GB2530836B - Hybrid mass spectrometer - Google Patents

Hybrid mass spectrometer

Info

Publication number
GB2530836B
GB2530836B GB1509281.0A GB201509281A GB2530836B GB 2530836 B GB2530836 B GB 2530836B GB 201509281 A GB201509281 A GB 201509281A GB 2530836 B GB2530836 B GB 2530836B
Authority
GB
United Kingdom
Prior art keywords
mass spectrometer
hybrid mass
hybrid
spectrometer
mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1509281.0A
Other versions
GB2530836A (en
GB201509281D0 (en
Inventor
Giles Kevin
J Langridge David
Derek Pringle Steven
George Richardson Keith
Lee Wildgoose Jason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of GB201509281D0 publication Critical patent/GB201509281D0/en
Publication of GB2530836A publication Critical patent/GB2530836A/en
Application granted granted Critical
Publication of GB2530836B publication Critical patent/GB2530836B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0009—Calibration of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
GB1509281.0A 2014-05-30 2015-05-29 Hybrid mass spectrometer Active GB2530836B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1409586.3A GB201409586D0 (en) 2014-05-30 2014-05-30 Hybrid mass spectrometer

Publications (3)

Publication Number Publication Date
GB201509281D0 GB201509281D0 (en) 2015-07-15
GB2530836A GB2530836A (en) 2016-04-06
GB2530836B true GB2530836B (en) 2018-11-07

Family

ID=51214440

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1409586.3A Ceased GB201409586D0 (en) 2014-05-30 2014-05-30 Hybrid mass spectrometer
GB1509281.0A Active GB2530836B (en) 2014-05-30 2015-05-29 Hybrid mass spectrometer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1409586.3A Ceased GB201409586D0 (en) 2014-05-30 2014-05-30 Hybrid mass spectrometer

Country Status (1)

Country Link
GB (2) GB201409586D0 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109075014A (en) * 2016-04-19 2018-12-21 英国质谱公司 Transfer tube calibration
GB201711795D0 (en) * 2017-07-21 2017-09-06 Micromass Ltd Mobility and mass measurement using time - varying electric fields
US20230238232A1 (en) * 2020-05-22 2023-07-27 Dh Technologies Development Pte. Ltd. Identification of a First Sample in a Series of Sequential Samples

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020030159A1 (en) * 1999-05-21 2002-03-14 Igor Chernushevich MS/MS scan methods for a quadrupole/time of flight tandem mass spectrometer
EP1378930A2 (en) * 2002-05-30 2004-01-07 Micromass Limited Mass spectrometer
US20040113064A1 (en) * 2001-05-25 2004-06-17 Katrin Fuhrer Time-of-flight mass spectrometer for monitoring of fast processes
GB2421844A (en) * 2004-12-08 2006-07-05 Micromass Ltd A mass spectrometer comprising an ion guide located downstream of a mass selective ion trap or mass analyser
WO2011027131A1 (en) * 2009-09-04 2011-03-10 Micromass Uk Limited A method of screening a sample for the presence of one or more known compounds of interest and a mass spectrometer performing this method
GB2512738A (en) * 2013-03-06 2014-10-08 Micromass Ltd Optimised ion mobility separation timescales for targeted ions

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020030159A1 (en) * 1999-05-21 2002-03-14 Igor Chernushevich MS/MS scan methods for a quadrupole/time of flight tandem mass spectrometer
US20040113064A1 (en) * 2001-05-25 2004-06-17 Katrin Fuhrer Time-of-flight mass spectrometer for monitoring of fast processes
EP1378930A2 (en) * 2002-05-30 2004-01-07 Micromass Limited Mass spectrometer
GB2421844A (en) * 2004-12-08 2006-07-05 Micromass Ltd A mass spectrometer comprising an ion guide located downstream of a mass selective ion trap or mass analyser
WO2011027131A1 (en) * 2009-09-04 2011-03-10 Micromass Uk Limited A method of screening a sample for the presence of one or more known compounds of interest and a mass spectrometer performing this method
GB2512738A (en) * 2013-03-06 2014-10-08 Micromass Ltd Optimised ion mobility separation timescales for targeted ions

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Analytical Chemistry [online] Vol. 86, 2014, J.C. May et al., "Conformational Ordering of Biomolecules in the Gas Phase: Nitrogen Collision Cross Sections Measured on a Prototype High Resolution Drift Tube Ion Mobility-Mass Spectrometer", From: http://dx.doi.org/10.1021/ac4038448 [Accessed 27/01/16] *
International Journal of Mass Spectrometry [online] Vol. 236, 2 July 2004, K. Thalassinos et al., "Ion mobility mass spectrometry of proteins in a modified commercial mass spectrometer", Available from: http://dx.doi.org/10.1016/j.ijms.2004.05.008 [Accessed 27 Jan 2016] pages 55-63 *
Journal of Chromatography B [online] Vol. 782, 4 October 2002, B. T. Ruotolo et al., "Peak capacity of ion mobility mass spectrometry: Separation of peptides in helium buffer gas", Available from: http://dx.doi.org/10.1016/S1570-0232(02)00566-4 [Accessed 27 Jan 2016] pages 385-392 *
Journal of the American Society for Mass Spectrometry [online] Vol. 18, 2007, S. L. Koeniger et al., "Resolution and Structural Transitions of Elongated States of Ubiquitin", available from: http://dx.doi.org/10.1016/j.jasms.2006.09.025 [Accessed 01/12/2016] pages 322-331. *

Also Published As

Publication number Publication date
GB201409586D0 (en) 2014-07-16
GB2530836A (en) 2016-04-06
GB201509281D0 (en) 2015-07-15

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