GB2586339B - Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity - Google Patents

Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity Download PDF

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Publication number
GB2586339B
GB2586339B GB2009861.2A GB202009861A GB2586339B GB 2586339 B GB2586339 B GB 2586339B GB 202009861 A GB202009861 A GB 202009861A GB 2586339 B GB2586339 B GB 2586339B
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United Kingdom
Prior art keywords
sensing
molecular entity
current
measuring
measurement apparatus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB2009861.2A
Other versions
GB2586339A (en
GB202009861D0 (en
Inventor
Fish David
Veenstra Hugo
Totey Emil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Nanopore Technologies PLC
Original Assignee
Oxford Nanopore Technologies PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Nanopore Technologies PLC filed Critical Oxford Nanopore Technologies PLC
Priority to GB2009861.2A priority Critical patent/GB2586339B/en
Priority claimed from GB1903742.3A external-priority patent/GB2580988B/en
Publication of GB202009861D0 publication Critical patent/GB202009861D0/en
Publication of GB2586339A publication Critical patent/GB2586339A/en
Application granted granted Critical
Publication of GB2586339B publication Critical patent/GB2586339B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R19/00—Arrangements for measuring currents or voltages or for indicating presence or sign thereof
    • G01R19/0046—Arrangements for measuring currents or voltages or for indicating presence or sign thereof characterised by a specific application or detail not covered by any other subgroup of G01R19/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R19/00—Arrangements for measuring currents or voltages or for indicating presence or sign thereof
    • G01R19/0023—Measuring currents or voltages from sources with high internal resistance by means of measuring circuits with high input impedance, e.g. OP-amplifiers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
    • G01N27/228—Circuits therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R15/00—Details of measuring arrangements of the types provided for in groups G01R17/00 - G01R29/00, G01R33/00 - G01R33/26 or G01R35/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R19/00—Arrangements for measuring currents or voltages or for indicating presence or sign thereof
    • G01R19/0046—Arrangements for measuring currents or voltages or for indicating presence or sign thereof characterised by a specific application or detail not covered by any other subgroup of G01R19/00
    • G01R19/0053—Noise discrimination; Analog sampling; Measuring transients

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Transforming Light Signals Into Electric Signals (AREA)
GB2009861.2A 2019-03-19 2019-03-19 Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity Active GB2586339B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2009861.2A GB2586339B (en) 2019-03-19 2019-03-19 Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2009861.2A GB2586339B (en) 2019-03-19 2019-03-19 Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity
GB1903742.3A GB2580988B (en) 2019-03-19 2019-03-19 Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity

Publications (3)

Publication Number Publication Date
GB202009861D0 GB202009861D0 (en) 2020-08-12
GB2586339A GB2586339A (en) 2021-02-17
GB2586339B true GB2586339B (en) 2021-12-01

Family

ID=71949914

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2009861.2A Active GB2586339B (en) 2019-03-19 2019-03-19 Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity

Country Status (1)

Country Link
GB (1) GB2586339B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011067559A1 (en) * 2009-12-01 2011-06-09 Oxford Nanopore Technologies Limited Biochemical analysis instrument
US20150001097A1 (en) * 2013-06-27 2015-01-01 Lifescan Scotland Limited Temperature compensation for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte
US20150265994A1 (en) * 2012-10-26 2015-09-24 Oxford Nanopore Technologies Ltd. Formation of array of membranes and apparatus therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011067559A1 (en) * 2009-12-01 2011-06-09 Oxford Nanopore Technologies Limited Biochemical analysis instrument
US20150265994A1 (en) * 2012-10-26 2015-09-24 Oxford Nanopore Technologies Ltd. Formation of array of membranes and apparatus therefor
US20150001097A1 (en) * 2013-06-27 2015-01-01 Lifescan Scotland Limited Temperature compensation for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte

Also Published As

Publication number Publication date
GB2586339A (en) 2021-02-17
GB202009861D0 (en) 2020-08-12

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