GB2306485B - Enzyme mutant - Google Patents

Enzyme mutant

Info

Publication number
GB2306485B
GB2306485B GB9622819A GB9622819A GB2306485B GB 2306485 B GB2306485 B GB 2306485B GB 9622819 A GB9622819 A GB 9622819A GB 9622819 A GB9622819 A GB 9622819A GB 2306485 B GB2306485 B GB 2306485B
Authority
GB
United Kingdom
Prior art keywords
enzyme mutant
mutant
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9622819A
Other versions
GB9622819D0 (en
GB2306485A (en
GB2306485A8 (en
Inventor
Luet-Lok Wong
Sabine Lahja Flitsch
Darren Paul Nickerson
Alwyn James Hart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
British Gas PLC
Original Assignee
British Gas PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9522407A external-priority patent/GB2294692B/en
Application filed by British Gas PLC filed Critical British Gas PLC
Publication of GB9622819D0 publication Critical patent/GB9622819D0/en
Publication of GB2306485A publication Critical patent/GB2306485A/en
Publication of GB2306485A8 publication Critical patent/GB2306485A8/en
Application granted granted Critical
Publication of GB2306485B publication Critical patent/GB2306485B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
GB9622819A 1995-11-01 1996-11-01 Enzyme mutant Expired - Fee Related GB2306485B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9522407A GB2294692B (en) 1994-11-03 1995-11-01 Enzyme mutant and method
PCT/GB1995/002588 WO1996014419A1 (en) 1994-11-03 1995-11-02 MUTANT MONO-OXYGENASE CYTOCHROME P-450¿cam?

Publications (4)

Publication Number Publication Date
GB9622819D0 GB9622819D0 (en) 1997-01-08
GB2306485A GB2306485A (en) 1997-05-07
GB2306485A8 GB2306485A8 (en) 1997-05-19
GB2306485B true GB2306485B (en) 1998-12-09

Family

ID=26306468

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9622819A Expired - Fee Related GB2306485B (en) 1995-11-01 1996-11-01 Enzyme mutant

Country Status (6)

Country Link
JP (1) JP2000508163A (en)
CN (1) CN1212015A (en)
CA (1) CA2236381A1 (en)
GB (1) GB2306485B (en)
SK (1) SK55598A3 (en)
WO (1) WO1997016553A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6902918B1 (en) * 1998-05-21 2005-06-07 California Institute Of Technology Oxygenase enzymes and screening method
GB9825421D0 (en) 1998-11-19 1999-01-13 Isis Innovation Process for oxidising terpenes
GB9914373D0 (en) 1999-06-18 1999-08-18 Isis Innovation Process for oxidising aromatic compounds
MY126592A (en) * 1999-07-27 2006-10-31 Basf Ag Novel cytochrome p450 monooxygenases and their use for the oxidation of organic compounds
US7465567B2 (en) 2001-04-16 2008-12-16 California Institute Of Technology Peroxide-driven cytochrome P450 oxygenase variants
US7226768B2 (en) 2001-07-20 2007-06-05 The California Institute Of Technology Cytochrome P450 oxygenases
WO2005017105A2 (en) 2003-06-17 2005-02-24 California University Of Technology Regio- and enantioselective alkane hydroxylation with modified cytochrome p450
DK1660646T3 (en) 2003-08-11 2015-03-09 California Inst Of Techn Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use
US11214817B2 (en) 2005-03-28 2022-01-04 California Institute Of Technology Alkane oxidation by modified hydroxylases
US8715988B2 (en) 2005-03-28 2014-05-06 California Institute Of Technology Alkane oxidation by modified hydroxylases
US7666220B2 (en) 2005-07-07 2010-02-23 Nellix, Inc. System and methods for endovascular aneurysm treatment
US8252559B2 (en) 2006-08-04 2012-08-28 The California Institute Of Technology Methods and systems for selective fluorination of organic molecules
WO2008016709A2 (en) 2006-08-04 2008-02-07 California Institute Of Technology Methods and systems for selective fluorination of organic molecules
GB0719620D0 (en) 2007-10-08 2007-11-14 Isis Innovation Mutant Enzymes
WO2013016207A2 (en) 2011-07-22 2013-01-31 California Institute Of Technology Stable fungal cel6 enzyme variants
CN108271374B (en) * 2015-07-07 2021-09-21 科德克希思公司 Novel P450-BM3 variants with improved activity

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2294692A (en) * 1994-11-03 1996-05-08 British Gas Plc Cytochrome P-450cam mutants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0733112B1 (en) * 1993-12-08 2007-01-10 Royal Veterinary & Agricultural University Cytochrome p-450 monooxygenases
GB2303853B (en) * 1994-06-16 1998-12-23 Us Health Variant alleles in cytochrome P450 expressing enzymes involved in metabolic processes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2294692A (en) * 1994-11-03 1996-05-08 British Gas Plc Cytochrome P-450cam mutants

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J.Amer.Chem.Soc. 1989,111,2715-2717 *
J.Biol.Chem. 1988,263(35),18842-18849 *
J.Biol.Chem. 1990,265(10),5361-5363 *

Also Published As

Publication number Publication date
CN1212015A (en) 1999-03-24
GB9622819D0 (en) 1997-01-08
SK55598A3 (en) 1999-04-13
JP2000508163A (en) 2000-07-04
WO1997016553A1 (en) 1997-05-09
CA2236381A1 (en) 1997-05-09
GB2306485A (en) 1997-05-07
GB2306485A8 (en) 1997-05-19

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Legal Events

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