GB2539857B - Devices and methods for purification, detection and use of biological cells - Google Patents
Devices and methods for purification, detection and use of biological cells Download PDFInfo
- Publication number
- GB2539857B GB2539857B GB1618356.8A GB201618356A GB2539857B GB 2539857 B GB2539857 B GB 2539857B GB 201618356 A GB201618356 A GB 201618356A GB 2539857 B GB2539857 B GB 2539857B
- Authority
- GB
- United Kingdom
- Prior art keywords
- purification
- detection
- methods
- devices
- biological cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/428—Frontal mode
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/166—Fluid composition conditioning, e.g. gradient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/422—Displacement mode
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2102155.5A GB2587768B (en) | 2014-04-03 | 2015-04-03 | Devices and methods for purification, detection and use of biological cells |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461974950P | 2014-04-03 | 2014-04-03 | |
US201462061636P | 2014-10-08 | 2014-10-08 | |
PCT/US2015/024374 WO2015154048A1 (en) | 2014-04-03 | 2015-04-03 | Devices and methods for purification, detection and use of biological cells |
Publications (3)
Publication Number | Publication Date |
---|---|
GB201618356D0 GB201618356D0 (en) | 2016-12-14 |
GB2539857A GB2539857A (en) | 2016-12-28 |
GB2539857B true GB2539857B (en) | 2021-03-31 |
Family
ID=54241352
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1618356.8A Active GB2539857B (en) | 2014-04-03 | 2015-04-03 | Devices and methods for purification, detection and use of biological cells |
GB2102155.5A Active GB2587768B (en) | 2014-04-03 | 2015-04-03 | Devices and methods for purification, detection and use of biological cells |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2102155.5A Active GB2587768B (en) | 2014-04-03 | 2015-04-03 | Devices and methods for purification, detection and use of biological cells |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3126027A4 (en) |
GB (2) | GB2539857B (en) |
WO (1) | WO2015154048A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201521784D0 (en) * | 2015-12-10 | 2016-01-27 | Univ Birmingham | Cell purification |
CA3123030C (en) * | 2018-10-09 | 2023-04-04 | C Technologies, Inc. | Mass control system for chromatography |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215927A (en) * | 1986-01-30 | 1993-06-01 | Fred Hutchinson Cancer Research Center | Method for immunoselection of cells using avidin and biotin |
US6362008B1 (en) * | 1997-12-23 | 2002-03-26 | Barbara A. Kohn | Generic signalling mechanism for detection of analytes |
US20040121382A1 (en) * | 2002-12-18 | 2004-06-24 | Linda Liu | Multiplexed immunohistochemical assays using molecular tags |
WO2013124474A2 (en) * | 2012-02-23 | 2013-08-29 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
WO2014001326A1 (en) * | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof |
US20140234890A1 (en) * | 2013-02-15 | 2014-08-21 | Douglas T. Gjerde | Methods for Purifying Biological Cells |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5773224A (en) * | 1996-02-12 | 1998-06-30 | Grandics; Peter | Immunoselection system for cell elution |
US20090081084A1 (en) * | 2003-07-14 | 2009-03-26 | Gjerde Douglas T | Low Dead Volume Extraction Column Device |
US8377715B2 (en) * | 2003-07-14 | 2013-02-19 | Phynexus, Inc. | Method and device for sample preparation |
US20100140173A1 (en) * | 2004-12-03 | 2010-06-10 | Chris Suh | Method and Device for Gravity Flow Chromatography |
GB2525562B (en) * | 2013-02-15 | 2017-10-11 | T Gjerde Douglas | Methods for purification of biological cells |
-
2015
- 2015-04-03 WO PCT/US2015/024374 patent/WO2015154048A1/en active Application Filing
- 2015-04-03 EP EP15773853.5A patent/EP3126027A4/en not_active Withdrawn
- 2015-04-03 GB GB1618356.8A patent/GB2539857B/en active Active
- 2015-04-03 GB GB2102155.5A patent/GB2587768B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215927A (en) * | 1986-01-30 | 1993-06-01 | Fred Hutchinson Cancer Research Center | Method for immunoselection of cells using avidin and biotin |
US6362008B1 (en) * | 1997-12-23 | 2002-03-26 | Barbara A. Kohn | Generic signalling mechanism for detection of analytes |
US20040121382A1 (en) * | 2002-12-18 | 2004-06-24 | Linda Liu | Multiplexed immunohistochemical assays using molecular tags |
WO2013124474A2 (en) * | 2012-02-23 | 2013-08-29 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
WO2014001326A1 (en) * | 2012-06-27 | 2014-01-03 | F. Hoffmann-La Roche Ag | Method for the selection and production of tailor-made, selective and multi-specific therapeutic molecules comprising at least two different targeting entities and uses thereof |
US20140234890A1 (en) * | 2013-02-15 | 2014-08-21 | Douglas T. Gjerde | Methods for Purifying Biological Cells |
Also Published As
Publication number | Publication date |
---|---|
GB2539857A (en) | 2016-12-28 |
GB2587768A (en) | 2021-04-07 |
GB2587768B (en) | 2021-08-18 |
GB202102155D0 (en) | 2021-03-31 |
GB201618356D0 (en) | 2016-12-14 |
EP3126027A1 (en) | 2017-02-08 |
WO2015154048A1 (en) | 2015-10-08 |
EP3126027A4 (en) | 2017-11-01 |
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