GB856493A - Therapeutic compositions comprising tetracycline antibiotics - Google Patents

Therapeutic compositions comprising tetracycline antibiotics

Info

Publication number
GB856493A
GB856493A GB30645/58A GB3064558A GB856493A GB 856493 A GB856493 A GB 856493A GB 30645/58 A GB30645/58 A GB 30645/58A GB 3064558 A GB3064558 A GB 3064558A GB 856493 A GB856493 A GB 856493A
Authority
GB
United Kingdom
Prior art keywords
glucosamine
salts
acyl
tetracycline
demethyltetracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30645/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB856493A publication Critical patent/GB856493A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Veterinary and pharmaceutical compositions for oral use comprise at least one tetracycline type antibiotic and at least one of the compounds; glucosamine, glucosamine salts, N-acyl glucosamines. Specified antibiotics are tetracycline, oxytetracycline; chlortetracycline, bromtetracycline, 6 - demethyl-chlortetracycline, 6 - demethyltetracycline, 6-deoxy-6-demethyltetracycline in their amphoteric forms and as salts with acids and bases, as complexes with polyvalent metal compounds and as derivatives such as esters which have similar biological activity as the parent antibiotics. Specified glucosamine salts are those non-toxic salts formed from the base and organic or inorganic acids e.g. the phosphate, sulphate, hydrochloride, hydrobromide, citrate, tartrate, succinate and ralicylate. The N-acyl glucosamines may be those in which the acyl group is a lower (C1 to 6) aliphatic acyl group e.g. acetyl, propionyl, butyryl. The ratio by weight of antibiotic to glucosamine compound may be from about 3:1 to 1:3 and is preferably about 1:1.
GB30645/58A 1957-10-04 1958-09-25 Therapeutic compositions comprising tetracycline antibiotics Expired GB856493A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US856493XA 1957-10-04 1957-10-04

Publications (1)

Publication Number Publication Date
GB856493A true GB856493A (en) 1960-12-21

Family

ID=22193041

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30645/58A Expired GB856493A (en) 1957-10-04 1958-09-25 Therapeutic compositions comprising tetracycline antibiotics

Country Status (1)

Country Link
GB (1) GB856493A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328258A (en) * 1962-09-10 1967-06-27 Lipha Anti-microbial therapeutics consisting of nitrofurantoin, tetracycline, and d-glucosamine
EP1053000A1 (en) * 1998-02-13 2000-11-22 Nutramax Laboratories, Inc. Agents and methods for protection, treatment and repair of connective tissue
EP1083929A2 (en) * 1998-06-05 2001-03-21 Nutramax Laboratories, Inc. The use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
EP1461045A2 (en) * 2001-12-07 2004-09-29 Cargill, Incorporated Glucosamine organic acid adducts

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328258A (en) * 1962-09-10 1967-06-27 Lipha Anti-microbial therapeutics consisting of nitrofurantoin, tetracycline, and d-glucosamine
EP1053000A1 (en) * 1998-02-13 2000-11-22 Nutramax Laboratories, Inc. Agents and methods for protection, treatment and repair of connective tissue
EP1053000A4 (en) * 1998-02-13 2003-01-29 Nutramax Lab Inc Agents and methods for protection, treatment and repair of connective tissue
EP1917966A1 (en) * 1998-02-13 2008-05-07 Nutramax Laboratories, Inc. Agents and methods for protection treatment and repair of connective tissue
EP1083929A2 (en) * 1998-06-05 2001-03-21 Nutramax Laboratories, Inc. The use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
EP1083929A4 (en) * 1998-06-05 2002-11-27 Nutramax Lab Inc The use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
AU770010B2 (en) * 1998-06-05 2004-02-12 Nutramax Laboratories, Inc. Agents and methods for protection, treatment and repair of connective tissue
EP1461045A2 (en) * 2001-12-07 2004-09-29 Cargill, Incorporated Glucosamine organic acid adducts
EP1461045A4 (en) * 2001-12-07 2005-10-19 Cargill Inc Glucosamine organic acid adducts

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