GB9514451D0 - Sustained-release formulation - Google Patents

Sustained-release formulation

Info

Publication number
GB9514451D0
GB9514451D0 GBGB9514451.5A GB9514451A GB9514451D0 GB 9514451 D0 GB9514451 D0 GB 9514451D0 GB 9514451 A GB9514451 A GB 9514451A GB 9514451 D0 GB9514451 D0 GB 9514451D0
Authority
GB
United Kingdom
Prior art keywords
sustained
release formulation
threo
methylphenidate
subject invention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9514451.5A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chirotech Technology Ltd
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Priority to GBGB9514451.5A priority Critical patent/GB9514451D0/en
Publication of GB9514451D0 publication Critical patent/GB9514451D0/en
Priority to CZ9892A priority patent/CZ285956B6/cs
Priority to PCT/GB1996/001690 priority patent/WO1997003673A1/en
Priority to KR10-1998-0700286A priority patent/KR100481416B1/ko
Priority to DE69623970T priority patent/DE69623970T2/de
Priority to EP96924083A priority patent/EP0841928B1/en
Priority to CA002223643A priority patent/CA2223643C/en
Priority to AU64661/96A priority patent/AU702371B2/en
Priority to SK29-98A priority patent/SK281569B6/sk
Priority to HU9802252A priority patent/HU224314B1/hu
Priority to DK96924083T priority patent/DK0841928T3/da
Priority to PT96924083T priority patent/PT841928E/pt
Priority to US08/679,875 priority patent/US5874090A/en
Priority to ES96924083T priority patent/ES2186790T3/es
Priority to JP9506412A priority patent/JPH11509228A/ja
Priority to AT96924083T priority patent/ATE224715T1/de
Priority to MX9800394A priority patent/MX9800394A/es
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
GBGB9514451.5A 1995-07-14 1995-07-14 Sustained-release formulation Pending GB9514451D0 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GBGB9514451.5A GB9514451D0 (en) 1995-07-14 1995-07-14 Sustained-release formulation
AT96924083T ATE224715T1 (de) 1995-07-14 1996-07-15 Formulierung von d-threo methylphenidat mit verzögerter freisetzung
SK29-98A SK281569B6 (sk) 1995-07-14 1996-07-15 Prípravok s predĺženým uvoľňovaním obsahujúci metylfenidát
DK96924083T DK0841928T3 (da) 1995-07-14 1996-07-15 Sustained release-formulering af d-threo-methylphenidat
KR10-1998-0700286A KR100481416B1 (ko) 1995-07-14 1996-07-15 디-트레오-메틸페니데이트의지속적인방출제형물
DE69623970T DE69623970T2 (de) 1995-07-14 1996-07-15 Formulierung von d-threo methylphenidat mit verzögerter freisetzung
EP96924083A EP0841928B1 (en) 1995-07-14 1996-07-15 Sustained-release formulation of d-threo-methylphenidate
CA002223643A CA2223643C (en) 1995-07-14 1996-07-15 Sustained-release formulation of d-threo-methylphenidate
AU64661/96A AU702371B2 (en) 1995-07-14 1996-07-15 Sustained-release formulation of D-threo-methylphenidate
CZ9892A CZ285956B6 (cs) 1995-07-14 1996-07-15 Prostředek trvale uvolňující D-treomethylfenidát
HU9802252A HU224314B1 (hu) 1995-07-14 1996-07-15 D-treo-metil-fenidátot tartalmazó, késleltetett hatóanyag-felszabadítású készítmény
PCT/GB1996/001690 WO1997003673A1 (en) 1995-07-14 1996-07-15 Sustained-release formulation of d-threo-methylphenidate
PT96924083T PT841928E (pt) 1995-07-14 1996-07-15 Formulacao de libertacao prolongada de d-trep-metilfenidato
US08/679,875 US5874090A (en) 1995-07-14 1996-07-15 Sustained-release formulation of methylphenidate
ES96924083T ES2186790T3 (es) 1995-07-14 1996-07-15 Formulacion de d-treo-metilfenidato de liberacion prolongada.
JP9506412A JPH11509228A (ja) 1995-07-14 1996-07-15 D−トレオ−メチルフェニデートの持効性剤型
MX9800394A MX9800394A (es) 1995-07-14 1998-01-13 Formulacion de liberacion sostenida de d-treo-metilfenidato.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9514451.5A GB9514451D0 (en) 1995-07-14 1995-07-14 Sustained-release formulation

Publications (1)

Publication Number Publication Date
GB9514451D0 true GB9514451D0 (en) 1995-09-13

Family

ID=10777685

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9514451.5A Pending GB9514451D0 (en) 1995-07-14 1995-07-14 Sustained-release formulation

Country Status (17)

Country Link
US (1) US5874090A (https=)
EP (1) EP0841928B1 (https=)
JP (1) JPH11509228A (https=)
KR (1) KR100481416B1 (https=)
AT (1) ATE224715T1 (https=)
AU (1) AU702371B2 (https=)
CA (1) CA2223643C (https=)
CZ (1) CZ285956B6 (https=)
DE (1) DE69623970T2 (https=)
DK (1) DK0841928T3 (https=)
ES (1) ES2186790T3 (https=)
GB (1) GB9514451D0 (https=)
HU (1) HU224314B1 (https=)
MX (1) MX9800394A (https=)
PT (1) PT841928E (https=)
SK (1) SK281569B6 (https=)
WO (1) WO1997003673A1 (https=)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
WO1997003671A1 (en) 1995-07-14 1997-02-06 Medeva Europe Limited Composition comprising d-threo-methylphenidate and another drug
US7081238B2 (en) * 1995-11-03 2006-07-25 The President And Fellows Of Harvard College Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
US20020102291A1 (en) * 1997-12-15 2002-08-01 Noven Pharmaceuticals, Inc. Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
US20010055613A1 (en) 1998-10-21 2001-12-27 Beth A. Burnside Oral pulsed dose drug delivery system
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
EP1126826B3 (en) 1998-11-02 2019-05-15 Alkermes Pharma Ireland Limited Multiparticulate modified release composition of methylphenidate
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
US6419960B1 (en) 1998-12-17 2002-07-16 Euro-Celtique S.A. Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
US6673367B1 (en) * 1998-12-17 2004-01-06 Euro-Celtique, S.A. Controlled/modified release oral methylphenidate formulations
US7083808B2 (en) 1998-12-17 2006-08-01 Euro-Celtique S.A. Controlled/modified release oral methylphenidate formulations
US6395752B1 (en) * 1999-03-04 2002-05-28 Pharmaquest Limited Method of treating depression using 1-threo-methylphenidate
US6127385A (en) * 1999-03-04 2000-10-03 Pharmaquest Limited Method of treating depression using l-threo-methylphenidate
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
EP1165054A4 (en) * 1999-04-06 2005-02-09 Pharmaquest Ltd PHARMACEUTICAL DOSAGE FORM FOR INTERMITTENT DELIVERY OF METHYLPHENIDATE
US7553478B2 (en) * 1999-05-12 2009-06-30 President And Fellows Of Harvard College Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level
GB9913458D0 (en) * 1999-06-09 1999-08-11 Medeva Europ Ltd The therapeutic use of d-threo-methylphenidate
US20100143248A1 (en) * 1999-06-28 2010-06-10 President And Fellows Of Harvard College Methods for diagnosing and monitoring treatment of adhd by assessing the dopamine transporter level
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
AU764453B2 (en) 1999-10-29 2003-08-21 Euro-Celtique S.A. Controlled release hydrocodone formulations
JP3856283B2 (ja) * 2000-02-14 2006-12-13 シャープ株式会社 固体撮像装置および撮像装置の駆動方法
US6221883B1 (en) * 2000-04-12 2001-04-24 Ross Baldessarini Method of dopamine inhibition using l-threo-methylphenidate
EP1163907B1 (en) * 2000-06-17 2006-04-12 Pharmaquest Limited Use of l-threo-methylphenidate for the manufacture of a medicament for the treatment of depression
US7674480B2 (en) * 2000-06-23 2010-03-09 Teva Pharmaceutical Industries Ltd. Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
US20020187192A1 (en) * 2001-04-30 2002-12-12 Yatindra Joshi Pharmaceutical composition which reduces or eliminates drug abuse potential
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20030049272A1 (en) * 2001-08-30 2003-03-13 Yatindra Joshi Pharmaceutical composition which produces irritation
US6638533B2 (en) 2002-01-03 2003-10-28 George Krsek Pulse dosage formulations of methylphenidate and method to prepare same
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
US7988993B2 (en) * 2002-12-09 2011-08-02 Andrx Pharmaceuticals, Inc. Oral controlled release dosage form
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
CA2591247A1 (en) * 2004-12-09 2006-06-15 Celgene Corporation Treatment of patients suffering from a disease having a family history or diagnosis of tics or tourette's syndrome with d-threo methylphenidate
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
AU2006235483B2 (en) * 2005-04-12 2010-11-25 Elan Pharma International Limited Controlled release compositions comprising a cephalosporin for the treatment of a bacterial infection
WO2007037790A2 (en) * 2005-06-08 2007-04-05 Elan Corporation, Plc Modified release famciclovir compositions
CN102488652B (zh) 2006-03-16 2014-06-18 特瑞斯制药股份有限公司 含有药物-离子交换树脂复合物的经修饰释放的制剂
US8846100B2 (en) 2006-05-12 2014-09-30 Shire Llc Controlled dose drug delivery system
US8709477B2 (en) * 2009-08-13 2014-04-29 Kremers Urban Pharmaceuticals, Inc` Pharmaceutical dosage form
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
US8287903B2 (en) 2011-02-15 2012-10-16 Tris Pharma Inc Orally effective methylphenidate extended release powder and aqueous suspension product
US9603809B2 (en) 2011-03-23 2017-03-28 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US8916588B2 (en) 2011-03-23 2014-12-23 Ironshore Pharmaceuticals & Development, Inc. Methods for treatment of attention deficit hyperactivity disorder
US9283214B2 (en) 2011-03-23 2016-03-15 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US9119809B2 (en) 2011-03-23 2015-09-01 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US10292937B2 (en) 2011-03-23 2019-05-21 Ironshore Pharmaceuticals & Development, Inc. Methods of treatment of attention deficit hyperactivity disorder
US9498447B2 (en) 2011-03-23 2016-11-22 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
DK3272342T3 (da) 2011-03-23 2021-06-07 Ironshore Pharmaceuticals & Dev Inc Fremgangsmåder og sammensætninger til behandling af opmærksomhedsforstyrrelse
US11241391B2 (en) 2011-03-23 2022-02-08 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US10905652B2 (en) 2011-03-23 2021-02-02 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
US8927010B2 (en) 2011-03-23 2015-01-06 Ironshore Pharmaceuticals & Development, Inc. Compositions for treatment of attention deficit hyperactivity disorder
CA2880456A1 (en) 2012-08-15 2014-02-20 Tris Pharma, Inc. Methylphenidate extended release chewable tablet
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
US12458592B1 (en) 2017-09-24 2025-11-04 Tris Pharma, Inc. Extended release amphetamine tablets
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
KR102174787B1 (ko) 2018-11-14 2020-11-05 호서대학교 산학협력단 재사용이 가능한 다용도 로드 및 이를 갖는 약물 투여기
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2507631A (en) * 1944-01-19 1950-05-16 Ciba Pharm Prod Inc Pyridine and piperidine compounds and process of making same
US2957880A (en) * 1953-12-23 1960-10-25 Ciba Pharm Prod Inc Process for the conversion of stereoisomers
US2838519A (en) * 1953-12-23 1958-06-10 Ciba Pharm Prod Inc Process for the conversion of stereoisomers
US4192827A (en) * 1974-06-27 1980-03-11 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders

Also Published As

Publication number Publication date
DE69623970D1 (de) 2002-10-31
SK281569B6 (sk) 2001-05-10
EP0841928A1 (en) 1998-05-20
DE69623970T2 (de) 2003-06-05
KR19990028984A (ko) 1999-04-15
HU224314B1 (hu) 2005-07-28
AU702371B2 (en) 1999-02-18
JPH11509228A (ja) 1999-08-17
HUP9802252A3 (en) 1999-04-28
DK0841928T3 (da) 2003-01-27
KR100481416B1 (ko) 2005-07-29
EP0841928B1 (en) 2002-09-25
CA2223643A1 (en) 1997-02-06
AU6466196A (en) 1997-02-18
HUP9802252A2 (hu) 1999-01-28
CZ285956B6 (cs) 1999-12-15
WO1997003673A1 (en) 1997-02-06
ES2186790T3 (es) 2003-05-16
ATE224715T1 (de) 2002-10-15
MX9800394A (es) 1998-09-30
PT841928E (pt) 2002-12-31
SK2998A3 (en) 1998-07-08
CZ9298A3 (cs) 1998-06-17
CA2223643C (en) 2003-12-23
US5874090A (en) 1999-02-23

Similar Documents

Publication Publication Date Title
GB9514451D0 (en) Sustained-release formulation
ZA955466B (en) Stereochemical wortmannin derivatives
HUP9603081A3 (en) Process for the preparation of bis(silyl-alkyl)-disulfides
BG101966A (en) Application of 1l-agonist for the treatment of lack of urine retention
NO974378D0 (no) Fremgangsmåte til behandling av gasser
ZA968957B (en) Process for the preparation of dihaloazolopyrimidines.
EP0651650A4 (en) METHOD FOR TREATING EYE DISEASES BY MEANS OF TGF - g (b).
HUP9900110A3 (en) Novel process for the synthesis of omeprazole
GR3032521T3 (en) Process for the hydrogenation of imines
BG103649A (en) Method for the preparation of eprosartan
ZA976854B (en) Treatment of psychotic disorders.
BG103650A (en) Method for the preparation of eprosartan
PL322279A1 (en) Method of obtaining 1,2-benzoylthiazolin-3-ones
IL118200A0 (en) Process for the preparation of substituted 2-fluoro-pyrimidines
ZA96897B (en) Methods of inhibiting effects of IL-6.
IL118788A0 (en) Process for the hydrogenation of imines
EP0383937A4 (en) Process for treating by-product oil
ZA949564B (en) Method for treating constipation using dimeticone.
ZA966452B (en) Process for the preparation of substituted aminocarbonyltriazolinones.
ZA966321B (en) Process for the hydrogenation of imines
EP0604092A3 (en) Improved process for the production of alkyl halosilanes.
SG38905A1 (en) Process for the manufacture of hydroxyalkoxybenzophenones
IL118731A0 (en) Process for the preparation of 2,2-dialkyl-arylidene-cycloalkanones
IL122463A0 (en) Process for the hydrogenation of imines
IL120556A0 (en) Process for the preparation of 3,3,5-trichloroglutarimide