Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20618/33A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
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Filing date
Publication date
Application filed by Sandoz AGfiledCriticalSandoz AG
Publication of GB406197ApublicationCriticalpatent/GB406197A/en
Glucosides of therapeutic value are obtained by eliminating the acetyl groups present in glucosides derived from digitalis lanata by treatment with alkaline agents, e.g. alkali metal hydroxides and carbonates, alkaline earth metal hydroxides and carbonates or disodium phosphate, in presence of water. Among the glucosides mentioned as starting materials are those prepared according to Specifications 370,344 and 405,890. Organic solvents miscible with water may be present during the disacetylation process, e.g. methanol, ethanol, acetone, dioxane, pyridine and glycol monomethylether. The alkaline agent is preferably used in equivalent quantity and temperatures of 10--40 DEG C. employed. Examples are given, and the properties of the products described.
GB20618/33A1932-07-221933-07-21A process for the manufacture of new cardio-active glucosides from digitalis lanata
ExpiredGB406197A
(en)