés d'utilisation avec des agents antiagrégants plaquettaires

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
US6060451A (en) * 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
GB9506212D0 (en) * 1995-03-27 1995-05-17 Iaf Biochem Int Bifunctional thrombin inhibitors bearing highly truncated fibrinogen recognition exosite binding component

Also Published As

Publication number Publication date
WO1998000443A1 (fr) 1998-01-08
EP0910583A1 (fr) 1999-04-28
JP2000516203A (ja) 2000-12-05
AU3042697A (en) 1998-01-21

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