GB2306109A - A zinc containing composition for treating the common cold - Google Patents

A zinc containing composition for treating the common cold Download PDF

Info

Publication number
GB2306109A
GB2306109A GB9702528A GB9702528A GB2306109A GB 2306109 A GB2306109 A GB 2306109A GB 9702528 A GB9702528 A GB 9702528A GB 9702528 A GB9702528 A GB 9702528A GB 2306109 A GB2306109 A GB 2306109A
Authority
GB
United Kingdom
Prior art keywords
zinc
mgs
preventative
common cold
ascorbic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9702528A
Other versions
GB2306109A9 (en
GB2306109A8 (en
GB9702528D0 (en
GB2306109B (en
Inventor
John Wright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB9702528A priority Critical patent/GB2306109B/en
Publication of GB9702528D0 publication Critical patent/GB9702528D0/en
Publication of GB2306109A publication Critical patent/GB2306109A/en
Publication of GB2306109A9 publication Critical patent/GB2306109A9/en
Publication of GB2306109A8 publication Critical patent/GB2306109A8/en
Application granted granted Critical
Publication of GB2306109B publication Critical patent/GB2306109B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof

Abstract

The composition comprises amino acids, zinc, ascorbic acid (Vitamin C) and aspirin (acetylsalicylic acid). The amino acids, which are chelated by the zinc, promote zinc uptake across mucosal surfaces such as the gut. Vitamin C and aspirin are intended to promote intranasal uptake of the composition. The composition is in a dry powder form which may be incorporated into capsules or provided as a compressed tablet.

Description

RATIONALE FOR A COMMON COLD PROPHYLACTIC THERE APPEARS TO BE NO RESEARCH DATA AVAILABLE WHICH DIFFERENTIATES THE PHYSIOLOGICAL DIFFERENCE BETWEEN PERSONS WHO CATCH COLDS AND THOSE WHO DO NOT. AND YET THIS UNDERSTANDING WHICH NEEDS TO BE ESTABLISHED IS VITAL BECAUSE THE COMCLUSION TO BE DRAWN IS THAT THE PERSON WHO DOES NOT CATCH COLD @OSSESSES ANTI - VIRAL QUALITIES.
THE RHINOVIRUS, WHICH IS RESPONSIBLE, HAS AT LEAST 100 VARIANTS AND YET THAT PERSON RESISTS THEM ALL DES@ITE THEIR DIFFERENT@ CHARACTERISTICS. THE TAXONOMIC GROUPS OF VIRUSES ( FA@ILIES) NUMBER AT LEAST 18 AND THEY ARE ALSO DIVIDED IMTO SUB-FA@ILIES AND THOSE INTO VARIANTS.
ALL VIRUSES ARE DIFFERENT FROM EACH OTHER, IN SIZE, CONSTRUCTION, AND CONTENTS. IN ORDER TO EFFECT ENTRY INTO A POTENTIAL HOST CELL THEY EITHER INJECT OR INVADE.
HOWEVER, THE MODUS OPERANDI FOR ALL VIRUSES AT THE BEGINNING OF THE CYCLE OF INFECTION COMMENCES WITH THE SAME TWO STEPS. THE FIRST IS ASSIDENTAL- LANDING ON THE CELL. THE SECOND INVOLVES ATTACHING TO THE CELL SURFACE (ADSORBTION). AS VIRUSES ARE PARASITES THIS STEP IS VITAL IF THEY ARE TO PROCEED TO STEP THREE.
IT IS OBVIOUS FROM THIS THAT IF THOSE FIRST TWO STEPS CAN BE PREVENTED, THE VIRUS WILL BE MEUTRALISED. DENY THEM ACCESS TO THE NASAL MUCOSA AND THEY WILL REMAIN PASSIVE.
A PERSON WITH THIS ABILITY MUST BE DEEMED IMPERVIOUS TO VIRUSES A'1' THAT SIR OF INFECTION.
ESSENTIALY THE COMMON COLD IS A LOCAL AND SUPERFICIAL RESPONSE TO THE VIRUS, SOMEWHAT SIMILAR TO THAT CAUSED BY POLLEN AND PENETRATION TO THE BLOODSTREAM DOES NOT TAKE PLACE.
THEREFORE A T OR B CELL RESPONSE IS NOT INVOLVED.
ZINC IS NOT A NUTRIENT AS SUCH BUT IT IS VITAL IN THE STANDING FLUIDS OF THE BODY. IT IS PRESENT IN THE S@IN AND PERSPIRATION, IN THE PROSTATIC FLUIDS INCLUDING SEMEN, IN THE EYES AND BRAIN AND THE INTERNAL SURFACES SUCH AS THE MUCOUS MEMBRANES.
IN A PERSON OF LOW ZINC STATUS NOT ALL ORGANS GET THEIR OPTIMUM LEVEL DUE TO A @UIRK OF THEIR METABOLISM. WHEN THIS OCCURS AND THE MASAL @UCOSA ARE AFFECTE@ A@ INABILITY TO RESIST VIRSUSES EXISTS.
DES@ITE ACTIVE RESEARCH, THE METABOLIC ORIGINS OF THE @ATHOLIGICAL CHANGES CAUSED BY ZINC DEFICIENCY ARE @OORLY UNDERSTOOD. DIAG@DSTIC CRI@@RIA IS IAC@ING FOR MARGINAL DEFIC@HNCY AND THERE IS ALMOST NO SOIE@TIFIC DATA @@R SE@TING R@COMMENDATIONS FOR ZINC INTAKE.
ZINC HAS A VITAL ROLE IN THE STRUCTURE AND FUNCTIONS OF THE BODY AND IS ESSENTIAL. FOR THE IMM@@E DEFENCE SYSTEM, IN FACE, FRC@T LINE WHERE AIRBO@R@E VIRUSES ARE CO@C@R@ED AT THE SITHS OF INFECTION.
S@B @@TIMAL ZINC LEVELS IN EXPERIMENTAL ANIMALS CAUSED A REDUCTION IN LEUCOCYTES DUE TO WASTING OF THE THYMUS GLAND. HOWEVER, LEUCOCYTES ARE NOT INVOLVED IN RESISTANCE TO COLDS.
THE MECH@@ISMS FOR ZINC ABSORBTION AND THE FACTORS CONTRCILING IT ARE @OORLY UND@RST@OD . ONE DIETARY FACTOR KMOWN TO AFFECT ZINC APSORBTION IS @HY@IC ACID. CHIS IS FO@D IN WHOLEGRAIN CEREALS, LEGUMES , @HCIEMEA@ BREA@, SOY FORM@IA AND OTHER VEGETABLES.
AT THE @h VALUES FOU@I I@ FOODS, PHYTIC ACID WILL BE MEGATIVELY CHARGED AND WILL BIND TO POSITIVELY CHARGED MOLECULES SUCH AS ZINC AND SO IMPAIR THEIR ABSORBTION.
THE COMPOUND ENABLES A HIGHER STANDING LEVEL OF ZINC TO EXIST IN THE BODY THAN WOULD OTHERWISE BE THE CASE.
LO'T ZI?C STATUS IS DUE TO MALABSORBTION WHEN DIET IS DiOT IS NOT THE CAUSE. HIGHER DIETARY INTAKE EVEN INCLUDING SUPPLEMENTS MAKES LITTLE OR NO DIFFERENCE.
THIS IS DUE IN THE MAIN TO THE LARGE ZINC MOLECULES BEING UNABLE TO DIFFUSE THROUGH THE GUT WALL AND SO GOING TO WASTE.
AMINO ACID CHELATION INVOLVES CHEMICAL CLEAVAGE OF THE ZINC MOLECULES AND SURROUNDING THEM WITH AND BONDING THEN TO AMINO ACIDS IN A STABLE FORM FROM RICE PROTEIN. THIS PROVIDES A MATURAL MEANS FOR TRANSPORT ACROSS THE GUT AND IMCREASES THE AVAILABILITY TO THE BODY.
THE ASCORBIC ACID AND ACETYL SALYCYCLIC IMPROVE THE TRANSPORT TO AND CONDITION OF THE NASAL MUCOSA AND OFFERS A SOUND MEMBRANE FOR THE DIFFUSION OF THE ZINC. THE AGGREGATE BECOMES AN INTERACTIVE MIXTURE WITH A CONSEQUENT SYNERGISTIC EFFECT.
DESPITE THE MANUFACTURERS ASSERTION OF HIGHER TRANSIENT ZINC LEVELS IT IS NOT ENOUGH TO RAISE THEM TO OPTIMUM IN THE BODY WITHOUT THE SALICYCLIC ACID AND ASCORBIC TO COMPLETE THE REACTION. AMINO ACIDS ARE 95% ABSORBED WHEREAS DIETARY ZINC CAN BE AS LOW AS 5% .
EXACTLY WHAT HAPPENS AT THE MEMBRANE SURFACE WHEN VIRUSES ARE NEUTRALISED IS NOT KNOWN, BUT THERE ARE OPTIONS .
THE ZINC IS TOXIC TO THE VIRUSES THE ZINC REPELS THE VIRUSES WITH IT'S POSITIVE CHARGE. THE ZINC INCREASES THE SURFACE TENSION OF THE MEMBRANE, SO PREVENTING THE VIRUSES FROM PENETRATING.
CHELATION.
THE BODY IS VERY EFFICIENT AT ABSORBING AMINO ACIDS WITH A.
RATE OF 95 per cent. CHELATING TRACE ELEMENTS TO THESE ACIDS ALLOWS THEM TO BE DIFFUSED IN THE TRANSPORT PROCESS ACROSS THE GUT WALL.
SPECIAL PROCESSES ARE PERFORMED WHICH CREATES A STABLE ( COVALENT ) BOND WHICH IS IMPORTANT TO SECURE A HIGH RATE OF AVAILABILITY.
LARGE PARTICLES CANNOT EASILY PASS THROUGH THE GUT WALL AND MANY TRACE ELEMENTS HAVE MOLECULAR WEIGHTS TO LARGE TO BE ABSORBED INTACT.
THE PROCESS OFFERS ph BUFFERED STABILITY OF THE ELEMENTS. STABILITY IS MAINTAINED EVEN IN THE ACIDIC ENVIRONMENT OF DIGESTION ph@l.
ESSENTIALLY, CHELATING TURNS INORGANIC MINERALS INTO SMALL ORGANIC MOLECULES. THIS MAKES THEM MORE AVAILABLE AS THEY REMAIN INTACT AND DURABLE THROUGH DIGESTION.
THE SCIENTIFIC DEFINITION OF METAL AMINO ACID CHELATES IS , THE PRODUCT RESULTING FROM THE REACTION OF A METAL ION WITH AMINO ACIDS HAVING A MOLE RATIO OF ONE MOLE OF METAL TO ONE TO THREE MOLES OF AMINO ACIDS TO FORM COORDINATE COVALENT BONDS. THE RESULTING MOLECULE HAS TWO OR THREE FIVE-MEMBER HETEROCYCLIC RING STRUCTURES CONTAINING A METAL ION ( AS THE CLOSING MEMBER OF THE RING ). THE METAL ION IS ATTACHED BY COORDINATE COVALENT BONDS TO TWO OR MORE NON METALS IN THE SAME MOLECULE.
DESCRIPTION.
A PHARMACEUTICAL COMPOUND WITH THREE COMPONENTS WHICH IS AN EFFECTIVE PROPHYLACTIC FOR THE COMMON COLD (CORYZA).
A PHARMACEUTICAL COMPOSITION COMPRISING 50 to 100 mgs OF ASCORBIC ACID 15 to 30 mgs OF AMINO ACID CHELATED ZINC 300 mgs ASPIRIN - IN DRY POWDER FORM AS TABLETS OR CAPSULES .
DOSAGE IS.ANY COMBINATION OF THE ABOVE IN THE PREFERRED FORM. TAKEN DAILY, WITH.@SPIRIN LIMITED TO 300 mgs PER DAY.

Claims (1)

  1. CLAIM.
    A PHARMACEUTICAL COMPOUND FOR PREVENTING THE COMMON COLD AS CLAIMED IN CLAIM 1 AND COMPRISING A MIXTURE OF 100 mgs ASCORBIC ACID, 15 mgs AMINO ACID CHELATED ZINC AND 300 mgs ASPIRIN.
    THE NOVELTY OF THE CLAIM IS IN THE COMBINATION OF THE THREE ELEMENTS AND THE CHOICE OF THE INGREDIENTS IN THE CORRECT QUANTITIES.
    Amendments to the claims have been filed as follows CLAIM A PHARMACEUTICAL COMPOUND - SPECIFIC NAME 'ARMOUR' WHICH IS EFFECTIVE AGAINST CERTAIN VIRUS CAUSED ILLNESSES BOTH AS A PREVENTATIVE AND AS A CONTROL.
    IT IS A PREVENTATIVE FOR THE COMMON COLD.
    IT IS A PREVENTATIVE FOR HERPES SIMPLEX.
    IT WILL CONTROL HERPES SIMPLEX..
    IT IS A PREVENTATIVE FOR AN ENLARGED PROSTATE GLAND.
    iT WILL NORMALISE AN ENLARGED PROSTATE GLAND.
    THE COMPOUND IS COMPRISED OF 100mgs. ASCORBIC ACID, 15.30 mgs. CHELATED ZINC AND 1-300mg. ASPR[N. THE NOVELTY OF THE CLAIM IS IN THE COMBINATION OF THE THREE ELEMENTS, THE CHOICE OF THE [NGREDIENTS IN THE SPECIFIED QUANTITIES AND THE USE OF S.T.I. (STOMACH TISSUE INFILTRATION) TO ACHIEVE THE RESULTS.
GB9702528A 1997-02-07 1997-02-07 A zinc containing composition as a common cold prophylactic Expired - Fee Related GB2306109B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9702528A GB2306109B (en) 1997-02-07 1997-02-07 A zinc containing composition as a common cold prophylactic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9702528A GB2306109B (en) 1997-02-07 1997-02-07 A zinc containing composition as a common cold prophylactic

Publications (5)

Publication Number Publication Date
GB9702528D0 GB9702528D0 (en) 1997-03-26
GB2306109A true GB2306109A (en) 1997-04-30
GB2306109A9 GB2306109A9 (en) 1997-06-10
GB2306109A8 GB2306109A8 (en) 1997-06-10
GB2306109B GB2306109B (en) 1997-09-24

Family

ID=10807250

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9702528A Expired - Fee Related GB2306109B (en) 1997-02-07 1997-02-07 A zinc containing composition as a common cold prophylactic

Country Status (1)

Country Link
GB (1) GB2306109B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1003370A1 (en) * 1997-06-27 2000-05-31 Michael W. Dixon Method of enhancing magnesium absorption and prevention of atherosclerosis
WO2001028566A1 (en) * 1999-10-19 2001-04-26 Instituto Helmaprost, S.L. Use of acetyl salicilyc acid for the treatment of benign prostate hyperplasia
WO2001030324A2 (en) * 1999-10-27 2001-05-03 Aufsess Joachim G Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia
EP1447450A1 (en) * 2001-09-27 2004-08-18 Dnavec Research Inc. Method of regulating expression of gene carried on viral vector
WO2004110463A1 (en) * 2003-06-06 2004-12-23 The Procter & Gamble Company Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc
WO2008129270A2 (en) * 2007-04-18 2008-10-30 Renaissance Pharma Ltd Compositions comprising anti-inflammatory compounds
US7846914B2 (en) * 2001-09-07 2010-12-07 Advanced Medical Instruments Composition for the treatment and prevention of endothelial dysfunction
RU2524304C2 (en) * 2008-01-14 2014-07-27 Фенталеон Гмбх Application of acetylsalicylic acid salt for treatment of viral infections

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092978A (en) * 1965-07-30 1967-11-29 Analyses Et De Rech S Biolog M Novel analgesic and antipyretic medicinal compositions
EP0402078A2 (en) * 1989-06-06 1990-12-12 Patrick Daniel Kelly Sexual lubricants containing zinc as an anti-viral agent
WO1993001817A1 (en) * 1991-07-25 1993-02-04 Charles Lwanga Ssali Antiviral compositions comprising fusidic acid, l-ascorbic acid and salicylic acid and derivatives
CA2123935A1 (en) * 1993-06-04 1994-12-05 Jeffry W. Kreamer Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092978A (en) * 1965-07-30 1967-11-29 Analyses Et De Rech S Biolog M Novel analgesic and antipyretic medicinal compositions
EP0402078A2 (en) * 1989-06-06 1990-12-12 Patrick Daniel Kelly Sexual lubricants containing zinc as an anti-viral agent
WO1993001817A1 (en) * 1991-07-25 1993-02-04 Charles Lwanga Ssali Antiviral compositions comprising fusidic acid, l-ascorbic acid and salicylic acid and derivatives
CA2123935A1 (en) * 1993-06-04 1994-12-05 Jeffry W. Kreamer Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1003370A4 (en) * 1997-06-27 2004-04-21 Michael W Dixon Method of enhancing magnesium absorption and prevention of atherosclerosis
EP1003370A1 (en) * 1997-06-27 2000-05-31 Michael W. Dixon Method of enhancing magnesium absorption and prevention of atherosclerosis
WO2001028566A1 (en) * 1999-10-19 2001-04-26 Instituto Helmaprost, S.L. Use of acetyl salicilyc acid for the treatment of benign prostate hyperplasia
WO2001030324A2 (en) * 1999-10-27 2001-05-03 Aufsess Joachim G Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia
WO2001030324A3 (en) * 1999-10-27 2001-11-22 Joachim G Aufsess Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia
US7846914B2 (en) * 2001-09-07 2010-12-07 Advanced Medical Instruments Composition for the treatment and prevention of endothelial dysfunction
EP1447450A1 (en) * 2001-09-27 2004-08-18 Dnavec Research Inc. Method of regulating expression of gene carried on viral vector
EP1447450A4 (en) * 2001-09-27 2005-02-16 Dnavec Research Inc Method of regulating expression of gene carried on viral vector
WO2004110463A1 (en) * 2003-06-06 2004-12-23 The Procter & Gamble Company Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc
AU2004247082B2 (en) * 2003-06-06 2008-04-24 The Procter & Gamble Company Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc
WO2008129270A2 (en) * 2007-04-18 2008-10-30 Renaissance Pharma Ltd Compositions comprising anti-inflammatory compounds
WO2008129270A3 (en) * 2007-04-18 2008-12-18 Renaissance Pharma Ltd Compositions comprising anti-inflammatory compounds
RU2524304C2 (en) * 2008-01-14 2014-07-27 Фенталеон Гмбх Application of acetylsalicylic acid salt for treatment of viral infections
US9492413B2 (en) 2008-01-14 2016-11-15 Ventaleon Gmbh Use of salt of an acetylsalicylic acid for the treatment of viral infections

Also Published As

Publication number Publication date
GB2306109A9 (en) 1997-06-10
GB2306109A8 (en) 1997-06-10
GB9702528D0 (en) 1997-03-26
GB2306109B (en) 1997-09-24

Similar Documents

Publication Publication Date Title
Alkim et al. Role of bismuth in the eradication of Helicobacter pylori
CA1202906A (en) Composition and method for treating alcohol and drug addicts
US5614224A (en) Nutritional supplement for diabetics
CA2539567C (en) Nutritional and therapeutic compositions to increase bodily glutathione levels
Yanardag et al. Combined effects of vitamin C, vitamin E, and sodium selenate supplementation on absolute ethanol-induced injury in various organs of rats
GB2306109A (en) A zinc containing composition for treating the common cold
AU2003274071A1 (en) Dosage form that is safeguarded from abuse
Ni et al. Inhibitory effect of corosolic acid on α‐glucosidase: kinetics, interaction mechanism, and molecular simulation
Bishayee et al. Time course effects of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity
US5989560A (en) Herbal intestinal tract cleanser
Davis et al. Effects of over-the-counter drugs on 51chromium retention and urinary excretion in rats
Yanagisawa et al. Zinc physiology and clinical practice
US6932987B1 (en) Chemical composition and method for enhancing metabolism
Soar A cost-effective preventative approach to potentially save lives in the coronavirus pandemic, jointly using Vitamin D, Curcumin, and Vitamin C,(with updated dosage parameters). Bakare, T A., a and Soar, JS b
US20070184153A1 (en) Multiple antioxidant optimal health/veterans ultimate complete formulations
Jukes Megavitamin therapy
Yamaoka et al. A case of esophageal perforation due to a pill-induced ulcer successfully treated with conservative measures.
WO2017024639A1 (en) Chinese medicine hangover curing agent
Cathcart III The vitamin C treatment of allergy and the normally unprimed state of antibodies
US9226906B2 (en) Method and nutritional supplement for enhancing weight gain of a mammal
Pistos et al. Bioequivalence evaluation of two brands of glimepiride 4 mg tablets in healthy subjects.
Liu The Top 10 Supplements to Lower Blood Sugar Levels
RU2662148C1 (en) Method of treatment of anemic syndrome in children associated with perioral impact of manganese and chloroform from drinking water
Cronin The chromium controversy
Amin et al. Sources, blood concentrations, and approaches for reducing exposure to lead: a critical appraisal on lead poisoning.

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20010207

728V Application for restoration filed (sect. 28/1977)
7281 Application for restoration withdrawn (sect. 28/1977)