GB575612A - Improvements in and relating to analytical compositions in tablet form - Google Patents
Improvements in and relating to analytical compositions in tablet formInfo
- Publication number
- GB575612A GB575612A GB16740/42A GB1674042A GB575612A GB 575612 A GB575612 A GB 575612A GB 16740/42 A GB16740/42 A GB 16740/42A GB 1674042 A GB1674042 A GB 1674042A GB 575612 A GB575612 A GB 575612A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- tablet
- sodium
- water
- tartaric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 8
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 4
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 4
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 4
- 239000011975 tartaric acid Substances 0.000 abstract 4
- 235000002906 tartaric acid Nutrition 0.000 abstract 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000003513 alkali Substances 0.000 abstract 3
- 239000003518 caustics Substances 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 239000001569 carbon dioxide Substances 0.000 abstract 2
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 2
- 150000001860 citric acid derivatives Chemical class 0.000 abstract 2
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 238000012360 testing method Methods 0.000 abstract 2
- PXRKCOCTEMYUEG-UHFFFAOYSA-N 5-aminoisoindole-1,3-dione Chemical compound NC1=CC=C2C(=O)NC(=O)C2=C1 PXRKCOCTEMYUEG-UHFFFAOYSA-N 0.000 abstract 1
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 abstract 1
- 150000008041 alkali metal carbonates Chemical class 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 210000003567 ascitic fluid Anatomy 0.000 abstract 1
- -1 ascitic fluid Substances 0.000 abstract 1
- 235000013405 beer Nutrition 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-M bisulphate group Chemical group S([O-])(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000013098 chemical test method Methods 0.000 abstract 1
- 235000015165 citric acid Nutrition 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 229940071207 sesquicarbonate Drugs 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 235000017550 sodium carbonate Nutrition 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
Abstract
575,612. Chemical testing. MILES LABORATORIES, INC. Nov. 25, 1942, No. 16740. Convention date, June 19. [Class 1 (i)] An analytical composition in tablet form for testing liquids contains solid caustic alkali in quantity more than sufficient to neutralize the acid content of the tablet, and to provide an alkaline solution on dissolution in water, and a compatible effervescent couple for generating carbon dioxide in the presence of water, and comprising a solid acidic element such as citric acid, tartaric acid and alkali metal, acid citrates or bisulphates, and a solid alkali metal carbonate, sesquicarbonate or bicarbonate. The carbon dioxide liberated when the tablet is added to water or aqueous fluids such as urine, cerebrospinal fluid, blood, ascitic fluid, milk and beer, causes disintegration and prevents the formation of a film by precipitation or coagulation of substances in the fluids such as albumin, mucin and phosphates due to the alkalinity or heat produced. A tablet for detecting reducing sugars in water solutions contains cupric sulphate, citric or tartaric acid or acid citrates, sodium or other alkali metal hydroxide and an effervescent couple composed, for example, of citric acid and sodium bicarbonate or tartaric acid and sodium carbonate. The caustic alkali is used for its heat of solution and reaction with the acid component which is in excess of that required for the effervescent couple. The temperature required for reduction of the copper is thereby produced as well as the necessary alkalinity. A tablet for detecting acetone contains salicylaldehyde-sodium bisulphite, sodium hydroxide, tartaric acid, and sodium carbonate. The caustic alkali content is determined by the amount of fluid and type of test.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US447706A US2387244A (en) | 1942-06-19 | 1942-06-19 | Tablet and method of dissolving same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB575612A true GB575612A (en) | 1946-02-26 |
Family
ID=23777403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB16740/42A Expired GB575612A (en) | 1942-06-19 | 1942-11-25 | Improvements in and relating to analytical compositions in tablet form |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US2387244A (en) |
| GB (1) | GB575612A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1197250B (en) * | 1956-04-12 | 1965-07-22 | Miles Lab | Diagnostic tablet for the determination of albumin |
| US3472626A (en) * | 1965-10-28 | 1969-10-14 | Miles Lab | Test composition and process for detecting organic polyhalogen compounds |
| US3847547A (en) * | 1972-11-24 | 1974-11-12 | France Etat | Process and apparatus for detecting of the presence of a liquid |
| GB2120787A (en) * | 1982-05-26 | 1983-12-07 | Lilly Industries Ltd | Method of estimating feed additives |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2497057A (en) * | 1950-02-07 | Toilet bowl -gleanee | ||
| US2838377A (en) * | 1950-03-09 | 1958-06-10 | Miles Lab | Blood test |
| US2750027A (en) * | 1951-08-21 | 1956-06-12 | Cummings Molly | Visual indicating devices for producing a color slick or patch at sea or in any waters |
| GB708996A (en) * | 1954-04-15 | 1954-05-12 | Miles Lab | Improvements in or relating to diagnostic compositions |
| US2824842A (en) * | 1954-06-09 | 1958-02-25 | Sulkowitch Hirsh | Urine calcium test |
| US2827420A (en) * | 1956-10-24 | 1958-03-18 | Irving B Wershaw | Therapeutic tablets |
| IT586498A (en) * | 1957-04-02 | |||
| US2970945A (en) * | 1958-10-03 | 1961-02-07 | Miles Lab | Diagnostic composition |
| US3131123A (en) * | 1959-03-13 | 1964-04-28 | Lab Francais De Therapeutique | Enteric tablets and manufacture thereof |
| US3120378A (en) * | 1960-02-29 | 1964-02-04 | Procter & Gamble | Bleaching, sterilizing and disinfecting tablet and method of preparation |
| US3310382A (en) * | 1963-02-04 | 1967-03-21 | George R Kingsley | Biuret reagent |
| US3676359A (en) * | 1970-10-14 | 1972-07-11 | Us Navy | Chemical sea surface marker |
| US4956300A (en) * | 1982-01-05 | 1990-09-11 | Helena Laboratories Corporation | Aid for determining the presence of occult blood, method of making the aid, and method of using the aid |
| US4588696A (en) * | 1983-02-17 | 1986-05-13 | Eskelson Cleamond D | Pellet process for the detection of formaldehyde and/or glutaraldehyde |
| US5702913A (en) * | 1983-12-21 | 1997-12-30 | Helena Laboratories Corporation | Chromgen-reagent test system |
| US5273888A (en) * | 1984-01-16 | 1993-12-28 | Helena Laboratories Corporation | Chemical test kit and method for determining the presence of blood in a specimen and for verifying the effectiveness of the chemicals |
| CA1249333A (en) | 1985-06-28 | 1989-01-24 | James E. Jones | Electrochemical sensor and membrane therefor |
| US5081040A (en) * | 1987-06-29 | 1992-01-14 | Helena Laboratories Corporation | Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes |
| US5196167A (en) * | 1989-04-04 | 1993-03-23 | Helena Laboratories Corporation | Fecal occult blood test product with positive and negative controls |
| US5217874A (en) * | 1989-04-04 | 1993-06-08 | Helena Laboratories Corporation | Fecal occult blood test product with positive and negative controls |
| US5415809A (en) * | 1992-07-15 | 1995-05-16 | Aquarium Pharmaceuticals, Inc. | Method for determination of dissolved oxygen in water |
| US7635597B2 (en) | 1995-08-09 | 2009-12-22 | Bayer Healthcare Llc | Dry reagent particle assay and device having multiple test zones and method therefor |
| US7150995B2 (en) | 2004-01-16 | 2006-12-19 | Metrika, Inc. | Methods and systems for point of care bodily fluid analysis |
| EP1816479A4 (en) * | 2004-11-25 | 2009-01-21 | Panasonic Corp | Sensor device |
| US20110318465A1 (en) * | 2010-04-22 | 2011-12-29 | Amerilab Technologies, Inc. | Effervescent carrier, a method of changing the flavor of milk and an effervescent tablet for changing the flavor of milk |
| US10040524B1 (en) | 2017-04-28 | 2018-08-07 | Calvin Collins | Sustained release water marking device for search and rescue |
-
1942
- 1942-06-19 US US447706A patent/US2387244A/en not_active Expired - Lifetime
- 1942-11-25 GB GB16740/42A patent/GB575612A/en not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1197250B (en) * | 1956-04-12 | 1965-07-22 | Miles Lab | Diagnostic tablet for the determination of albumin |
| US3472626A (en) * | 1965-10-28 | 1969-10-14 | Miles Lab | Test composition and process for detecting organic polyhalogen compounds |
| US3847547A (en) * | 1972-11-24 | 1974-11-12 | France Etat | Process and apparatus for detecting of the presence of a liquid |
| GB2120787A (en) * | 1982-05-26 | 1983-12-07 | Lilly Industries Ltd | Method of estimating feed additives |
Also Published As
| Publication number | Publication date |
|---|---|
| US2387244A (en) | 1945-10-23 |
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