AU3479495A - Alpha-1-antitrypsin and antithrombine-iii variants - Google Patents

Alpha-1-antitrypsin and antithrombine-iii variants

Info

Publication number
AU3479495A
AU3479495A AU34794/95A AU3479495A AU3479495A AU 3479495 A AU3479495 A AU 3479495A AU 34794/95 A AU34794/95 A AU 34794/95A AU 3479495 A AU3479495 A AU 3479495A AU 3479495 A AU3479495 A AU 3479495A
Authority
AU
Australia
Prior art keywords
antithrombine
antitrypsin
alpha
iii variants
variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34794/95A
Inventor
Robin Carrell
Damian Crowther
Paul C. R Hopkins
Stuart Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PPL Therapeutics Scotland Ltd
Original Assignee
PPL Therapeutics Scotland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9419804A external-priority patent/GB9419804D0/en
Priority claimed from GBGB9502138.2A external-priority patent/GB9502138D0/en
Application filed by PPL Therapeutics Scotland Ltd filed Critical PPL Therapeutics Scotland Ltd
Publication of AU3479495A publication Critical patent/AU3479495A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU34794/95A 1994-09-30 1995-09-12 Alpha-1-antitrypsin and antithrombine-iii variants Abandoned AU3479495A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9419804A GB9419804D0 (en) 1994-09-30 1994-09-30 Proteins
GB9419804 1994-09-30
GB9502138 1995-02-03
GBGB9502138.2A GB9502138D0 (en) 1995-02-03 1995-02-03 Proteins
PCT/GB1995/002155 WO1996010638A1 (en) 1994-09-30 1995-09-12 Alpha-1-antitrypsin and antithrombine-iii variants

Publications (1)

Publication Number Publication Date
AU3479495A true AU3479495A (en) 1996-04-26

Family

ID=26305719

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34794/95A Abandoned AU3479495A (en) 1994-09-30 1995-09-12 Alpha-1-antitrypsin and antithrombine-iii variants

Country Status (3)

Country Link
AU (1) AU3479495A (en)
IL (1) IL115317A0 (en)
WO (1) WO1996010638A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19903693A1 (en) * 1998-04-24 1999-10-28 Centeon Pharma Gmbh Protease for activation of coagulation factor VII
GB2318732A (en) 1996-11-01 1998-05-06 Johnson & Johnson Medical Wound healing compositions containing alpha-1-antitrypsin
ES2299425T3 (en) * 1999-05-13 2008-06-01 Gtc Biotherapeutics, Inc. ANTITROMBIN III GENETICALLY PRODUCED AND MUTING FORMS OF THE SAME.
US8563693B2 (en) 2001-01-26 2013-10-22 Acceleration Biopharmaceuticals, Inc. Method of treating human immunodeficiency virus infection in a mammal comprising administering heparin-activated antithrombin III
US20020127698A1 (en) 2001-01-26 2002-09-12 Ralf Geiben Lynn Serpin drugs for treatment of HIV infection and method of use thereof
GB0711779D0 (en) 2007-06-18 2007-07-25 Univ Singapore Thrombin inhibitor
ES2374054B1 (en) * 2010-07-03 2012-12-26 Instituto De Salud Carlos Iii NEW SERINA PROTEASA INHIBITOR AND ITS USE.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711848A (en) * 1984-03-14 1987-12-08 Zymogenetics, Inc. Site specific mutagenesis in alpha-1-antitrypsin
WO1986000337A1 (en) * 1984-06-19 1986-01-16 Transgene S.A. HUMAN alpha1-ANTITRYPSIN DERIVATIVES AND PREPARATION PROCESS THEREOF
EP0238473A3 (en) * 1986-03-18 1989-06-07 Monsanto Company Serine protease inhibitors
FR2599752B1 (en) * 1986-06-10 1989-11-03 Transgene Sa ALPHA1- ANTITRYPSIN VARIANTS USEFUL IN PARTICULAR AS KALLIKREIN INHIBITORS
IE902276A1 (en) * 1989-06-26 1991-01-16 Akzo Nv Serpin variants
JP3479539B2 (en) * 1992-04-10 2003-12-15 エーザイ株式会社 Human antithrombin III mutant

Also Published As

Publication number Publication date
WO1996010638A1 (en) 1996-04-11
IL115317A0 (en) 1995-12-31

Similar Documents

Publication Publication Date Title
AU3304795A (en) Bisresorcinyltriazines
AU2832295A (en) Cytoanalyzer
AU3304995A (en) 2-Hydroxyphenyltriazines
EP0690494A3 (en) Connection and build-up-process for multi-chip-modules
AU5040896A (en) Benzonitriles and benzofluorides
AU2837895A (en) Thiazine- or thiazepine-derivatives
AU4131596A (en) Polyglycomers
AU4044795A (en) Handleset
AU2523795A (en) Inhaler
AU1594495A (en) Diffuser
AU2308295A (en) Heterocyclylbenzonitriles
AU1963395A (en) Boom-structure
AU3634595A (en) Bis-oxazolidines and their use
AU3479495A (en) Alpha-1-antitrypsin and antithrombine-iii variants
AU4029295A (en) Thienopyridones
AU2512495A (en) Therapeutic phenoxyalkylazoles and phenoxyalkylazines
AU7469594A (en) Poop-scoop
AU5188296A (en) Carbopeptoids and carbonucleotoids
AU3166195A (en) Acylimidazopyridines
AU3429695A (en) Ventilator
AU4590996A (en) Boekomslag
AU3166095A (en) Benzylimidazopyridines
AU3776495A (en) Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas
AU2411395A (en) Hydrocopter
AU3446995A (en) Biodestumping