GB2427470A - Detection of nucleic acids - Google Patents

Detection of nucleic acids

Info

Publication number
GB2427470A
GB2427470A GB0616288A GB0616288A GB2427470A GB 2427470 A GB2427470 A GB 2427470A GB 0616288 A GB0616288 A GB 0616288A GB 0616288 A GB0616288 A GB 0616288A GB 2427470 A GB2427470 A GB 2427470A
Authority
GB
United Kingdom
Prior art keywords
detection
nucleic acids
nucleic acid
resistivity
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0616288A
Other versions
GB0616288D0 (en
Inventor
Seamus Patrick John Higson
Frank Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cranfield University
Original Assignee
Cranfield University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cranfield University filed Critical Cranfield University
Publication of GB0616288D0 publication Critical patent/GB0616288D0/en
Publication of GB2427470A publication Critical patent/GB2427470A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A single stranded nucleic acid is deposited on an electrode whose resistivity or impedance is monitored. When the electrode is placed in a solution containing complementary nucleic acid, its resistivity and impedance change.
GB0616288A 2004-02-25 2005-02-25 Detection of nucleic acids Withdrawn GB2427470A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0404135.6A GB0404135D0 (en) 2004-02-25 2004-02-25 Impedimetric DNA hybridisation sensor
PCT/GB2005/000709 WO2005083116A2 (en) 2004-02-25 2005-02-25 Detection of nucleic acids

Publications (2)

Publication Number Publication Date
GB0616288D0 GB0616288D0 (en) 2006-09-27
GB2427470A true GB2427470A (en) 2006-12-27

Family

ID=32050812

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0404135.6A Ceased GB0404135D0 (en) 2004-02-25 2004-02-25 Impedimetric DNA hybridisation sensor
GB0616288A Withdrawn GB2427470A (en) 2004-02-25 2005-02-25 Detection of nucleic acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB0404135.6A Ceased GB0404135D0 (en) 2004-02-25 2004-02-25 Impedimetric DNA hybridisation sensor

Country Status (2)

Country Link
GB (2) GB0404135D0 (en)
WO (1) WO2005083116A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096825A (en) * 1994-04-22 2000-08-01 Bio Merieux Electrically conductive electroactive functionalized conjugated polymers, and uses thereof
US6468785B1 (en) * 1999-02-19 2002-10-22 New Mexico State University Technology Transfer Corporation Doped conducting polymers applications and methods
DE10214719A1 (en) * 2002-04-03 2003-11-20 Infineon Technologies Ag Sensor for the qualitative and quantitative determination of (bio) organic oligomers and polymers, analysis methods for this as well as methods for producing the sensor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096825A (en) * 1994-04-22 2000-08-01 Bio Merieux Electrically conductive electroactive functionalized conjugated polymers, and uses thereof
US6468785B1 (en) * 1999-02-19 2002-10-22 New Mexico State University Technology Transfer Corporation Doped conducting polymers applications and methods
DE10214719A1 (en) * 2002-04-03 2003-11-20 Infineon Technologies Ag Sensor for the qualitative and quantitative determination of (bio) organic oligomers and polymers, analysis methods for this as well as methods for producing the sensor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Electrochemistry Communications (2002), Vol 4, pp 773-779, "DNA-templated assembly and...", Yong et al *

Also Published As

Publication number Publication date
WO2005083116A2 (en) 2005-09-09
GB0616288D0 (en) 2006-09-27
GB0404135D0 (en) 2004-03-31
WO2005083116A3 (en) 2006-02-23

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)