GB562314A - Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene - Google Patents

Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene

Info

Publication number
GB562314A
GB562314A GB1822142A GB1822142A GB562314A GB 562314 A GB562314 A GB 562314A GB 1822142 A GB1822142 A GB 1822142A GB 1822142 A GB1822142 A GB 1822142A GB 562314 A GB562314 A GB 562314A
Authority
GB
United Kingdom
Prior art keywords
carbethoxy
tetrahydrothiophene
keto
alkyl
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1822142A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANTHONY WILLIAM D AUBIGNY AVIS
Roche Products Ltd
Original Assignee
ANTHONY WILLIAM D AUBIGNY AVIS
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANTHONY WILLIAM D AUBIGNY AVIS, Roche Products Ltd filed Critical ANTHONY WILLIAM D AUBIGNY AVIS
Priority to GB1822142A priority Critical patent/GB562314A/en
Publication of GB562314A publication Critical patent/GB562314A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the formula:- <FORM:0562314/IV/1> where R1 is an alkyl group and R2 is an alkyl or substituted alkyl or fatty acid ester group are prepared by reacting compounds of the formula:- <FORM:0562314/IV/2> which can be prepared by the process described and claimed in Specification 562,313, with an alkyl or substituted alkyl halide or halogenated fatty acid ester in the presence of an alkaline condensing agent such as sodium ethylate. In examples: (1) 2-carbethoxy-3-keto-tetrahydrothiophene, prepared as in Specification 562,313 is treated, in the presence of sodium ethylate, with b -iodopropionic ethyl ester. The product is acidified, extracted with ester, washed, dried, and distilled under reduced pressure to yield 2 - carbethoxy - 2 - (b - carbethoxyethyl) - 3 - keto - tetrahydrothiophene; (2) in analogous manner using #s-iodopropylmalonic ethyl ester there is obtained 2 - carbethoxy - 2 - (#s - dicarbethoxy butyl)-3-keto-tetrahydrothiophene.
GB1822142A 1942-12-22 1942-12-22 Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene Expired GB562314A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1822142A GB562314A (en) 1942-12-22 1942-12-22 Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1822142A GB562314A (en) 1942-12-22 1942-12-22 Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene

Publications (1)

Publication Number Publication Date
GB562314A true GB562314A (en) 1944-06-27

Family

ID=10108728

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1822142A Expired GB562314A (en) 1942-12-22 1942-12-22 Process for the manufacture of substituted derivatives of 3-ketotetrahydrothiophene

Country Status (1)

Country Link
GB (1) GB562314A (en)

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