GB9213835D0 - Compounds - Google Patents

Compounds

Info

Publication number
GB9213835D0
GB9213835D0 GB929213835A GB9213835A GB9213835D0 GB 9213835 D0 GB9213835 D0 GB 9213835D0 GB 929213835 A GB929213835 A GB 929213835A GB 9213835 A GB9213835 A GB 9213835A GB 9213835 D0 GB9213835 D0 GB 9213835D0
Authority
GB
United Kingdom
Prior art keywords
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB929213835A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Priority to GB929213835A priority Critical patent/GB9213835D0/en
Publication of GB9213835D0 publication Critical patent/GB9213835D0/en
Priority to ZA934645A priority patent/ZA934645B/en
Priority to MA23217A priority patent/MA22927A1/en
Priority to IL106158A priority patent/IL106158A0/en
Priority to CN93109540A priority patent/CN1095382A/en
Priority to APAP/P/1993/000542A priority patent/AP412A/en
Priority to JP6502660A priority patent/JPH08500821A/en
Priority to EP93915499A priority patent/EP0651643A4/en
Priority to CZ943346A priority patent/CZ334694A3/en
Priority to SK1599-94A priority patent/SK159994A3/en
Priority to AU45459/93A priority patent/AU4545993A/en
Priority to PCT/US1993/006238 priority patent/WO1994000125A1/en
Priority to BR9306748A priority patent/BR9306748A/en
Priority to CA002138956A priority patent/CA2138956A1/en
Priority to MX9303970A priority patent/MX9303970A/en
Priority to HU9403833A priority patent/HUT69409A/en
Priority to SI9300350A priority patent/SI9300350A/en
Priority to RU94046378/04A priority patent/RU94046378A/en
Priority to BG99313A priority patent/BG99313A/en
Priority to OA60599A priority patent/OA10122A/en
Priority to KR1019940704802A priority patent/KR950702118A/en
Priority to NO945074A priority patent/NO945074L/en
Priority to FI946189A priority patent/FI946189A0/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB929213835A 1992-06-30 1992-06-30 Compounds Pending GB9213835D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GB929213835A GB9213835D0 (en) 1992-06-30 1992-06-30 Compounds
ZA934645A ZA934645B (en) 1992-06-30 1993-06-26 17-Alkylketone steroids useful as 5-alpha-reductase inhibitors
MA23217A MA22927A1 (en) 1992-06-30 1993-06-28 PROCESS FOR THE PREPARATION OF NEW COMPOUNDS.
IL106158A IL106158A0 (en) 1992-06-30 1993-06-28 Polycyclic compounds
RU94046378/04A RU94046378A (en) 1992-06-30 1993-06-30 17-ALKYLKETONESTEROIDS USEFUL AS INHIBITORS OF 5-α-REDUCTASE, INTERMEDIATE COMPOUNDS, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF PREPARING PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF STEROID-5-a-REDUCTASE IN MAMMALIAN
AU45459/93A AU4545993A (en) 1992-06-30 1993-06-30 17-alkylketone steroids useful as 5-alpha-reductase inhibitors
CA002138956A CA2138956A1 (en) 1992-06-30 1993-06-30 17-alkylketone steroids useful as 5-.alpha.-reductase inhibitors
JP6502660A JPH08500821A (en) 1992-06-30 1993-06-30 17-Alkyl ketone steroids useful as 5-α-reductase inhibitors
EP93915499A EP0651643A4 (en) 1992-06-30 1993-06-30 17-ALKYLKETONE STEROIDS USEFUL AS 5--g(a)-REDUCTASE INHIBITORS.
CZ943346A CZ334694A3 (en) 1992-06-30 1993-06-30 17-alkyl ketone steroids usable as inhibitors of 5-alpha-reductase
SK1599-94A SK159994A3 (en) 1992-06-30 1993-06-30 17-alkylketone steroids useful as 5-alpha-reductase inhibitors
CN93109540A CN1095382A (en) 1992-06-30 1993-06-30 The new A of cyanines family ring steroide
PCT/US1993/006238 WO1994000125A1 (en) 1992-06-30 1993-06-30 17-ALKYLKETONE STEROIDS USEFUL AS 5-α-REDUCTASE INHIBITORS
BR9306748A BR9306748A (en) 1992-06-30 1993-06-30 17-alkylacetone steroids useful as 5-reductase inhibitors
APAP/P/1993/000542A AP412A (en) 1992-06-30 1993-06-30 17a and 17B-Alkylketone-3-carboxyaromatic a ring steroidal compounds and pharmaceutical compositions containing these compounds.
MX9303970A MX9303970A (en) 1992-06-30 1993-06-30 STEROID COMPOUNDS OF RING A OF 17 AND 17ß-ALKYL KETONE-3-CARBOXIAROMATIC.
HU9403833A HUT69409A (en) 1992-06-30 1993-06-30 17-alkylketone-steroids useful as 5-alpha-reductase inhibitors, pharmaceutical compositions containing the same and process for their production and intermediates
SI9300350A SI9300350A (en) 1992-06-30 1993-06-30 17(alpha) and 17(beta)alkylketon-3-carboxyaromatic a cyclic analogs of steroidal synthetic compounds
NO945074A NO945074L (en) 1992-06-30 1994-12-29 17-Alkylethone steroids useful as 5-itators
BG99313A BG99313A (en) 1992-06-30 1994-12-29 117-alkylketonesteroids as 5- -reductase inhibitors
OA60599A OA10122A (en) 1992-06-30 1994-12-29 17-Alkylketone steroids useful as 5-alpha reductase inhibitors
KR1019940704802A KR950702118A (en) 1992-06-30 1994-12-29 17-Alkylketone steroids useful as 5-α-reductase inhibitors
FI946189A FI946189A0 (en) 1992-06-30 1994-12-30 17-alkyl ketone steroids useful as 5-alpha-reductase inhibitors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929213835A GB9213835D0 (en) 1992-06-30 1992-06-30 Compounds

Publications (1)

Publication Number Publication Date
GB9213835D0 true GB9213835D0 (en) 1992-08-12

Family

ID=10717920

Family Applications (1)

Application Number Title Priority Date Filing Date
GB929213835A Pending GB9213835D0 (en) 1992-06-30 1992-06-30 Compounds

Country Status (23)

Country Link
EP (1) EP0651643A4 (en)
JP (1) JPH08500821A (en)
KR (1) KR950702118A (en)
CN (1) CN1095382A (en)
AP (1) AP412A (en)
AU (1) AU4545993A (en)
BG (1) BG99313A (en)
BR (1) BR9306748A (en)
CA (1) CA2138956A1 (en)
CZ (1) CZ334694A3 (en)
FI (1) FI946189A0 (en)
GB (1) GB9213835D0 (en)
HU (1) HUT69409A (en)
IL (1) IL106158A0 (en)
MA (1) MA22927A1 (en)
MX (1) MX9303970A (en)
NO (1) NO945074L (en)
OA (1) OA10122A (en)
RU (1) RU94046378A (en)
SI (1) SI9300350A (en)
SK (1) SK159994A3 (en)
WO (1) WO1994000125A1 (en)
ZA (1) ZA934645B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925774A (en) 1991-01-07 1999-07-20 Pherin Corporation Estrenes for inducing hypothalamic effects
ATE156839T1 (en) * 1992-05-20 1997-08-15 Merck & Co Inc NEW DELTA-17 AND DELTA-20 UNSATURATED AND SATURATED 17--G(B)-SUBSTITUTED-4-AZA-5-G(A)- ANDROSTAN-3-ONE COMPOUNDS AS INHIBITORS OF 5-ALPHA-REDUCTASE
US5543417A (en) * 1994-10-21 1996-08-06 Merck & Co., Inc. Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents
GB201102913D0 (en) 2011-02-18 2011-04-06 Univ Birmingham Novel therapeutic
JP2015129095A (en) 2013-12-19 2015-07-16 ロレアル composition
MX2020008422A (en) * 2018-02-11 2020-09-21 Jiangsu Hansoh Pharmaceutical Group Co Ltd Steroid derivative regulators, method for preparing the same, and uses thereof.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954446A (en) * 1988-05-25 1990-09-04 Smithkline Beecham Corporation Aromatic steroid 5-α-reductase inhibitors

Also Published As

Publication number Publication date
CN1095382A (en) 1994-11-23
SK159994A3 (en) 1996-01-10
IL106158A0 (en) 1993-10-20
BR9306748A (en) 1998-12-08
AP9300542A0 (en) 1993-07-31
BG99313A (en) 1995-09-29
CA2138956A1 (en) 1994-01-06
WO1994000125A1 (en) 1994-01-06
AU4545993A (en) 1994-01-24
CZ334694A3 (en) 1995-10-18
EP0651643A1 (en) 1995-05-10
MX9303970A (en) 1994-04-29
OA10122A (en) 1996-12-18
FI946189A (en) 1994-12-30
AP412A (en) 1995-09-29
KR950702118A (en) 1995-06-19
JPH08500821A (en) 1996-01-30
ZA934645B (en) 1994-01-25
RU94046378A (en) 1996-10-10
FI946189A0 (en) 1994-12-30
MA22927A1 (en) 1994-04-01
SI9300350A (en) 1993-12-31
HUT69409A (en) 1995-09-28
EP0651643A4 (en) 1995-10-04
NO945074L (en) 1995-02-16
NO945074D0 (en) 1994-12-29

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