GB2497899B - Sanguiin for use in the prevention or treatment of bone marrow inhibition - Google Patents

Sanguiin for use in the prevention or treatment of bone marrow inhibition

Info

Publication number
GB2497899B
GB2497899B GB1306569.3A GB201306569A GB2497899B GB 2497899 B GB2497899 B GB 2497899B GB 201306569 A GB201306569 A GB 201306569A GB 2497899 B GB2497899 B GB 2497899B
Authority
GB
United Kingdom
Prior art keywords
sanguiin
prevention
treatment
bone marrow
marrow inhibition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1306569.3A
Other versions
GB2497899A (en
GB201306569D0 (en
Inventor
Yang Ming
Su Zhetong
Yang Sheng
Wang Dabin
Zou Wenquan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHENGDU KEER PHARMACEUTICAL CO Ltd
Original Assignee
CHENGDU KEER PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHENGDU KEER PHARMACEUTICAL CO Ltd filed Critical CHENGDU KEER PHARMACEUTICAL CO Ltd
Publication of GB201306569D0 publication Critical patent/GB201306569D0/en
Publication of GB2497899A publication Critical patent/GB2497899A/en
Application granted granted Critical
Publication of GB2497899B publication Critical patent/GB2497899B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739—Sanguisorba (burnet)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
GB1306569.3A 2010-09-14 2011-09-14 Sanguiin for use in the prevention or treatment of bone marrow inhibition Active GB2497899B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201010280772 2010-09-14
CN201110186932 2011-07-05
PCT/CN2011/079633 WO2012034519A1 (en) 2010-09-14 2011-09-14 Tannin extract of sanguisorba officinalis l. and preparation method and use thereof

Publications (3)

Publication Number Publication Date
GB201306569D0 GB201306569D0 (en) 2013-05-22
GB2497899A GB2497899A (en) 2013-06-26
GB2497899B true GB2497899B (en) 2018-05-30

Family

ID=45831012

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1306569.3A Active GB2497899B (en) 2010-09-14 2011-09-14 Sanguiin for use in the prevention or treatment of bone marrow inhibition

Country Status (5)

Country Link
CN (3) CN103784434A (en)
GB (1) GB2497899B (en)
MY (1) MY173437A (en)
SG (2) SG10201505752QA (en)
WO (1) WO2012034519A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103223036A (en) * 2013-04-16 2013-07-31 阚兆云 Traditional Chinese medicinal composition
CN104435220B (en) * 2013-09-22 2018-01-05 成都百草和济科技有限公司 Treat the combination medicine of bone marrow suppression
CN104623015A (en) * 2013-11-08 2015-05-20 成都百草和济科技有限公司 New application of garden burnet root and India madder root composition
GB201413228D0 (en) 2014-07-25 2014-09-10 Nugerontix Ltd Polyphenol compositions
CN105147804B (en) * 2015-08-28 2019-04-09 四川英路维特医药科技有限公司 A kind of radix sanguisorbae total saponin extract and its preparation method and application
US10155069B2 (en) 2016-09-09 2018-12-18 King Abdulaziz University Bone graft with a tannin-hydroxyapatite scaffold and stem cells for bone engineering
CN112876523B (en) * 2021-03-30 2023-07-25 江西海富生物工程有限公司 Method for recovering tannic acid from fructus momordicae, sweet tea or stevia rebaudiana floc residues
CN114577970B (en) * 2022-02-18 2023-05-12 江西普正制药股份有限公司 Method for establishing blood level tablet fingerprint and fingerprint thereof
CN115232516B (en) * 2022-06-27 2023-06-06 中南林业科技大学 Anti-adhesion coating with camellia saponin as main component, preparation method thereof and application thereof in inhibiting bacillus cereus
CN115998703A (en) * 2022-12-14 2023-04-25 迪沙药业集团有限公司 Sanguisorba composition and preparation method thereof
CN116688012B (en) * 2023-07-05 2024-06-04 浙江工业大学 Buccal tablet for preventing influenza

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58103383A (en) * 1981-12-12 1983-06-20 Nippon Shinyaku Co Ltd New tannin
JPS58154571A (en) * 1982-03-08 1983-09-14 Nippon Shinyaku Co Ltd Novel tannin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1824631A (en) * 2005-12-29 2006-08-30 谢君 Molecular modification method of active fat soluble plant polyphenol kind substance
JP5528025B2 (en) * 2008-08-22 2014-06-25 花王株式会社 TG synthesis inhibitor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58103383A (en) * 1981-12-12 1983-06-20 Nippon Shinyaku Co Ltd New tannin
JPS58154571A (en) * 1982-03-08 1983-09-14 Nippon Shinyaku Co Ltd Novel tannin

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
DING Huihuang, Extraction, Seperation and in vitro Antioxidative Effects of Proanthocyanidins in Radix Sanguisorbae, CHINESE MASTER'S THESES FULL-TEXT DATABASE, MEDICINE AND HEALTH SCIENCES, 15 June 2009, No. 6, pages E057-18 *
DING Weibin, et al., Pharmacological Research of Procyanidins Dimmers, WEST CHINA JOUNRAL OF PHARMACEUTICAL SCIENCES, Oct. 2008, Vol. 23, No. 5, pages 582-585 *
GONG Chenrui, et al., Study on Protective Action of Proanthocyanidins on Radiation Damage, FOOD SCIENCE, June 2008, Vol. 29, No. 6, pages 412-414 *
JIANG Guiquan, et al., Extraction of Oligoprocyanidins from the Root of Sanguisorba officinalis L., JOURNAL OF NORTHEAST FORESTRY UNIVERSITY, January 2008, Vol. 36, No. 1, pages 41-42 *
Journal of chemical ecology, vol 8, no 10, 1982, Temple, Alice S., "Tannin-measuring techniques: A review", p1289-1298 *
LI Hongsheng, et al., Clinical Study on Diyushengbai Tablet to Prevent Myleosuppression of Patients with Breast Cancer by Neoadjuvant Chemotherapy, CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY, April 2005, Vol. 12, No. 4, pages 397-398 *
LIU Jing, et al., A Study of the Protective Effect of Proanthocyanidins Sustained-release Tablets on Radiation Injured Mice, PHARMACEUTICAL JOURNAL OF CHINESE PEOPLE'S LIBERATION ARMY, 20 Oct. 2010, Vol. 26, No. 5, pages 406-408 *
MA Qiang, Report of 90 cases of Diyushengbai Tablet on Preventing Bone Marrow Depression Induced by Radiotherapy or Chemotherapy, SHANDONG MEDICAL JOURNAL, April 2005, Vol. 45, No. 4, pages 37 *
WANG Manli, et al., Extraction of Tannin and Saponin from Sangujsorba, JOURNAL OF GUIZHOU INSTITUTE OF TECHNOLOGY, June 1993, Vol. 22, No. 2, pages 105-108,63 *
ZENG Zhayou, et al., Therapeutic Effect of Diyushengbai Tablet on Preventing Leucopenia Caused by Included Paclitaxel Chemotherapy, MEDICAL JOURNAL OF WEST CHINA, July 2007, Vol. 19, No. 4, pages 590-591, 593 *
ZHOU Benhong, et al., Separation and Purification of Tannins from Sanguisorba by Macroporous Adsorbent Resin, CHINA PHARMACIST, May 2011, Vol. 14, No. 5, pages 685-688 *

Also Published As

Publication number Publication date
GB2497899A (en) 2013-06-26
CN103784434A (en) 2014-05-14
CN103079560A (en) 2013-05-01
SG188529A1 (en) 2013-04-30
SG10201505752QA (en) 2015-09-29
MY173437A (en) 2020-01-24
GB201306569D0 (en) 2013-05-22
CN103948710A (en) 2014-07-30
WO2012034519A1 (en) 2012-03-22

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