GB240051A - The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives - Google Patents
The manufacture of quinoline-4-aldehyde and its 2-position aryl derivativesInfo
- Publication number
- GB240051A GB240051A GB108025A GB108025A GB240051A GB 240051 A GB240051 A GB 240051A GB 108025 A GB108025 A GB 108025A GB 108025 A GB108025 A GB 108025A GB 240051 A GB240051 A GB 240051A
- Authority
- GB
- United Kingdom
- Prior art keywords
- quinoline
- aldehyde
- acrylic acid
- phenylquinoline
- aryl derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Quinoline-4-aldehyde and its 2-aryl derivatives are obtained by oxidation of the corresponding 4-acrylic acid in alkali solution in the presence of a solvent not miscible with water. The products possess therapeutic properties. Examples are given of the production of quinoline-4-aldehyde and of 2-phenylquinoline-4-aldehyde by treatment of quinoline-4-acrylic acid and 2-phenylquinoline-4-acrylic acid respectively in sodium carbonate solution with potassium permanganate, the ice-cooled mixture being covered with a layer of benzene. 2-Phenylquinoline-4-acrylic acid is prepared by saponifying the product obtained by heating 2-phenyl-4-methylquinoline with chloral.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB108025A GB240051A (en) | 1925-01-13 | 1925-01-13 | The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB108025A GB240051A (en) | 1925-01-13 | 1925-01-13 | The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB240051A true GB240051A (en) | 1925-09-24 |
Family
ID=9715813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB108025A Expired GB240051A (en) | 1925-01-13 | 1925-01-13 | The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB240051A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2858619A1 (en) * | 2003-08-08 | 2005-02-11 | Aventis Pharma Sa | New 4-substituted quinoline derivatives are useful to treat bacterial infections in humans |
US7348434B2 (en) | 2003-08-08 | 2008-03-25 | Antony Bigot | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
-
1925
- 1925-01-13 GB GB108025A patent/GB240051A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2858619A1 (en) * | 2003-08-08 | 2005-02-11 | Aventis Pharma Sa | New 4-substituted quinoline derivatives are useful to treat bacterial infections in humans |
US7348434B2 (en) | 2003-08-08 | 2008-03-25 | Antony Bigot | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
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