GB2306961B - Cathepsin L at high specific actvity and recombinant manufacture thereof - Google Patents

Cathepsin L at high specific actvity and recombinant manufacture thereof

Info

Publication number
GB2306961B
GB2306961B GB9622436A GB9622436A GB2306961B GB 2306961 B GB2306961 B GB 2306961B GB 9622436 A GB9622436 A GB 9622436A GB 9622436 A GB9622436 A GB 9622436A GB 2306961 B GB2306961 B GB 2306961B
Authority
GB
United Kingdom
Prior art keywords
actvity
cathepsin
high specific
recombinant manufacture
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9622436A
Other versions
GB9622436D0 (en
GB2306961A (en
Inventor
Robert Douglas Gordon
Giles Anthony Hassall
Bhupendra Vallabh Kara
Richard Alexander Pauptit
David Pioli
Alexander Dunbar Tucker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9522660.1A external-priority patent/GB9522660D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Priority to GB9622436A priority Critical patent/GB2306961B/en
Publication of GB9622436D0 publication Critical patent/GB9622436D0/en
Publication of GB2306961A publication Critical patent/GB2306961A/en
Application granted granted Critical
Publication of GB2306961B publication Critical patent/GB2306961B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
GB9622436A 1995-11-04 1996-10-29 Cathepsin L at high specific actvity and recombinant manufacture thereof Expired - Fee Related GB2306961B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9622436A GB2306961B (en) 1995-11-04 1996-10-29 Cathepsin L at high specific actvity and recombinant manufacture thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9522660.1A GB9522660D0 (en) 1995-11-04 1995-11-04 Protein
GB9622436A GB2306961B (en) 1995-11-04 1996-10-29 Cathepsin L at high specific actvity and recombinant manufacture thereof

Publications (3)

Publication Number Publication Date
GB9622436D0 GB9622436D0 (en) 1997-01-08
GB2306961A GB2306961A (en) 1997-05-14
GB2306961B true GB2306961B (en) 1998-06-10

Family

ID=26308058

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9622436A Expired - Fee Related GB2306961B (en) 1995-11-04 1996-10-29 Cathepsin L at high specific actvity and recombinant manufacture thereof

Country Status (1)

Country Link
GB (1) GB2306961B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834228A (en) * 1997-02-13 1998-11-10 Merck & Co., Inc. Method for identifying inhibitors for apopain based upon the crystal structure of the apopain: Ac-DEVD-CHO complex
FR2767833B1 (en) 1997-08-29 2001-03-02 Oreal ISOLATED SKIN POLYPEPTIDE AND ITS USE
US6842704B2 (en) 1998-02-04 2005-01-11 Immunex Corporation Crystalline TNF-α-converting enzyme and uses thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Biol. Chem. Hoppe-Seyler, Vol. 376, June 1995, pages 385 to 388 *
Biosci. Biotech. Biochem., Vol. 57, No. 9, 1993, pages 1470 to 1476 *
Comp. Biochem. Physiol., Vol 96B, No. 2, 1990, pages 247 to 252 *
Febs letters, Vol. 336, No. 3, 1993, pages 555 to 559 *
J. Biochem., Vol. 87, No. 4, 1980, pages 1133 to 1143 *
Journal of Chromatography, Vol. 568, No. 1, 1991, pages 55 to 68 *

Also Published As

Publication number Publication date
GB9622436D0 (en) 1997-01-08
GB2306961A (en) 1997-05-14

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20121029