GB2602268B - Time-resolved fluorescence reader and method - Google Patents

Time-resolved fluorescence reader and method Download PDF

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Publication number
GB2602268B
GB2602268B GB2020123.2A GB202020123A GB2602268B GB 2602268 B GB2602268 B GB 2602268B GB 202020123 A GB202020123 A GB 202020123A GB 2602268 B GB2602268 B GB 2602268B
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United Kingdom
Prior art keywords
time
resolved fluorescence
fluorescence reader
reader
resolved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2020123.2A
Other versions
GB2602268A (en
GB202020123D0 (en
Inventor
Adsul Neeraj
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forsite Diagnostics Ltd
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Forsite Diagnostics Ltd
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Publication date
Application filed by Forsite Diagnostics Ltd filed Critical Forsite Diagnostics Ltd
Priority to GB2020123.2A priority Critical patent/GB2602268B/en
Publication of GB202020123D0 publication Critical patent/GB202020123D0/en
Publication of GB2602268A publication Critical patent/GB2602268A/en
Application granted granted Critical
Publication of GB2602268B publication Critical patent/GB2602268B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251Colorimeters; Construction thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/8483Investigating reagent band
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7786Fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
GB2020123.2A 2020-12-18 2020-12-18 Time-resolved fluorescence reader and method Active GB2602268B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2020123.2A GB2602268B (en) 2020-12-18 2020-12-18 Time-resolved fluorescence reader and method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2020123.2A GB2602268B (en) 2020-12-18 2020-12-18 Time-resolved fluorescence reader and method

Publications (3)

Publication Number Publication Date
GB202020123D0 GB202020123D0 (en) 2021-02-03
GB2602268A GB2602268A (en) 2022-06-29
GB2602268B true GB2602268B (en) 2022-12-14

Family

ID=74221375

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2020123.2A Active GB2602268B (en) 2020-12-18 2020-12-18 Time-resolved fluorescence reader and method

Country Status (1)

Country Link
GB (1) GB2602268B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001058A1 (en) * 1986-08-06 1988-02-11 Roger Philip Ekins Determination of analyte concentration using two labelling markers
WO2004021004A1 (en) * 2002-08-27 2004-03-11 Kimberly-Clark Worldwide, Inc. Membrane-based assays using time-resolved fluorescence
US20090289201A1 (en) * 2008-05-20 2009-11-26 Rapid Pathogen Screening, Inc. Combined visual/fluorescence analyte detection test
WO2012012499A1 (en) * 2010-07-20 2012-01-26 Nurx Pharmaceuticals, Inc. Optical reader system
WO2015085186A1 (en) * 2013-12-06 2015-06-11 President And Fellows Of Harvard College Electronic reader
US20190376966A1 (en) * 2018-06-06 2019-12-12 Reliant Immune Diagnostics, Inc. System and method for remote colorimetry and ratiometric comparison and quantification in analysis of medical test results

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001058A1 (en) * 1986-08-06 1988-02-11 Roger Philip Ekins Determination of analyte concentration using two labelling markers
WO2004021004A1 (en) * 2002-08-27 2004-03-11 Kimberly-Clark Worldwide, Inc. Membrane-based assays using time-resolved fluorescence
US20090289201A1 (en) * 2008-05-20 2009-11-26 Rapid Pathogen Screening, Inc. Combined visual/fluorescence analyte detection test
WO2012012499A1 (en) * 2010-07-20 2012-01-26 Nurx Pharmaceuticals, Inc. Optical reader system
WO2015085186A1 (en) * 2013-12-06 2015-06-11 President And Fellows Of Harvard College Electronic reader
US20190376966A1 (en) * 2018-06-06 2019-12-12 Reliant Immune Diagnostics, Inc. System and method for remote colorimetry and ratiometric comparison and quantification in analysis of medical test results

Also Published As

Publication number Publication date
GB2602268A (en) 2022-06-29
GB202020123D0 (en) 2021-02-03

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