GB2436745B - Method for enhancing the solubility of paclitaxel - Google Patents

Method for enhancing the solubility of paclitaxel

Info

Publication number
GB2436745B
GB2436745B GB0707402A GB0707402A GB2436745B GB 2436745 B GB2436745 B GB 2436745B GB 0707402 A GB0707402 A GB 0707402A GB 0707402 A GB0707402 A GB 0707402A GB 2436745 B GB2436745 B GB 2436745B
Authority
GB
United Kingdom
Prior art keywords
paclitaxel
solubility
enhancing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0707402A
Other versions
GB2436745B8 (en
GB2436745A8 (en
GB0707402D0 (en
GB2436745A (en
Inventor
Young-Il Jeong
Jae-Woon Nah
Teok Rae Jung
Mi Kyeong Jang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB0707402D0 publication Critical patent/GB0707402D0/en
Publication of GB2436745A publication Critical patent/GB2436745A/en
Application granted granted Critical
Publication of GB2436745B publication Critical patent/GB2436745B/en
Publication of GB2436745B8 publication Critical patent/GB2436745B8/en
Publication of GB2436745A8 publication Critical patent/GB2436745A8/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
GB0707402.4A 2005-09-09 2005-09-09 Method for enhancing the solubility of paclitaxel Active GB2436745B8 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2005/002988 WO2007029898A1 (en) 2005-09-09 2005-09-09 Water soluble chitosan nanoparticle for delivering an anticancer agent and preparing method thereof

Publications (5)

Publication Number Publication Date
GB0707402D0 GB0707402D0 (en) 2007-05-23
GB2436745A GB2436745A (en) 2007-10-03
GB2436745B true GB2436745B (en) 2011-03-16
GB2436745B8 GB2436745B8 (en) 2019-03-13
GB2436745A8 GB2436745A8 (en) 2019-03-13

Family

ID=37835997

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0707402.4A Active GB2436745B8 (en) 2005-09-09 2005-09-09 Method for enhancing the solubility of paclitaxel

Country Status (4)

Country Link
JP (1) JP5116108B2 (en)
CN (1) CN101273066B (en)
GB (1) GB2436745B8 (en)
WO (1) WO2007029898A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL221351B1 (en) * 2012-03-14 2016-03-31 Politechnika Warszawska Method for obtaining polysaccharide nanoparticles
WO2013172999A1 (en) * 2012-05-16 2013-11-21 Mewa Singh Pharmaceutical compositions for the delivery of substantially water-insoluble drugs
KR101457478B1 (en) * 2013-04-10 2014-11-06 순천대학교 산학협력단 Composition for anti-green algae containing water soluble free amine chitosan and method removing green algaes using the same
CN106822906B (en) * 2016-12-30 2020-08-04 四川大学 Water-dispersible acid-responsive lymph-targeting slow-release carrier nano-carbon, preparation method and application

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN191203B (en) * 1999-02-17 2003-10-04 Amarnath Prof Maitra

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Biomaterials Vol. 23, No. 13, 2002, Nsereko et al, "Localized delivery of paclitaxel in solid tumors from biodegradable chitin microparticle formulations", pages 2723-2731. *
Bull. Korean Chem. Soc. Vol. 24, No. 9, 2003, Jang et al, "Characterization and modification of low molecular water-soluble chitosan for pharmaceutical application", pages 1303-1307. *
Eur. J. Pharm. Biopham. Vol. 57, 2004, Reul-Cariepy et al, "A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel", pages 56-63. *

Also Published As

Publication number Publication date
GB2436745B8 (en) 2019-03-13
GB2436745A8 (en) 2019-03-13
JP5116108B2 (en) 2013-01-09
GB0707402D0 (en) 2007-05-23
WO2007029898A1 (en) 2007-03-15
CN101273066B (en) 2013-10-16
CN101273066A (en) 2008-09-24
JP2009507825A (en) 2009-02-26
GB2436745A (en) 2007-10-03

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S117 Correction of errors in patents and applications (sect. 117/patents act 1977)

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S117 Correction of errors in patents and applications (sect. 117/patents act 1977)

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732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20190509 AND 20190515