GB855486A - Novel heterocyclic hydrazine derivatives and a process for the manufacture thereof - Google Patents

Novel heterocyclic hydrazine derivatives and a process for the manufacture thereof

Info

Publication number
GB855486A
GB855486A GB10088/59A GB1008859A GB855486A GB 855486 A GB855486 A GB 855486A GB 10088/59 A GB10088/59 A GB 10088/59A GB 1008859 A GB1008859 A GB 1008859A GB 855486 A GB855486 A GB 855486A
Authority
GB
United Kingdom
Prior art keywords
general formula
carbon atoms
acid addition
acid
carbonyl compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10088/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB855486A publication Critical patent/GB855486A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

The invention comprises compounds of the general formula: <FORM:0855486/IV(b)/1> and their acid addition salts, wherein R1 represents a thiophene, pyrrole a N-alkyl pyrrole radical (which may contain one or more halogen, alkyl or alkoxy substituents attached respectively to a carbon atom or carbon atoms thereof and R2 represents an aralkyl radical, a saturated dicyclic hydrocarbon radical containing not more than seven carbon atoms or a saturated branched-or straight-chain aliphatic hydrocarbon radical containing not more than seven carbon atoms and the preparation thereof by (a) condensing an acid of the general formula: <FORM:0855486/IV(b)/2> or a salt thereof, with a substituted hydrazine of the general formula: H2N-NH-R2 in the presence of an N,N1-disubstituted-carbodiimide, and if desired, converting the condensation product into an acid addition salt or, if an acid addition salt, into the base or (b) reacting a hydrozide of the above acid with an appropriate carbonyl compound and simultaneously or consecutively reducing the resulting hydrazone of the carbonyl compound.
GB10088/59A 1958-03-28 1959-03-24 Novel heterocyclic hydrazine derivatives and a process for the manufacture thereof Expired GB855486A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH855486X 1958-03-28

Publications (1)

Publication Number Publication Date
GB855486A true GB855486A (en) 1960-11-30

Family

ID=4542654

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10088/59A Expired GB855486A (en) 1958-03-28 1959-03-24 Novel heterocyclic hydrazine derivatives and a process for the manufacture thereof

Country Status (1)

Country Link
GB (1) GB855486A (en)

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