GB2306485A8 - Mutants of mono-oxygenase cytochrome P-450cam - Google Patents

Mutants of mono-oxygenase cytochrome P-450cam

Info

Publication number
GB2306485A8
GB2306485A8 GB9622819A GB9622819A GB2306485A8 GB 2306485 A8 GB2306485 A8 GB 2306485A8 GB 9622819 A GB9622819 A GB 9622819A GB 9622819 A GB9622819 A GB 9622819A GB 2306485 A8 GB2306485 A8 GB 2306485A8
Authority
GB
United Kingdom
Prior art keywords
450cam
mutants
mono
oxygenase cytochrome
oxygenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9622819A
Other versions
GB2306485A (en
GB2306485B (en
GB9622819D0 (en
Inventor
Luet-Lok Wong
Sabine Lahja Flitsch
Darren Paul Nickerson
Alwyn James Hart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
British Gas PLC
Original Assignee
British Gas PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9522407A external-priority patent/GB2294692B/en
Application filed by British Gas PLC filed Critical British Gas PLC
Publication of GB9622819D0 publication Critical patent/GB9622819D0/en
Publication of GB2306485A publication Critical patent/GB2306485A/en
Publication of GB2306485A8 publication Critical patent/GB2306485A8/en
Application granted granted Critical
Publication of GB2306485B publication Critical patent/GB2306485B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB9622819A 1995-11-01 1996-11-01 Enzyme mutant Expired - Fee Related GB2306485B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9522407A GB2294692B (en) 1994-11-03 1995-11-01 Enzyme mutant and method
PCT/GB1995/002588 WO1996014419A1 (en) 1994-11-03 1995-11-02 MUTANT MONO-OXYGENASE CYTOCHROME P-450¿cam?

Publications (4)

Publication Number Publication Date
GB9622819D0 GB9622819D0 (en) 1997-01-08
GB2306485A GB2306485A (en) 1997-05-07
GB2306485A8 true GB2306485A8 (en) 1997-05-19
GB2306485B GB2306485B (en) 1998-12-09

Family

ID=26306468

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9622819A Expired - Fee Related GB2306485B (en) 1995-11-01 1996-11-01 Enzyme mutant

Country Status (6)

Country Link
JP (1) JP2000508163A (en)
CN (1) CN1212015A (en)
CA (1) CA2236381A1 (en)
GB (1) GB2306485B (en)
SK (1) SK55598A3 (en)
WO (1) WO1997016553A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6902918B1 (en) * 1998-05-21 2005-06-07 California Institute Of Technology Oxygenase enzymes and screening method
GB9825421D0 (en) 1998-11-19 1999-01-13 Isis Innovation Process for oxidising terpenes
GB9914373D0 (en) * 1999-06-18 1999-08-18 Isis Innovation Process for oxidising aromatic compounds
MY126592A (en) * 1999-07-27 2006-10-31 Basf Ag Novel cytochrome p450 monooxygenases and their use for the oxidation of organic compounds
EP1470219A4 (en) 2001-04-16 2005-10-05 California Inst Of Techn Peroxide-driven cytochrome p450 oxygenase variants
WO2003008563A2 (en) 2001-07-20 2003-01-30 California Institute Of Technology Improved cytochrome p450 oxygenases
EP1639091B1 (en) 2003-06-17 2012-12-05 California University Of Technology Regio- and enantioselective alkane hydroxylation with modified cytochrome p450
DK1660646T3 (en) 2003-08-11 2015-03-09 California Inst Of Techn Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use
US11214817B2 (en) 2005-03-28 2022-01-04 California Institute Of Technology Alkane oxidation by modified hydroxylases
US8715988B2 (en) 2005-03-28 2014-05-06 California Institute Of Technology Alkane oxidation by modified hydroxylases
AU2006269419A1 (en) 2005-07-07 2007-01-18 Nellix, Inc. Systems and methods for endovascular aneurysm treatment
US8252559B2 (en) 2006-08-04 2012-08-28 The California Institute Of Technology Methods and systems for selective fluorination of organic molecules
WO2008016709A2 (en) 2006-08-04 2008-02-07 California Institute Of Technology Methods and systems for selective fluorination of organic molecules
GB0719620D0 (en) 2007-10-08 2007-11-14 Isis Innovation Mutant Enzymes
WO2013016207A2 (en) 2011-07-22 2013-01-31 California Institute Of Technology Stable fungal cel6 enzyme variants
EP3319987B1 (en) * 2015-07-07 2021-05-05 Codexis, Inc. Novel p450-bm3 variants with improved activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0733112B1 (en) * 1993-12-08 2007-01-10 Royal Veterinary & Agricultural University Cytochrome p-450 monooxygenases
WO1995034679A2 (en) * 1994-06-16 1995-12-21 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Defects in drug metabolism
GB9422205D0 (en) * 1994-11-03 1994-12-21 British Gas Plc Enzyme mutant and method

Also Published As

Publication number Publication date
SK55598A3 (en) 1999-04-13
CA2236381A1 (en) 1997-05-09
CN1212015A (en) 1999-03-24
GB2306485A (en) 1997-05-07
GB2306485B (en) 1998-12-09
JP2000508163A (en) 2000-07-04
GB9622819D0 (en) 1997-01-08
WO1997016553A1 (en) 1997-05-09

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Legal Events

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