GB2402128A - Spherical calcium phosphate molding and use thereof - Google Patents

Spherical calcium phosphate molding and use thereof Download PDF

Info

Publication number
GB2402128A
GB2402128A GB0421658A GB0421658A GB2402128A GB 2402128 A GB2402128 A GB 2402128A GB 0421658 A GB0421658 A GB 0421658A GB 0421658 A GB0421658 A GB 0421658A GB 2402128 A GB2402128 A GB 2402128A
Authority
GB
United Kingdom
Prior art keywords
beads
molding
calcium phosphate
holes
aggregate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0421658A
Other versions
GB0421658D0 (en
GB2402128B (en
Inventor
Kay Teraoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Original Assignee
National Institute of Advanced Industrial Science and Technology AIST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institute of Advanced Industrial Science and Technology AIST filed Critical National Institute of Advanced Industrial Science and Technology AIST
Publication of GB0421658D0 publication Critical patent/GB0421658D0/en
Publication of GB2402128A publication Critical patent/GB2402128A/en
Application granted granted Critical
Publication of GB2402128B publication Critical patent/GB2402128B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/322—Preparation by neutralisation of orthophosphoric acid
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/447—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on phosphates, e.g. hydroxyapatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
    • C04B38/0003—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof containing continuous channels, e.g. of the "dead-end" type or obtained by pushing bars in the green ceramic product
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
    • C04B38/0051—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof characterised by the pore size, pore shape or kind of porosity
    • C04B38/0058—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof characterised by the pore size, pore shape or kind of porosity open porosity
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/02—Composition of constituents of the starting material or of secondary phases of the final product
    • C04B2235/30—Constituents and secondary phases not being of a fibrous nature
    • C04B2235/32—Metal oxides, mixed metal oxides, or oxide-forming salts thereof, e.g. carbonates, nitrates, (oxy)hydroxides, chlorides
    • C04B2235/3205—Alkaline earth oxides or oxide forming salts thereof, e.g. beryllium oxide
    • C04B2235/3208—Calcium oxide or oxide-forming salts thereof, e.g. lime
    • C04B2235/3212—Calcium phosphates, e.g. hydroxyapatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/70—Aspects relating to sintered or melt-casted ceramic products
    • C04B2235/94—Products characterised by their shape

Abstract

Calcium phosphate ceramic beads having through-holes, an aggregate of the beads, new usage forms thereof, etc. In particular, calcium phosphate ceramic molding capable of forming a porous body with completely or partially communicating holes when charged in a given space so as to construct an aggregate, especially, calcium phosphate ceramic beads characterized in that (1) the molding has one or more through-holes, (2) the molding is an aggregate or a sintered body, and (3) the molding is in the form of beads. There are provided a productive process thereof, a beads aggregate composed of the above beads as a minimum constituent unit a beads accumulation wherein beads are accumulated in such a manner that the through-holes thereof are oriented in a given direction, and various carriers utilizing the functions of such a porous body with completely or partially communicating holes.

Description

GB 2402128 A continuation (72) Inventor(s): Kay Teraoka (74) Agent and/or
Address for Service: Langner Parry High Holborn House, 52-54 High Holborn, LONDON, WC1V ERR, United Kingdom
GB0421658A 2002-03-12 2003-03-12 Porous body of calcium phosphate beads and method of manufacture Expired - Fee Related GB2402128B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2002066375 2002-03-12
JP2002176600 2002-06-18
JP2002176615 2002-06-18
PCT/JP2003/002922 WO2003075973A1 (en) 2002-03-12 2003-03-12 Spherical calcium phosphate molding and use thereof

Publications (3)

Publication Number Publication Date
GB0421658D0 GB0421658D0 (en) 2004-10-27
GB2402128A true GB2402128A (en) 2004-12-01
GB2402128B GB2402128B (en) 2006-10-04

Family

ID=27808411

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0421658A Expired - Fee Related GB2402128B (en) 2002-03-12 2003-03-12 Porous body of calcium phosphate beads and method of manufacture

Country Status (3)

Country Link
AU (1) AU2003221357A1 (en)
GB (1) GB2402128B (en)
WO (1) WO2003075973A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017098025A1 (en) * 2015-12-11 2017-06-15 Forschungsinstitut Für Anorganische Werkstoffe - Glas Keramik Gmbh Method and apparatus for producing microspheres containing a sinterable substance

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2422844A (en) * 2003-11-19 2006-08-09 Nat Inst Of Advanced Ind Scien Cell picking tool including molding with cell-adhesive recessed structure and method of cell manipulation
JP4599588B2 (en) * 2003-11-19 2010-12-15 独立行政法人産業技術総合研究所 Cell manipulation method using cell picking tool comprising molded article with cell adhesive concave structure
WO2006090777A1 (en) * 2005-02-23 2006-08-31 Hi-Lex Corporation Medical material, artificial tooth root and method of producing material for clinical use
JP2006263445A (en) * 2005-02-25 2006-10-05 Yasuharu Noisshiki Medical material
JP5166864B2 (en) * 2005-02-23 2013-03-21 株式会社ハイレックスコーポレーション Artificial tooth root
EP2457538A4 (en) * 2009-07-22 2015-03-25 Next21 Kk Artificial bone constructing unit and artificial bone constructing system
CN101904775B (en) * 2010-06-25 2013-07-24 西安交通大学 Tissue-like manufacture die based on spheroid elementary unit and preparation process
CN105380732B (en) * 2015-12-14 2017-05-31 宋占涛 Bone renovating material with more-dimensional channels structure

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007495A1 (en) * 1986-06-09 1987-12-17 Coors Biomedical Company Biocompatible particles and cloth-like article made therefrom
US4960426A (en) * 1987-08-26 1990-10-02 Denatal Kagaku Kabushiki Kaisha Osteofillers of hydroxy apatite
JPH03294221A (en) * 1990-04-10 1991-12-25 Ngk Spark Plug Co Ltd Ceramic material containing persistent drug
JPH0447422U (en) * 1990-08-27 1992-04-22
JPH08336584A (en) * 1995-06-12 1996-12-24 Natl Inst For Res In Inorg Mater Porous apatite body for artificial marrow

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007495A1 (en) * 1986-06-09 1987-12-17 Coors Biomedical Company Biocompatible particles and cloth-like article made therefrom
US4960426A (en) * 1987-08-26 1990-10-02 Denatal Kagaku Kabushiki Kaisha Osteofillers of hydroxy apatite
JPH03294221A (en) * 1990-04-10 1991-12-25 Ngk Spark Plug Co Ltd Ceramic material containing persistent drug
JPH0447422U (en) * 1990-08-27 1992-04-22
JPH08336584A (en) * 1995-06-12 1996-12-24 Natl Inst For Res In Inorg Mater Porous apatite body for artificial marrow

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017098025A1 (en) * 2015-12-11 2017-06-15 Forschungsinstitut Für Anorganische Werkstoffe - Glas Keramik Gmbh Method and apparatus for producing microspheres containing a sinterable substance

Also Published As

Publication number Publication date
GB0421658D0 (en) 2004-10-27
WO2003075973A1 (en) 2003-09-18
GB2402128B (en) 2006-10-04
AU2003221357A1 (en) 2003-09-22

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20131114 AND 20131120

PCNP Patent ceased through non-payment of renewal fee

Effective date: 20140312