GB8510222D0 - Anthracycline-anionic polymer conjugates - Google Patents

Anthracycline-anionic polymer conjugates

Info

Publication number
GB8510222D0
GB8510222D0 GB858510222A GB8510222A GB8510222D0 GB 8510222 D0 GB8510222 D0 GB 8510222D0 GB 858510222 A GB858510222 A GB 858510222A GB 8510222 A GB8510222 A GB 8510222A GB 8510222 D0 GB8510222 D0 GB 8510222D0
Authority
GB
United Kingdom
Prior art keywords
anthracycline
anionic polymer
polymer conjugates
conjugates
anionic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB858510222A
Other versions
GB2158078B (en
GB2158078A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of GB8510222D0 publication Critical patent/GB8510222D0/en
Publication of GB2158078A publication Critical patent/GB2158078A/en
Application granted granted Critical
Publication of GB2158078B publication Critical patent/GB2158078B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB08510222A 1984-05-25 1985-04-22 Anthracycline-anionic polymer conjugates Expired GB2158078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848413464A GB8413464D0 (en) 1984-05-25 1984-05-25 Anthracycline-anionic polymer conjugates

Publications (3)

Publication Number Publication Date
GB8510222D0 true GB8510222D0 (en) 1985-05-30
GB2158078A GB2158078A (en) 1985-11-06
GB2158078B GB2158078B (en) 1987-09-16

Family

ID=10561522

Family Applications (2)

Application Number Title Priority Date Filing Date
GB848413464A Pending GB8413464D0 (en) 1984-05-25 1984-05-25 Anthracycline-anionic polymer conjugates
GB08510222A Expired GB2158078B (en) 1984-05-25 1985-04-22 Anthracycline-anionic polymer conjugates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB848413464A Pending GB8413464D0 (en) 1984-05-25 1984-05-25 Anthracycline-anionic polymer conjugates

Country Status (4)

Country Link
JP (1) JPS6156128A (en)
BE (1) BE902344A (en)
DE (1) DE3515178A1 (en)
GB (2) GB8413464D0 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU46858B (en) * 1987-03-11 1994-06-24 Farmitalia Carlo Erba S.R.L. PROCEDURE FOR OBTAINING IMMUNOGLOBULIN CONJUGATES
DE3853493T2 (en) * 1987-05-28 1995-07-27 Hiroshi Maeda Superoxide dismutase derivatives, process for their preparation and their use as medicines.
IT1230505B (en) * 1988-10-11 1991-10-25 Sicor Spa PROCEDURE FOR THE CONVERSION OF DAUNORUBICINA IN DOXORUBICINA.
EP0408019A3 (en) * 1989-07-12 1992-10-14 Union Carbide Chemicals And Plastics Company, Inc. Pharmaceutical active derivative delivery systems
US5378456A (en) * 1993-03-25 1995-01-03 American Cyanamid Company Antitumor mitoxantrone polymeric compositions
US5609867A (en) 1994-11-01 1997-03-11 American Cyanamid Company Polymeric antitumor agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602967A (en) * 1977-07-16 1981-11-18 Hercules Inc Reaction prodcut of methotrexate with divinyl ether and maleic anhydride copolymer

Also Published As

Publication number Publication date
BE902344A (en) 1985-09-02
DE3515178A1 (en) 1985-11-28
GB2158078B (en) 1987-09-16
JPS6156128A (en) 1986-03-20
GB8413464D0 (en) 1984-07-04
GB2158078A (en) 1985-11-06

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee