GB786753A - Improvements in or relating to pyrazole compounds and compositions containing them - Google Patents

Improvements in or relating to pyrazole compounds and compositions containing them

Info

Publication number
GB786753A
GB786753A GB424955A GB424955A GB786753A GB 786753 A GB786753 A GB 786753A GB 424955 A GB424955 A GB 424955A GB 424955 A GB424955 A GB 424955A GB 786753 A GB786753 A GB 786753A
Authority
GB
United Kingdom
Prior art keywords
isopropylpyrazole
nitroso
dimethyl
compositions containing
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB424955A
Inventor
Wilfred Arthur Freeman
Ronald Slack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Priority to GB424955A priority Critical patent/GB786753A/en
Publication of GB786753A publication Critical patent/GB786753A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises 3:5-dimethyl-4-nitroso-1-isopropylpyrazole and its preparation by nitrosating acetylacetone and condensing the resulting nitrosoketone with isopropylhydrazine.ALSO:Fungicidal compositions comprise as the active ingredient 3 : 5-dimethyl-4-nitroso-1-isopropylpyrazole admixed with a diluent. Preferably the compositions contain at least 0.05 per cent by weight of the active compound. Examples describe compositions containing 3 : 5 - dimethyl - 4 - nitroso - 1 - isopropylpyrazole comprising (1) a wettable powder containing silicaceous earth and a wetting agent for the formulation of aqueous dispersions used to spray plants; (2) a solution in industrial methylated spirit for the treatment of ringworm in cattle; and (3) a cream containing castor oil, stearyl alcohol and polyethylene glycol monostearate for topical use on the human body. The Provisional Specification also describes the use of the compound as a therapeutic agent against Mycobacterium tuberculosis, for which purpose it is made up in pharmaceutical diluents, for example in tablets, powders or capsules, or in sterile solutions for injection.
GB424955A 1955-02-12 1955-02-12 Improvements in or relating to pyrazole compounds and compositions containing them Expired GB786753A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB424955A GB786753A (en) 1955-02-12 1955-02-12 Improvements in or relating to pyrazole compounds and compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB424955A GB786753A (en) 1955-02-12 1955-02-12 Improvements in or relating to pyrazole compounds and compositions containing them

Publications (1)

Publication Number Publication Date
GB786753A true GB786753A (en) 1957-11-27

Family

ID=9773547

Family Applications (1)

Application Number Title Priority Date Filing Date
GB424955A Expired GB786753A (en) 1955-02-12 1955-02-12 Improvements in or relating to pyrazole compounds and compositions containing them

Country Status (1)

Country Link
GB (1) GB786753A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1151804B (en) * 1958-12-03 1963-07-25 May & Baker Ltd Process for the preparation of pyrazole derivatives
DE1162376B (en) * 1959-10-26 1964-02-06 May &. Baker Limited, Dagenham, Essex (Großbritannien) Process for the preparation of 4-nitro-pyrazole derivatives.
EP0047850A2 (en) * 1980-08-09 1982-03-24 Bayer Ag Use of 4-nitroso-pyrazoles in microbiocidal compositions
EP1406712A2 (en) * 2001-07-13 2004-04-14 Benchmark Research & Technology, Inc. Suspensions of particles in non-aqueous solvents
WO2007020426A1 (en) * 2005-08-19 2007-02-22 Astrazeneca Ab Pyrazolone derivatives for the treatment of tuberculosis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1151804B (en) * 1958-12-03 1963-07-25 May & Baker Ltd Process for the preparation of pyrazole derivatives
DE1162376B (en) * 1959-10-26 1964-02-06 May &. Baker Limited, Dagenham, Essex (Großbritannien) Process for the preparation of 4-nitro-pyrazole derivatives.
EP0047850A2 (en) * 1980-08-09 1982-03-24 Bayer Ag Use of 4-nitroso-pyrazoles in microbiocidal compositions
EP0047850A3 (en) * 1980-08-09 1982-04-21 Bayer Ag 4-nitroso-pyrazoles as microbicides
EP1406712A2 (en) * 2001-07-13 2004-04-14 Benchmark Research & Technology, Inc. Suspensions of particles in non-aqueous solvents
EP1406712A4 (en) * 2001-07-13 2006-10-25 Benchmark Res & Technology Inc Suspensions of particles in non-aqueous solvents
WO2007020426A1 (en) * 2005-08-19 2007-02-22 Astrazeneca Ab Pyrazolone derivatives for the treatment of tuberculosis

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