GB734117A - Preparation of a substance for the treatment of malignant tumours - Google Patents

Preparation of a substance for the treatment of malignant tumours

Info

Publication number
GB734117A
GB734117A GB1066852A GB1066852A GB734117A GB 734117 A GB734117 A GB 734117A GB 1066852 A GB1066852 A GB 1066852A GB 1066852 A GB1066852 A GB 1066852A GB 734117 A GB734117 A GB 734117A
Authority
GB
United Kingdom
Prior art keywords
precipitate
centrifuged
few days
solvent
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1066852A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB1066852A priority Critical patent/GB734117A/en
Publication of GB734117A publication Critical patent/GB734117A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A substance suitable for the treatment of malignant tumours such as cancer, is prepared by treating (a) female animal blood taken during a period of from a few days before to a few days after delivery or taken during the first few days of menstruation, or (b) colostrum, undiluted with water, with an excess of a substantially non-aqueous water-miscible solvent to precipitate protein bodies containing the active substance, separating the solvent from and drying the precipitate and dispersing the dried precipitate in a neutral to slightly alkaline physiological solution. In the example, human colostrum is centrifuged to remove fat, coated to 0 DEG C. and allowed to stand. Absolute alcohol at 0 DEG C. is added slowly over 10 minutes, the mixture allowed to stand at room temperature for 50 minutes and then cooled to 0 DEG C. The precipitate is centrifuged and alcohol removed in vacuo at 45 DEG C. The precipitate is eluted with physiological saline solution containing disodium phosphate, stirred with bolus alba and centrifuged. The liquid obtained contains the active principle and can be injected, taken orally, or freeze dried to form a powder which is mixed with sterile water as required. Kaolin or fuller's earth may be used in place of bolus alba. The non-aqueous solvent may be absolute ethyl alcohol or acetone. Reference is made to the Cancer Act 1939.
GB1066852A 1952-04-28 1952-04-28 Preparation of a substance for the treatment of malignant tumours Expired GB734117A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1066852A GB734117A (en) 1952-04-28 1952-04-28 Preparation of a substance for the treatment of malignant tumours

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1066852A GB734117A (en) 1952-04-28 1952-04-28 Preparation of a substance for the treatment of malignant tumours

Publications (1)

Publication Number Publication Date
GB734117A true GB734117A (en) 1955-07-27

Family

ID=9972078

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1066852A Expired GB734117A (en) 1952-04-28 1952-04-28 Preparation of a substance for the treatment of malignant tumours

Country Status (1)

Country Link
GB (1) GB734117A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3024623A1 (en) * 1979-07-02 1981-01-22 Assier De Pompignan MEDIUM FOR EXTERNAL APPLICATION BASED ON COLOSTRUM

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3024623A1 (en) * 1979-07-02 1981-01-22 Assier De Pompignan MEDIUM FOR EXTERNAL APPLICATION BASED ON COLOSTRUM

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