GB786065A - Chromonyl-3-(4-hydroxycoumarinyl-3)-acetic acid derivatives and compositions containing them - Google Patents

Chromonyl-3-(4-hydroxycoumarinyl-3)-acetic acid derivatives and compositions containing them

Info

Publication number
GB786065A
GB786065A GB21427/54A GB2142754A GB786065A GB 786065 A GB786065 A GB 786065A GB 21427/54 A GB21427/54 A GB 21427/54A GB 2142754 A GB2142754 A GB 2142754A GB 786065 A GB786065 A GB 786065A
Authority
GB
United Kingdom
Prior art keywords
hydroxycoumarinyl
chromonyl
acetic acid
ethyl
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21427/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Spojene Farmaceuticke Zavody
Original Assignee
Spofa Spojene Farmaceuticke Zavody
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Farmaceuticke Zavody filed Critical Spofa Spojene Farmaceuticke Zavody
Publication of GB786065A publication Critical patent/GB786065A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
    • C07D311/48Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring with two such benzopyran radicals linked together by a carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises the ethyl ester of chromonyl - 3 - (41 - hydroxycoumarinyl - 31)-acetic acid, its water-soluble alkali metal and ammonium salts, and a method for the preparation of esters of chromonyl-3-(41-hydroxycoumarinyl-31)-acetic acid (and also the sodium salt thereof) by cyclizing the appropriate ester of a - (4 - hydroxycoumarinyl - 3) - b - salicyloylpropionic acid with an alkyl formate and metallic sodium followed by acidification, if desired, of the sodium salt obtained. In an example: a - (41 - hydroxycoumarinyl - 31) - b - salicyloyl-propionic acid ethyl ester in cooled ethyl formate is treated with powdered sodium and the resulting sodium salt dissolved in water and acidified yielding ethyl chromonyl-3-(41-hydroxycoumarinyl-31)-acetate. Other esters mentioned are methyl, propyl, isopropyl, n-butyl, isobutyl and benzyl.ALSO:Raticidal compositions comprise an ester of chromonyl - 3 - (41 - hydroxycoumarinyl - 31) - acetic acid or a water-soluble alkali metal or ammonium salt thereof together with an edilbe bait. Specified esters are methyl, ethyl, propyl, isopropyl, n-butyl, isobutyl and benzyl.
GB21427/54A 1953-07-23 1954-07-22 Chromonyl-3-(4-hydroxycoumarinyl-3)-acetic acid derivatives and compositions containing them Expired GB786065A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS326368X 1953-07-23

Publications (1)

Publication Number Publication Date
GB786065A true GB786065A (en) 1957-11-13

Family

ID=5452206

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21427/54A Expired GB786065A (en) 1953-07-23 1954-07-22 Chromonyl-3-(4-hydroxycoumarinyl-3)-acetic acid derivatives and compositions containing them

Country Status (6)

Country Link
BE (1) BE530545A (en)
CH (1) CH326368A (en)
DE (1) DE964326C (en)
FR (1) FR1229604A (en)
GB (1) GB786065A (en)
NL (2) NL88453C (en)

Also Published As

Publication number Publication date
NL88453C (en)
DE964326C (en) 1957-05-23
NL189445B (en)
CH326368A (en) 1957-12-15
FR1229604A (en) 1960-09-08
BE530545A (en)

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