GB9603314D0 - Immunogenic detoxified mutant toxins - Google Patents

Immunogenic detoxified mutant toxins

Info

Publication number
GB9603314D0
GB9603314D0 GBGB9603314.7A GB9603314A GB9603314D0 GB 9603314 D0 GB9603314 D0 GB 9603314D0 GB 9603314 A GB9603314 A GB 9603314A GB 9603314 D0 GB9603314 D0 GB 9603314D0
Authority
GB
United Kingdom
Prior art keywords
mutant toxins
detoxified mutant
immunogenic detoxified
immunogenic
toxins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9603314.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines SRL
Original Assignee
Biocine SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocine SpA filed Critical Biocine SpA
Priority to GBGB9603314.7A priority Critical patent/GB9603314D0/en
Publication of GB9603314D0 publication Critical patent/GB9603314D0/en
Priority to EP97902552A priority patent/EP0880361A1/en
Priority to CA002244800A priority patent/CA2244800A1/en
Priority to JP9529153A priority patent/JP2000506002A/ja
Priority to PCT/IB1997/000183 priority patent/WO1997029771A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1239—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Vibrionaceae (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
GBGB9603314.7A 1996-02-16 1996-02-16 Immunogenic detoxified mutant toxins Pending GB9603314D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB9603314.7A GB9603314D0 (en) 1996-02-16 1996-02-16 Immunogenic detoxified mutant toxins
EP97902552A EP0880361A1 (en) 1996-02-16 1997-02-17 Immunogenic detoxified mutants of cholera toxin
CA002244800A CA2244800A1 (en) 1996-02-16 1997-02-17 Immunogenic detoxified mutants of cholera toxin
JP9529153A JP2000506002A (ja) 1996-02-16 1997-02-17 コレラトキシンの免疫原性無毒化変異体
PCT/IB1997/000183 WO1997029771A1 (en) 1996-02-16 1997-02-17 Immunogenic detoxified mutants of cholera toxin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9603314.7A GB9603314D0 (en) 1996-02-16 1996-02-16 Immunogenic detoxified mutant toxins

Publications (1)

Publication Number Publication Date
GB9603314D0 true GB9603314D0 (en) 1996-04-17

Family

ID=10788903

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9603314.7A Pending GB9603314D0 (en) 1996-02-16 1996-02-16 Immunogenic detoxified mutant toxins

Country Status (5)

Country Link
EP (1) EP0880361A1 (ja)
JP (1) JP2000506002A (ja)
CA (1) CA2244800A1 (ja)
GB (1) GB9603314D0 (ja)
WO (1) WO1997029771A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045324A1 (en) * 1997-04-04 1998-10-15 The Uab Research Foundation Use of cholera toxin mutants as mucosal adjuvants
US7393630B2 (en) 1997-12-16 2008-07-01 Novartis Vaccines And Diagnostics, Inc. Use of microparticles combined with submicron oil-in-water emulsions
PT1042001E (pt) * 1997-12-16 2002-09-30 Chiron Corp Uso de microparticulas combinadas com emulsoes submicronicas oleo-em-agua
IL142231A0 (en) * 1998-09-30 2002-03-10 American Cyanamid Co Mutant cholera holotoxin as an adjuvant
US7384640B1 (en) 1999-09-30 2008-06-10 Wyeth Holdings Corporation Mutant cholera holotoxin as an adjuvant
ATE494908T1 (de) 1999-10-26 2011-01-15 Novartis Vaccines & Diagnostic Pflanzen lektine als mukosale adjuvantien
ATE451386T1 (de) 2001-06-07 2009-12-15 Wyeth Corp Mutantenformen von cholera holotoxin als adjuvans
WO2002098369A2 (en) * 2001-06-07 2002-12-12 Wyeth Holdings Corporation Mutant forms of cholera holotoxin as an adjuvant
WO2007047749A1 (en) 2005-10-18 2007-04-26 Novartis Vaccines And Diagnostics Inc. Mucosal and systemic immunizations with alphavirus replicon particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101715A (en) * 1991-05-02 2005-06-19 Amgen Inc Recombinant dna-derived cholera toxin subunit analogs
IT1253009B (it) * 1991-12-31 1995-07-10 Sclavo Ricerca S R L Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
GB9513371D0 (en) * 1995-06-30 1995-09-06 Biocine Spa Immunogenic detoxified mutant toxins
GB9326174D0 (en) * 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant

Also Published As

Publication number Publication date
EP0880361A1 (en) 1998-12-02
WO1997029771A1 (en) 1997-08-21
CA2244800A1 (en) 1997-08-21
JP2000506002A (ja) 2000-05-23

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