GB2553398B - Analysis of isomers in TIMS-Q-q TOF mass spectrometers - Google Patents

Analysis of isomers in TIMS-Q-q TOF mass spectrometers Download PDF

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Publication number
GB2553398B
GB2553398B GB1708656.2A GB201708656A GB2553398B GB 2553398 B GB2553398 B GB 2553398B GB 201708656 A GB201708656 A GB 201708656A GB 2553398 B GB2553398 B GB 2553398B
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GB
United Kingdom
Prior art keywords
tims
isomers
analysis
tof mass
mass spectrometers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1708656.2A
Other versions
GB201708656D0 (en
GB2553398A (en
Inventor
Harder Alexander
Lubeck Markus
Meyer Sven
Suckau Detlev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Daltonics GmbH and Co KG
Original Assignee
Bruker Daltonics GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102017111067.4A external-priority patent/DE102017111067B4/en
Application filed by Bruker Daltonics GmbH and Co KG filed Critical Bruker Daltonics GmbH and Co KG
Priority to GB2205043.9A priority Critical patent/GB2602769B/en
Publication of GB201708656D0 publication Critical patent/GB201708656D0/en
Publication of GB2553398A publication Critical patent/GB2553398A/en
Application granted granted Critical
Publication of GB2553398B publication Critical patent/GB2553398B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/623—Ion mobility spectrometry combined with mass spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1708656.2A 2016-06-02 2017-05-31 Analysis of isomers in TIMS-Q-q TOF mass spectrometers Active GB2553398B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2205043.9A GB2602769B (en) 2016-06-02 2017-05-31 Analysis of Isomers in TIMS-Q-q-TOF Mass Spectrometers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102016110165 2016-06-02
DE102017111067.4A DE102017111067B4 (en) 2016-06-02 2017-05-22 Isomer analysis in TIMS-Q-q-TOF mass spectrometers

Publications (3)

Publication Number Publication Date
GB201708656D0 GB201708656D0 (en) 2017-07-12
GB2553398A GB2553398A (en) 2018-03-07
GB2553398B true GB2553398B (en) 2022-06-08

Family

ID=59270937

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1708656.2A Active GB2553398B (en) 2016-06-02 2017-05-31 Analysis of isomers in TIMS-Q-q TOF mass spectrometers
GB2205043.9A Active GB2602769B (en) 2016-06-02 2017-05-31 Analysis of Isomers in TIMS-Q-q-TOF Mass Spectrometers

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2205043.9A Active GB2602769B (en) 2016-06-02 2017-05-31 Analysis of Isomers in TIMS-Q-q-TOF Mass Spectrometers

Country Status (2)

Country Link
CN (1) CN115711934A (en)
GB (2) GB2553398B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018124203B4 (en) 2018-10-01 2022-05-25 Bruker Daltonics GmbH & Co. KG Determination of the reduced ion mobility of an ion species by stored ion mobility spectrometry (TIMS)
GB2587249B (en) * 2019-04-15 2023-11-08 Bruker Daltonics Gmbh & Co Kg A method for controlling the mass filter in a hybrid IMS/MS system
EP3945314B1 (en) 2020-07-31 2022-10-26 Bruker Daltonics GmbH & Co. KG Method and apparatus for data independent combined ion mobility and mass spectroscopy analysis

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000070335A2 (en) * 1999-05-17 2000-11-23 Advanced Research & Technology Institute Ion mobility and mass spectrometer
US20120273670A1 (en) * 2011-04-26 2012-11-01 Bruker Daltonik Gmbh Spectrum Acquisition Modes For Ion Mobility Spectrometers Using Trapped Ions
WO2013140132A2 (en) * 2012-03-22 2013-09-26 Micromass Uk Limited Multi-dimensional survey scans for improved data dependent acquisitions
US20130277548A1 (en) * 2012-03-12 2013-10-24 Micromass Uk Limited Method Of Mass Spectrometry And A Mass Spectrometer
US20130299690A1 (en) * 2012-05-14 2013-11-14 Battelle Memorial Institute Method for enhancing the resolving power of ion mobility separations over a limited mobility range
WO2015189545A1 (en) * 2014-06-11 2015-12-17 Micromass Uk Limited Ion mobility spectrometry data directed acquisition
EP3165914A1 (en) * 2015-11-03 2017-05-10 Bruker Daltonik GmbH Acquisition of fragment ion mass spectra of ions separated by their mobility

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000070335A2 (en) * 1999-05-17 2000-11-23 Advanced Research & Technology Institute Ion mobility and mass spectrometer
US20120273670A1 (en) * 2011-04-26 2012-11-01 Bruker Daltonik Gmbh Spectrum Acquisition Modes For Ion Mobility Spectrometers Using Trapped Ions
US20130277548A1 (en) * 2012-03-12 2013-10-24 Micromass Uk Limited Method Of Mass Spectrometry And A Mass Spectrometer
WO2013140132A2 (en) * 2012-03-22 2013-09-26 Micromass Uk Limited Multi-dimensional survey scans for improved data dependent acquisitions
US20130299690A1 (en) * 2012-05-14 2013-11-14 Battelle Memorial Institute Method for enhancing the resolving power of ion mobility separations over a limited mobility range
WO2015189545A1 (en) * 2014-06-11 2015-12-17 Micromass Uk Limited Ion mobility spectrometry data directed acquisition
EP3165914A1 (en) * 2015-11-03 2017-05-10 Bruker Daltonik GmbH Acquisition of fragment ion mass spectra of ions separated by their mobility

Also Published As

Publication number Publication date
GB2602769A (en) 2022-07-13
CN115711934A (en) 2023-02-24
GB2602769A9 (en) 2022-07-20
GB201708656D0 (en) 2017-07-12
GB202205043D0 (en) 2022-05-18
GB2602769B (en) 2022-10-05
GB2553398A (en) 2018-03-07

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