GB478246A - Improvements in or relating to the manufacture of organic acids and esters - Google Patents
Improvements in or relating to the manufacture of organic acids and estersInfo
- Publication number
- GB478246A GB478246A GB19464/36A GB1946436A GB478246A GB 478246 A GB478246 A GB 478246A GB 19464/36 A GB19464/36 A GB 19464/36A GB 1946436 A GB1946436 A GB 1946436A GB 478246 A GB478246 A GB 478246A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reaction
- atmos
- acid
- alcohols
- carbon monoxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
- C07C51/12—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide on an oxygen-containing group in organic compounds, e.g. alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/36—Preparation of carboxylic acid esters by reaction with carbon monoxide or formates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Carboxylic acids and esters are made by reaction of a saturated monohydric aliphatic alcohol with carbon monoxide in the presence of a boron halide, e.g. boron fluoride, the reaction when carried out in the liquid phase being effected substantially in the absence of water. The reaction may be effected in the liquid phase from room temperature up to about 350 DEG C., preferably 180--240 DEG C., and from atmospheric pressure up to 1000 atmos. or more, preferably 350--750 atmos., or in the vapour phase, preferably at 200--400 DEG C., and at 25--900, preferably 350--700 atmos. Substances promoting the activity of the condensing agent such as metals or metal oxides, e.g. nickel or nickel oxide, may be present. The vapour phase reaction is advantageously carried out in the presence of water vapour. The reactant vapours may be led over activated charcoal. Carbon monoxide from commercial sources may be used, preferably after removal of sulphur compounds, metal carbonyls and like impurities but containing inert gases such as nitrogen. Suitable alcohols comprise methyl, ethyl, propyl, butyl, including the secondary and tertiary alcohols, hexyl, and octyl alcohols. The reaction apparatus may be of acid-resisting alloy steels or chromium or silver plated inside. In examples: (1) boron fluoride is absorbed in a molecularly equivalent weight of methanol in an autoclave. Carbon monoxide is added till the pressure is 700 atmos. and temperature maintained at 200 DEG C. to form acetic acid; (2) ethanol similarly gives propionic acid; (3) a gaseous mixture containing 85 per cent by volume of CO, and 5 per cent each of C2H5OH, H2O, and H2, is passed with about 2 per cent BF3 over activated charcoal at about 325 DEG C. and 700 atm. to yield acetic acid. Specification 310,438, [Class 2 (iii)], is referred to. The Specification as open to inspection under Sect. 91 comprises the use as condensing agents of hydrofluoboric acid or oxygenated acids obtained by reacting HF with boric acid or borates, e.g. as described in Specification 478,085, [Group III]. It includes also the preparation of polycarboxylic acids from polyhydroxy alcohols such as ethylene or propylene glycol or glycerine. This subject-matter does not appear in the Specification as accepted.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US478246XA | 1935-07-13 | 1935-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB478246A true GB478246A (en) | 1938-01-13 |
Family
ID=21951189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB19464/36A Expired GB478246A (en) | 1935-07-13 | 1936-07-13 | Improvements in or relating to the manufacture of organic acids and esters |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB478246A (en) |
-
1936
- 1936-07-13 GB GB19464/36A patent/GB478246A/en not_active Expired
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