GB310934A - Process for the manufacture of preparations of insulin - Google Patents

Process for the manufacture of preparations of insulin

Info

Publication number
GB310934A
GB310934A GB13727/29A GB1372729A GB310934A GB 310934 A GB310934 A GB 310934A GB 13727/29 A GB13727/29 A GB 13727/29A GB 1372729 A GB1372729 A GB 1372729A GB 310934 A GB310934 A GB 310934A
Authority
GB
United Kingdom
Prior art keywords
acid
hippuric
insulin
formaldehyde
methylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13727/29A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KARL EDUARD ZIPF
Original Assignee
KARL EDUARD ZIPF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KARL EDUARD ZIPF filed Critical KARL EDUARD ZIPF
Publication of GB310934A publication Critical patent/GB310934A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

310,934. Zipf, K. E. May 3, 1938, [Convention date]. Void [Published under Sect. 91 of the Acts]. Medicines for internal use.-Preparations of insulin suitable to be administered by the mouth are obtained by mixing insulin, or organs or preparations of organs containing it, with an organic acid, or a salt thereof, or an agent yielding acid or splitting off formaldehyde, or a mixture of such substances. The preparations are put up in hardened gelatine capsules or as coated pills so as to be protected against gastric digestion. Acids specified are the fatty acids, and benzoic, hippuric, methylene hippuric, glutaric, glutaminic, mandelic, and cinnamic acids; agents yielding acids are acid esters and acid amides such as fats and formamide: agents yielding formaldehyde are methylene hippuric acid, hexamethylene tetramine, methylene citric acid, para-formaldehyde, and trioxymethylene. According to examples dry insulin is mixed respectively with (1) hippuric acid and sodium hippurate, (2) methylene hippuric acid, and (3) benzoic acid, para-formaldehyde, sodium hippurate, and glutaminic acid. The prior use of mixtures of insulin with inorganic acid is referred to.
GB13727/29A 1928-05-03 1929-05-02 Process for the manufacture of preparations of insulin Expired GB310934A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE310934X 1928-05-03

Publications (1)

Publication Number Publication Date
GB310934A true GB310934A (en) 1930-02-06

Family

ID=6126953

Family Applications (1)

Application Number Title Priority Date Filing Date
GB13727/29A Expired GB310934A (en) 1928-05-03 1929-05-02 Process for the manufacture of preparations of insulin

Country Status (1)

Country Link
GB (1) GB310934A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres

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