GB912496A - Amides and process for their preparation - Google Patents
Amides and process for their preparationInfo
- Publication number
- GB912496A GB912496A GB7702/61A GB770261A GB912496A GB 912496 A GB912496 A GB 912496A GB 7702/61 A GB7702/61 A GB 7702/61A GB 770261 A GB770261 A GB 770261A GB 912496 A GB912496 A GB 912496A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- methyl
- aminomethyl
- acid
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title abstract 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- -1 azido, phenylthio, p-nitrophenylthio Chemical group 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- TYLNHTDUMUASSM-UHFFFAOYSA-N (2-methylpyridin-4-yl)methanamine;dihydrochloride Chemical compound Cl.Cl.CC1=CC(CN)=CC=N1 TYLNHTDUMUASSM-UHFFFAOYSA-N 0.000 abstract 1
- BGPRENMUEYJKJN-UHFFFAOYSA-N 2-(butylamino)-6-methylpyridine-3-carbonitrile Chemical compound CCCCNC1=NC(C)=CC=C1C#N BGPRENMUEYJKJN-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical class CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- ABIRGXQDAZTINS-UHFFFAOYSA-N 2-amino-6-methylpyridine-3-carbonitrile Chemical compound CC1=CC=C(C#N)C(N)=N1 ABIRGXQDAZTINS-UHFFFAOYSA-N 0.000 abstract 1
- JVWPZCCMTFKYHN-UHFFFAOYSA-N 2-chloro-4,6-dimethyl-5-nitropyridine-3-carbonitrile Chemical compound CC1=NC(Cl)=C(C#N)C(C)=C1[N+]([O-])=O JVWPZCCMTFKYHN-UHFFFAOYSA-N 0.000 abstract 1
- YSBNBAYNISAUIT-UHFFFAOYSA-N 2-chloro-6-methylpyridine-3-carbonitrile Chemical compound CC1=CC=C(C#N)C(Cl)=N1 YSBNBAYNISAUIT-UHFFFAOYSA-N 0.000 abstract 1
- LLJWMOIQRXDJLC-UHFFFAOYSA-N 3-(aminomethyl)-6-methylpyridin-2-amine hydrochloride Chemical compound Cl.NC1=NC(=CC=C1CN)C LLJWMOIQRXDJLC-UHFFFAOYSA-N 0.000 abstract 1
- ZPKOFJCBVANNIO-UHFFFAOYSA-N 3-(aminomethyl)-N,6-dimethylpyridin-2-amine dihydrochloride Chemical compound Cl.Cl.NCC=1C(=NC(=CC1)C)NC ZPKOFJCBVANNIO-UHFFFAOYSA-N 0.000 abstract 1
- FIZXMXCIWQOOLG-UHFFFAOYSA-N 3-(aminomethyl)-N-butyl-6-methylpyridin-2-amine hydrochloride Chemical compound Cl.NCC=1C(=NC(=CC1)C)NCCCC FIZXMXCIWQOOLG-UHFFFAOYSA-N 0.000 abstract 1
- BNRLYIXANMDGGL-UHFFFAOYSA-N 3-(aminomethyl)pyridin-2-amine dihydrochloride Chemical compound Cl.Cl.NC1=NC=CC=C1CN BNRLYIXANMDGGL-UHFFFAOYSA-N 0.000 abstract 1
- BHOOPQZQRVONAL-UHFFFAOYSA-N 4-methyl-n-(pyridin-3-ylmethyl)benzenesulfonamide Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NCC1=CC=CN=C1 BHOOPQZQRVONAL-UHFFFAOYSA-N 0.000 abstract 1
- ZQQYYFBTCSNSCW-UHFFFAOYSA-N 5-(aminomethyl)-2,4-dimethylpyridin-3-amine hydrate dihydrochloride Chemical compound O.Cl.Cl.NC=1C(=C(C=NC1C)CN)C ZQQYYFBTCSNSCW-UHFFFAOYSA-N 0.000 abstract 1
- RENMDAKOXSCIGH-UHFFFAOYSA-N Chloroacetonitrile Chemical compound ClCC#N RENMDAKOXSCIGH-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical class CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 1
- GRHZLQBPAJAHDM-SPRQWYLLSA-N [(3as,4r,6ar)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] n-[(2s,4s,5s)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate Chemical group CC1=CC=CC(C)=C1OCC(=O)N[C@H]([C@@H](O)C[C@H](CC=1C=CC=CC=1)NC(=O)O[C@@H]1[C@@H]2CCO[C@@H]2OC1)CC1=CC=CC=C1 GRHZLQBPAJAHDM-SPRQWYLLSA-N 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical class [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- GRSTVVGJSKHCCS-UHFFFAOYSA-N bis(1h-imidazol-2-yl)methanone Chemical compound N=1C=CNC=1C(=O)C1=NC=CN1 GRSTVVGJSKHCCS-UHFFFAOYSA-N 0.000 abstract 1
- HQABUPZFAYXKJW-UHFFFAOYSA-N butan-1-amine Chemical compound CCCCN HQABUPZFAYXKJW-UHFFFAOYSA-N 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001916 cyano esters Chemical class 0.000 abstract 1
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- FNRBNCKQGYSTKZ-UHFFFAOYSA-N n,4-dimethyl-n-(pyridin-3-ylmethyl)benzenesulfonamide Chemical compound C=1C=C(C)C=CC=1S(=O)(=O)N(C)CC1=CC=CN=C1 FNRBNCKQGYSTKZ-UHFFFAOYSA-N 0.000 abstract 1
- GFYIOWAZURZNJP-UHFFFAOYSA-N n-methyl-1-pyridin-3-ylmethanamine;dihydrochloride Chemical compound Cl.Cl.CNCC1=CC=CN=C1 GFYIOWAZURZNJP-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- FAIAAWCVCHQXDN-UHFFFAOYSA-N phosphorus trichloride Chemical compound ClP(Cl)Cl FAIAAWCVCHQXDN-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- HDOUGSFASVGDCS-UHFFFAOYSA-N pyridin-3-ylmethanamine Chemical compound NCC1=CC=CN=C1 HDOUGSFASVGDCS-UHFFFAOYSA-N 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE601787A BE601787A (fr) | 1960-04-14 | 1961-03-24 | Nouveaux dérivés de N-pyridylméthyl-benzamides et leur préparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2209060A | 1960-04-14 | 1960-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB912496A true GB912496A (en) | 1962-12-12 |
Family
ID=21807762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7702/61A Expired GB912496A (en) | 1960-04-14 | 1961-03-02 | Amides and process for their preparation |
Country Status (5)
| Country | Link |
|---|---|
| ES (1) | ES265741A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR1027M (cg-RX-API-DMAC10.html) |
| GB (1) | GB912496A (cg-RX-API-DMAC10.html) |
| LU (1) | LU39929A1 (cg-RX-API-DMAC10.html) |
| MC (1) | MC302A1 (cg-RX-API-DMAC10.html) |
-
1961
- 1961-03-02 GB GB7702/61A patent/GB912496A/en not_active Expired
- 1961-03-14 ES ES0265741A patent/ES265741A1/es not_active Expired
- 1961-03-17 MC MC308A patent/MC302A1/fr unknown
- 1961-03-20 FR FR856095A patent/FR1027M/fr active Active
- 1961-03-24 LU LU39929D patent/LU39929A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU39929A1 (cg-RX-API-DMAC10.html) | 1961-05-24 |
| ES265741A1 (es) | 1961-10-16 |
| MC302A1 (fr) | 1962-01-29 |
| FR1027M (fr) | 1962-01-02 |
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