GB874520A - Amphetamine barbiturates and compositions thereof - Google Patents

Amphetamine barbiturates and compositions thereof

Info

Publication number
GB874520A
GB874520A GB28075/59A GB2807559A GB874520A GB 874520 A GB874520 A GB 874520A GB 28075/59 A GB28075/59 A GB 28075/59A GB 2807559 A GB2807559 A GB 2807559A GB 874520 A GB874520 A GB 874520A
Authority
GB
United Kingdom
Prior art keywords
ethyl
amphetamine
phenyl
barbituric
barbituric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28075/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of GB874520A publication Critical patent/GB874520A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids
    • C07D239/64Salts of organic bases; Organic double compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention comprises amphetamine salts of barbituric acids, for example the 5-ethyl-5-a -methylbutyl-and 5-ethyl-5-phenyl-barbituric acids prepared by reacting equimolecular quantities of the amine and the substituted barbituric acid. The products are used pharmaceutically as anorexic agents (see Group VI).ALSO:Anorexic preparations comprise an amphetamine salt of a barbituric acid, e.g. 5-ethyl-5-a -methylbutyl- and 5-ethyl-5-phenyl-barbituric acid, in a dosage unit form, e.g. a tablet or capsule, which may also contain an inert pharmaceutical excipient. Preferably the preparations contain 10 to 15 mg. of the salt per dosage unit. Examples describe capsules comprising amphetamine 5 - ethyl - 5 - phenyl - barbiturate.
GB28075/59A 1958-09-04 1959-08-17 Amphetamine barbiturates and compositions thereof Expired GB874520A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US874520XA 1958-09-04 1958-09-04

Publications (1)

Publication Number Publication Date
GB874520A true GB874520A (en) 1961-08-10

Family

ID=22205268

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28075/59A Expired GB874520A (en) 1958-09-04 1959-08-17 Amphetamine barbiturates and compositions thereof

Country Status (1)

Country Link
GB (1) GB874520A (en)

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