GB9420262D0 - Tryptophan esters as tachykinin receptor antagonists - Google Patents

Tryptophan esters as tachykinin receptor antagonists

Info

Publication number
GB9420262D0
GB9420262D0 GB9420262A GB9420262A GB9420262D0 GB 9420262 D0 GB9420262 D0 GB 9420262D0 GB 9420262 A GB9420262 A GB 9420262A GB 9420262 A GB9420262 A GB 9420262A GB 9420262 D0 GB9420262 D0 GB 9420262D0
Authority
GB
United Kingdom
Prior art keywords
receptor antagonists
tachykinin receptor
tryptophan esters
tryptophan
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9420262A
Other versions
GB2282807A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB9420262D0 publication Critical patent/GB9420262D0/en
Publication of GB2282807A publication Critical patent/GB2282807A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9420262A 1993-10-15 1994-10-07 Tryptophan esters and amides as tachykinin receptor antagonists Withdrawn GB2282807A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13851593A 1993-10-15 1993-10-15

Publications (2)

Publication Number Publication Date
GB9420262D0 true GB9420262D0 (en) 1994-11-23
GB2282807A GB2282807A (en) 1995-04-19

Family

ID=22482366

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9420262A Withdrawn GB2282807A (en) 1993-10-15 1994-10-07 Tryptophan esters and amides as tachykinin receptor antagonists

Country Status (1)

Country Link
GB (1) GB2282807A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO274596A0 (en) * 1996-10-04 1996-10-31 Armstrong, Stuart Maxwell Method for the treatment of neurological or neuropsychiatric disorders
CN1328241C (en) * 2004-09-06 2007-07-25 大连绿源药业有限责任公司 Preparation of N-methy-3,5-ditrifluo-aniline
ITMI20060488A1 (en) * 2006-03-17 2007-09-18 Miteni Spa PROCEDURE FOR THE PREPARATION OF 3,4-BIS TRIFLUORONETIL-N-METHYLBENZYLAMINE
HUP0700782A3 (en) * 2007-12-05 2009-11-30 Biostatin Gyogyszerkutato Fejl Novel peptides and amino acid derivatives, pharmaceutical compositions containing the same and use of the compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1055518B (en) * 1971-05-18 1982-01-11 Rotta Research Lab TRIPTOFANO DERIVATIVES
IE902238A1 (en) * 1989-06-30 1991-01-16 Abbott Lab Tetrapeptide type-b cck receptor ligands

Also Published As

Publication number Publication date
GB2282807A (en) 1995-04-19

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)