GB240051A - The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives - Google Patents

The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives

Info

Publication number
GB240051A
GB240051A GB108025A GB108025A GB240051A GB 240051 A GB240051 A GB 240051A GB 108025 A GB108025 A GB 108025A GB 108025 A GB108025 A GB 108025A GB 240051 A GB240051 A GB 240051A
Authority
GB
United Kingdom
Prior art keywords
quinoline
aldehyde
acrylic acid
phenylquinoline
aryl derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB108025A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHEM FAB AUF ACTIEN
Original Assignee
CHEM FAB AUF ACTIEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHEM FAB AUF ACTIEN filed Critical CHEM FAB AUF ACTIEN
Priority to GB108025A priority Critical patent/GB240051A/en
Publication of GB240051A publication Critical patent/GB240051A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Quinoline-4-aldehyde and its 2-aryl derivatives are obtained by oxidation of the corresponding 4-acrylic acid in alkali solution in the presence of a solvent not miscible with water. The products possess therapeutic properties. Examples are given of the production of quinoline-4-aldehyde and of 2-phenylquinoline-4-aldehyde by treatment of quinoline-4-acrylic acid and 2-phenylquinoline-4-acrylic acid respectively in sodium carbonate solution with potassium permanganate, the ice-cooled mixture being covered with a layer of benzene. 2-Phenylquinoline-4-acrylic acid is prepared by saponifying the product obtained by heating 2-phenyl-4-methylquinoline with chloral.
GB108025A 1925-01-13 1925-01-13 The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives Expired GB240051A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB108025A GB240051A (en) 1925-01-13 1925-01-13 The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB108025A GB240051A (en) 1925-01-13 1925-01-13 The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives

Publications (1)

Publication Number Publication Date
GB240051A true GB240051A (en) 1925-09-24

Family

ID=9715813

Family Applications (1)

Application Number Title Priority Date Filing Date
GB108025A Expired GB240051A (en) 1925-01-13 1925-01-13 The manufacture of quinoline-4-aldehyde and its 2-position aryl derivatives

Country Status (1)

Country Link
GB (1) GB240051A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858619A1 (en) * 2003-08-08 2005-02-11 Aventis Pharma Sa New 4-substituted quinoline derivatives are useful to treat bacterial infections in humans
US7348434B2 (en) 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858619A1 (en) * 2003-08-08 2005-02-11 Aventis Pharma Sa New 4-substituted quinoline derivatives are useful to treat bacterial infections in humans
US7348434B2 (en) 2003-08-08 2008-03-25 Antony Bigot 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them

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