GB787912A - Stable steroid compositions - Google Patents
Stable steroid compositionsInfo
- Publication number
- GB787912A GB787912A GB10686/55A GB1068655A GB787912A GB 787912 A GB787912 A GB 787912A GB 10686/55 A GB10686/55 A GB 10686/55A GB 1068655 A GB1068655 A GB 1068655A GB 787912 A GB787912 A GB 787912A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sodium
- vitamins
- citrate
- mixture
- aqueous suspension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
An aqueous therapeutic composition comprises a water-insoluble steroid subject to crystal growth in aqueous suspension, e.g. cortisone acetate, cortisone acetate hydrate, estradiol monobenzoate, testosterone propionate, progesterone or their 9 a -halo compounds, and from 0.01 to 10 per cent weight (gm.) to volume (c.c.) of polyvinyl pyrrolidone, polyvinyl alcohol or a mixture thereof. The composition may also take the form of a dry composition suitable for the extemporaneous preparation of an aqueous suspension suitable for oral, topical, or parenteral administration, and may also contain antibiotics and vitamins, e.g. penicillin O and G, procaine penicillin, bacitracin, chloramphenical, streptomycin, dihydrostreptomycin, erythromycin, oxytetracycline, chlortetracycline, tetracycline, polymyxin, circulin, endomycin, neomycin base, neomycin sulphate, hydrochloride or citrate, Vitamins A, B, B12, C, riboflavin, pyridoxine and mixture thereof. Other substances which may be present are buffers, e.g. sodium citrate, to maintain a pH of between 6.5 and 8.0, preservatives, e.g. myristyl gamma picolinium chloride, sodium ethyl mercurithiosalicylate, chlorobutanol, methylparaben, benzyl alcohol or phenol, isotonic agents, e.g. sodium chloride, lubricants, e.g. glycerol, sorbitol, wetting agents, e.g. polyoxyethylene sorbitan mono-oleate, and dextrose, sucrose, saccharin, pectin, acacia, dextran, sodium alginate, sodium citrate and benzoic acid.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US787912XA | 1954-05-04 | 1954-05-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB787912A true GB787912A (en) | 1957-12-18 |
Family
ID=22146248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB10686/55A Expired GB787912A (en) | 1954-05-04 | 1955-04-13 | Stable steroid compositions |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB787912A (en) |
-
1955
- 1955-04-13 GB GB10686/55A patent/GB787912A/en not_active Expired
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