GB653341A - An improved alginate medical or surgical preparation - Google Patents

An improved alginate medical or surgical preparation

Info

Publication number
GB653341A
GB653341A GB1153148A GB1153148A GB653341A GB 653341 A GB653341 A GB 653341A GB 1153148 A GB1153148 A GB 1153148A GB 1153148 A GB1153148 A GB 1153148A GB 653341 A GB653341 A GB 653341A
Authority
GB
United Kingdom
Prior art keywords
calcium
alginate
gauze
water
ions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1153148A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB1153148A priority Critical patent/GB653341A/en
Publication of GB653341A publication Critical patent/GB653341A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Fibres or gauze of a double alginate of a water-solubilizing and water-insolubilizing base are prepared by replacing all the H ions of alginic acid by solubilizing and insolubilizing ions in a random manner and in such proportions that the composition so formed can swell to any desired degree in watery fluids but cannot disperse. A water-insoluble alginate such as calcium alginate gauze, may be leached with acid, e.g. hydrochloric or acetic to remove all positive ions, immersed in a water-miscible vehicle such as ethyl alcohol and a known amount of CaCl2 or calcium acetate added. The alcoholized gauze is then neutralized with sodium hydroxide to produce a calcium-sodium alginate of known composition. Alternatively, the calcium alginate gauze may be leached with sufficient acid to leave a predetermined residual calcium content and the gauze so treated then neutralized with sodium hydroxide. Zinc ions may be used instead of calcium, and potassium ammonium or magnesium in place of the sodium ions.ALSO:A double alginate of a water-solubilizing and water-insolubilizing base is prepared by replacing all the hydrogen ions of alginic acid by solubilizing and insolubilizing ions in a random manner and in such proportions that the composition so formed can swell to any desired degree in watery fluids but cannot disperse. A water-insoluble alginate such as calcium alginate gauze, may be leached with acid, e.g. hydrochloric or acetic to remove all positive ions, immersed in a water-miscible vehicle such as ethyl alcohol and a known amount of calcium chlorides or calcium acetate added. The alcoholized gauze is then neutralized with sodium hydroxide to produce a calcium-sodium alginate of known composition. Alternatively, the calcium alginate gauze may be leached with sufficient acid to leave a pre-determined residual calcium content and the gauze so treated then neutralized with sodium hydroxide. Zinc ions may be used instead of calcium, and potassium, ammonium or magnesium in place of sodium ions.ALSO:A coherent medical or surgical preparation consisting of a double alginate of a water-solubilizing and water insolubilizing base is prepared by replacing the H-ions of alginic acid by solubilizing and insolubilizing ions in a random manner and in such proportions that the composition so formed can swell to any desired degree in watery fluids but cannot disperse. A water-insoluble alginate such as calcium alginate gauze, may be backed with acid, e.g. hydrochloric or acetic to remove all positive ions, immersed in a water miscible vehicle such as ethyl alcohol and a known amount of calcium chloride or acetate added. The alcoholized gauze is then neutralized with sodium hydroxide to produce a calcium/sodium alginate of known composition. Alternatively, the calcium alginate gauze may be backed with sufficient acid to leave a predetermined residual calcium percentage and the gauze so treated neutralized as before with sodium hydroxide. Any water-insoluble alginate such as zinc may be used in place of the calcium alginate and potassium ammonium or magnesium, may be used in place of the sodium alginate. As the solubilities of the mixtures vary with the relative proportions of the soluble to insoluble alginates in the mixture, it is possible to prepare a series of products of graded solubilities in the body fluids. Anti-biotics, chemotherapeutics and antiseptic may be incorporated in the preparations.
GB1153148A 1948-04-27 1948-04-27 An improved alginate medical or surgical preparation Expired GB653341A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1153148A GB653341A (en) 1948-04-27 1948-04-27 An improved alginate medical or surgical preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1153148A GB653341A (en) 1948-04-27 1948-04-27 An improved alginate medical or surgical preparation

Publications (1)

Publication Number Publication Date
GB653341A true GB653341A (en) 1951-05-16

Family

ID=9987938

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1153148A Expired GB653341A (en) 1948-04-27 1948-04-27 An improved alginate medical or surgical preparation

Country Status (1)

Country Link
GB (1) GB653341A (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562110A (en) * 1981-08-18 1985-12-31 Tong David Philip Process for the production of alginate fibre material and products made therefrom
EP0227553A2 (en) * 1985-12-26 1987-07-01 Société PRECIS Process for the preparation of a flexible calcium alginate film
US4793337A (en) * 1986-11-17 1988-12-27 E. R. Squibb & Sons, Inc. Adhesive structure and products including same
WO1990001954A1 (en) * 1988-08-31 1990-03-08 Britcair Limited Wound dressing
EP0380253A3 (en) * 1989-01-24 1990-10-10 Minnesota Mining And Manufacturing Company Alginate hydrogel foam wound dressing
EP0476756A1 (en) 1990-09-17 1992-03-25 Cv Laboratories Limited Improved absorbency alginate fabric and a method for its preparation
US5197945A (en) * 1988-05-31 1993-03-30 Minnesota Mining And Manufacturing Company Alginate wound dressing of good integrity
US5230853A (en) * 1990-04-23 1993-07-27 Merck & Co., Inc. Process for making polysaccharide fibers
US5238685A (en) * 1988-08-31 1993-08-24 Britcair Limited Wound dressing
US5292525A (en) * 1992-10-14 1994-03-08 Merck & Co., Inc. Method and composition for removing an alginate from a cutaneous substrate
WO1996014453A1 (en) * 1994-11-02 1996-05-17 E.R. Squibb & Sons Inc. Alginate ropes, method of preparation and use
FR2755613A1 (en) * 1996-11-13 1998-05-15 Precis DRESSING MATERIAL HAVING CALCIUM ALGINATE MATRIX AND PROCESS FOR PRODUCING THE SAME
US5840777A (en) * 1992-06-19 1998-11-24 Albany International Corp. Method of producing polysaccharide foams
CN105755578A (en) * 2015-12-25 2016-07-13 青岛海之林生物科技开发有限公司 Application and preparation method of water-soluble calcium alginate fibers

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562110A (en) * 1981-08-18 1985-12-31 Tong David Philip Process for the production of alginate fibre material and products made therefrom
EP0227553A2 (en) * 1985-12-26 1987-07-01 Société PRECIS Process for the preparation of a flexible calcium alginate film
FR2592383A1 (en) * 1985-12-26 1987-07-03 Adeline Andre PROCESS FOR THE PREPARATION OF A FLEXIBLE FILM OF CALCIUM ALGINATE
EP0227553A3 (en) * 1985-12-26 1989-03-08 Societe Precis Process for the preparation of a flexible calcium alginate film
US4793337A (en) * 1986-11-17 1988-12-27 E. R. Squibb & Sons, Inc. Adhesive structure and products including same
US5197945A (en) * 1988-05-31 1993-03-30 Minnesota Mining And Manufacturing Company Alginate wound dressing of good integrity
US5238685A (en) * 1988-08-31 1993-08-24 Britcair Limited Wound dressing
WO1990001954A1 (en) * 1988-08-31 1990-03-08 Britcair Limited Wound dressing
EP0380253A3 (en) * 1989-01-24 1990-10-10 Minnesota Mining And Manufacturing Company Alginate hydrogel foam wound dressing
US5230853A (en) * 1990-04-23 1993-07-27 Merck & Co., Inc. Process for making polysaccharide fibers
EP0476756A1 (en) 1990-09-17 1992-03-25 Cv Laboratories Limited Improved absorbency alginate fabric and a method for its preparation
US5256477A (en) * 1990-09-17 1993-10-26 Britcair Limited Absorbency alginate fabric, use as wound and burn dressings, and a method for its preparation
US5840777A (en) * 1992-06-19 1998-11-24 Albany International Corp. Method of producing polysaccharide foams
US5292525A (en) * 1992-10-14 1994-03-08 Merck & Co., Inc. Method and composition for removing an alginate from a cutaneous substrate
WO1996014453A1 (en) * 1994-11-02 1996-05-17 E.R. Squibb & Sons Inc. Alginate ropes, method of preparation and use
FR2755613A1 (en) * 1996-11-13 1998-05-15 Precis DRESSING MATERIAL HAVING CALCIUM ALGINATE MATRIX AND PROCESS FOR PRODUCING THE SAME
EP0845271A1 (en) * 1996-11-13 1998-06-03 Société Précis Dressing material having a calcium alginate matrix and method of making the same
US5981821A (en) * 1996-11-13 1999-11-09 Societe Precis Dressing product with a calcium alginate matrix and method of production of the same
AU734555B2 (en) * 1996-11-13 2001-06-14 Societe Precis Dressing product with a calcium alginate matrix and method of production of the same
CN105755578A (en) * 2015-12-25 2016-07-13 青岛海之林生物科技开发有限公司 Application and preparation method of water-soluble calcium alginate fibers

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