GB2371548B - Sequences encoding NADH oxidase/protein disulphide-thiol interchange polypeptides and their use in diagnosing neoplasia - Google Patents

Sequences encoding NADH oxidase/protein disulphide-thiol interchange polypeptides and their use in diagnosing neoplasia

Info

Publication number
GB2371548B
GB2371548B GB0210912A GB0210912A GB2371548B GB 2371548 B GB2371548 B GB 2371548B GB 0210912 A GB0210912 A GB 0210912A GB 0210912 A GB0210912 A GB 0210912A GB 2371548 B GB2371548 B GB 2371548B
Authority
GB
United Kingdom
Prior art keywords
polypeptides
sequences encoding
nadh oxidase
protein disulphide
encoding nadh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0210912A
Other versions
GB2371548A (en
GB0210912D0 (en
Inventor
D James Morre
Dorothy M Morre
Pin-Ju Chueh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of GB0210912D0 publication Critical patent/GB0210912D0/en
Publication of GB2371548A publication Critical patent/GB2371548A/en
Application granted granted Critical
Publication of GB2371548B publication Critical patent/GB2371548B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GB0210912A 1999-11-01 2000-11-01 Sequences encoding NADH oxidase/protein disulphide-thiol interchange polypeptides and their use in diagnosing neoplasia Expired - Fee Related GB2371548B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16264499P 1999-11-01 1999-11-01
PCT/US2000/030190 WO2001032673A1 (en) 1999-11-01 2000-11-01 Sequences encoding human neoplastic marker

Publications (3)

Publication Number Publication Date
GB0210912D0 GB0210912D0 (en) 2002-06-19
GB2371548A GB2371548A (en) 2002-07-31
GB2371548B true GB2371548B (en) 2004-11-24

Family

ID=22586517

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0210912A Expired - Fee Related GB2371548B (en) 1999-11-01 2000-11-01 Sequences encoding NADH oxidase/protein disulphide-thiol interchange polypeptides and their use in diagnosing neoplasia

Country Status (5)

Country Link
JP (1) JP2003517299A (en)
AU (1) AU1453701A (en)
CA (1) CA2388612A1 (en)
GB (1) GB2371548B (en)
WO (1) WO2001032673A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
US20060292577A1 (en) * 2005-06-27 2006-12-28 Purdue Research Foundation Neoplasia-specific splice variants and methods
GB2441860B (en) * 2006-09-01 2011-06-29 Nox Technologies Inc Detecting Neoplasia-specific tNOX isoforms
US9612243B1 (en) * 2016-05-31 2017-04-04 Mor-Nuco Enterprises, Inc. Methods and compositions for targeted two-dimensional western blot analysis for early cancer detection and cancer diagnosis up to ten years in advance of clinical symptoms of malignant disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605810A (en) * 1994-04-05 1997-02-25 Purdue Research Foundation NADH oxidase assay for neoplasia determination
WO1999004265A2 (en) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Cancer associated nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605810A (en) * 1994-04-05 1997-02-25 Purdue Research Foundation NADH oxidase assay for neoplasia determination
WO1999004265A2 (en) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Cancer associated nucleic acids and polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GENBANK Accession No. AF207881. Chueh et al. (29 December 1999) *
GENBANK Accession No. Q9UH82. Chueh et al. (01 May 2000) *
GENBANK Accession No. X39889. Chen et al (28 January 1999) *

Also Published As

Publication number Publication date
CA2388612A1 (en) 2001-05-10
AU1453701A (en) 2001-05-14
JP2003517299A (en) 2003-05-27
WO2001032673A9 (en) 2002-07-04
WO2001032673A1 (en) 2001-05-10
GB2371548A (en) 2002-07-31
GB0210912D0 (en) 2002-06-19

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20081101