GB2597145B - Compound separated from root bark of Ginkgo biloba and use thereof - Google Patents

Compound separated from root bark of Ginkgo biloba and use thereof Download PDF

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Publication number
GB2597145B
GB2597145B GB2112782.4A GB202112782A GB2597145B GB 2597145 B GB2597145 B GB 2597145B GB 202112782 A GB202112782 A GB 202112782A GB 2597145 B GB2597145 B GB 2597145B
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GB
United Kingdom
Prior art keywords
ginkgo biloba
root bark
compound separated
compound
separated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2112782.4A
Other languages
English (en)
Other versions
GB202112782D0 (en
GB2597145A (en
Inventor
Yao Jianbiao
Wang Ruwei
Jin Huihui
Ding Nan
Wu Hualing
Ping Xiating
Zha Huijun
He Houhong
Wu Jian
Wang Jianfang
Tan Linwei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHEJIANG CONBA PHARMACEUTICAL CO Ltd
Zhejiang Conba Pharm Co Ltd
Original Assignee
ZHEJIANG CONBA PHARMACEUTICAL CO Ltd
Zhejiang Conba Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZHEJIANG CONBA PHARMACEUTICAL CO Ltd, Zhejiang Conba Pharm Co Ltd filed Critical ZHEJIANG CONBA PHARMACEUTICAL CO Ltd
Publication of GB202112782D0 publication Critical patent/GB202112782D0/en
Publication of GB2597145A publication Critical patent/GB2597145A/en
Application granted granted Critical
Publication of GB2597145B publication Critical patent/GB2597145B/en
Active legal-status Critical Current
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91Dibenzofurans; Hydrogenated dibenzofurans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/34Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/88Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/884Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Medicines Containing Plant Substances (AREA)
GB2112782.4A 2019-03-29 2019-10-28 Compound separated from root bark of Ginkgo biloba and use thereof Active GB2597145B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910249522.8A CN111747914B (zh) 2019-03-29 2019-03-29 一种银杏根皮中分离得到的化合物及其用途
PCT/CN2019/113565 WO2020199568A1 (zh) 2019-03-29 2019-10-28 一种银杏根皮中分离得到的化合物及其用途

Publications (3)

Publication Number Publication Date
GB202112782D0 GB202112782D0 (en) 2021-10-20
GB2597145A GB2597145A (en) 2022-01-19
GB2597145B true GB2597145B (en) 2022-06-15

Family

ID=72664811

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2112782.4A Active GB2597145B (en) 2019-03-29 2019-10-28 Compound separated from root bark of Ginkgo biloba and use thereof

Country Status (3)

Country Link
CN (1) CN111747914B (zh)
GB (1) GB2597145B (zh)
WO (1) WO2020199568A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113899840B (zh) * 2021-11-08 2023-05-12 黑龙江珍宝岛药业股份有限公司 一种银杏叶提取中间体或银杏叶制剂的木脂素类成分指纹图谱的建立方法及其应用
CN115006435B (zh) * 2022-06-21 2023-11-28 浙江康恩贝制药股份有限公司 一种银杏叶有机酸提取物及其制备方法和用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102174052A (zh) * 2011-03-23 2011-09-07 晨光生物科技集团天津有限公司 一种银杏内酯的提取精制方法
CN102199159A (zh) * 2011-03-21 2011-09-28 贵州大学 从银杏根皮中分离、纯化银杏内酯c的方法
CN103610708A (zh) * 2013-11-19 2014-03-05 浙江康恩贝制药股份有限公司 一种银杏根皮中低酸高纯度萜内酯提取物的制备工艺

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102199159A (zh) * 2011-03-21 2011-09-28 贵州大学 从银杏根皮中分离、纯化银杏内酯c的方法
CN102174052A (zh) * 2011-03-23 2011-09-07 晨光生物科技集团天津有限公司 一种银杏内酯的提取精制方法
CN103610708A (zh) * 2013-11-19 2014-03-05 浙江康恩贝制药股份有限公司 一种银杏根皮中低酸高纯度萜内酯提取物的制备工艺

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
(ZHAO, Jinlong et al.). "(I) (Chemical constituents from root barks of Ginkgo biloba (I))" (Chinese Tradional and Herbal Drugs), Vol. 44, No. 10, 31 May 2013 (2013-05-31) ISSN: 0253-2670, pp. 1245-1247 *
WEI, Xueli et al. "A NEW LIGNAN FROM THE ROOTS OF Ginkgo biloba" Chemistry of Natural Compounds, Vol. 51, No. 5, 30 September 2015 (2015-09-30), ISSN: 1573-8388, pp. 819-821 *

Also Published As

Publication number Publication date
GB202112782D0 (en) 2021-10-20
CN111747914A (zh) 2020-10-09
CN111747914B (zh) 2023-01-13
WO2020199568A1 (zh) 2020-10-08
GB2597145A (en) 2022-01-19

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