GB2306109A - A zinc containing composition for treating the common cold - Google Patents
A zinc containing composition for treating the common cold Download PDFInfo
- Publication number
- GB2306109A GB2306109A GB9702528A GB9702528A GB2306109A GB 2306109 A GB2306109 A GB 2306109A GB 9702528 A GB9702528 A GB 9702528A GB 9702528 A GB9702528 A GB 9702528A GB 2306109 A GB2306109 A GB 2306109A
- Authority
- GB
- United Kingdom
- Prior art keywords
- zinc
- mgs
- preventative
- common cold
- ascorbic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
Abstract
The composition comprises amino acids, zinc, ascorbic acid (Vitamin C) and aspirin (acetylsalicylic acid). The amino acids, which are chelated by the zinc, promote zinc uptake across mucosal surfaces such as the gut. Vitamin C and aspirin are intended to promote intranasal uptake of the composition. The composition is in a dry powder form which may be incorporated into capsules or provided as a compressed tablet.
Description
RATIONALE FOR A COMMON COLD PROPHYLACTIC
THERE APPEARS TO BE NO RESEARCH DATA AVAILABLE WHICH DIFFERENTIATES
THE PHYSIOLOGICAL DIFFERENCE BETWEEN PERSONS WHO CATCH COLDS AND
THOSE WHO DO NOT. AND YET THIS UNDERSTANDING WHICH NEEDS TO BE
ESTABLISHED IS VITAL BECAUSE THE COMCLUSION TO BE DRAWN IS THAT
THE PERSON WHO DOES NOT CATCH COLD @OSSESSES ANTI - VIRAL QUALITIES.
THE RHINOVIRUS, WHICH IS RESPONSIBLE, HAS AT LEAST 100 VARIANTS
AND YET THAT PERSON RESISTS THEM ALL DES@ITE THEIR DIFFERENT@ CHARACTERISTICS. THE TAXONOMIC GROUPS OF VIRUSES ( FA@ILIES) NUMBER AT LEAST 18 AND THEY ARE ALSO DIVIDED IMTO SUB-FA@ILIES AND
THOSE INTO VARIANTS.
ALL VIRUSES ARE DIFFERENT FROM EACH OTHER, IN SIZE, CONSTRUCTION, AND
CONTENTS. IN ORDER TO EFFECT ENTRY INTO A POTENTIAL HOST CELL THEY
EITHER INJECT OR INVADE.
HOWEVER, THE MODUS OPERANDI FOR ALL VIRUSES AT THE BEGINNING OF THE
CYCLE OF INFECTION COMMENCES WITH THE SAME TWO STEPS. THE FIRST
IS ASSIDENTAL- LANDING ON THE CELL. THE SECOND INVOLVES ATTACHING
TO THE CELL SURFACE (ADSORBTION). AS VIRUSES ARE PARASITES THIS
STEP IS VITAL IF THEY ARE TO PROCEED TO STEP THREE.
IT IS OBVIOUS FROM THIS THAT IF THOSE FIRST TWO STEPS CAN BE
PREVENTED, THE VIRUS WILL BE MEUTRALISED. DENY THEM ACCESS TO THE
NASAL MUCOSA AND THEY WILL REMAIN PASSIVE.
A PERSON WITH THIS ABILITY MUST BE DEEMED IMPERVIOUS TO VIRUSES A'1' THAT SIR OF INFECTION.
ESSENTIALY THE COMMON COLD IS A LOCAL AND SUPERFICIAL RESPONSE TO THE VIRUS, SOMEWHAT SIMILAR TO THAT CAUSED BY POLLEN AND
PENETRATION TO THE BLOODSTREAM DOES NOT TAKE PLACE.
THEREFORE A T OR B CELL RESPONSE IS NOT INVOLVED.
ZINC IS NOT A NUTRIENT AS SUCH BUT IT IS VITAL IN THE STANDING FLUIDS
OF THE BODY. IT IS PRESENT IN THE S@IN AND PERSPIRATION, IN THE
PROSTATIC FLUIDS INCLUDING SEMEN, IN THE EYES AND BRAIN AND THE
INTERNAL SURFACES SUCH AS THE MUCOUS MEMBRANES.
IN A PERSON OF LOW ZINC STATUS NOT ALL ORGANS GET THEIR OPTIMUM LEVEL
DUE TO A @UIRK OF THEIR METABOLISM. WHEN THIS OCCURS AND THE MASAL @UCOSA ARE AFFECTE@ A@ INABILITY TO RESIST VIRSUSES EXISTS.
DES@ITE ACTIVE RESEARCH, THE METABOLIC ORIGINS OF THE @ATHOLIGICAL CHANGES CAUSED BY ZINC DEFICIENCY ARE @OORLY UNDERSTOOD. DIAG@DSTIC CRI@@RIA IS IAC@ING FOR MARGINAL DEFIC@HNCY AND THERE IS ALMOST NO SOIE@TIFIC DATA @@R SE@TING R@COMMENDATIONS FOR ZINC INTAKE.
ZINC HAS A VITAL ROLE IN THE STRUCTURE AND FUNCTIONS OF THE BODY AND
IS ESSENTIAL. FOR THE IMM@@E DEFENCE SYSTEM, IN FACE, FRC@T LINE WHERE AIRBO@R@E VIRUSES ARE CO@C@R@ED AT THE SITHS OF INFECTION.
S@B @@TIMAL ZINC LEVELS IN EXPERIMENTAL ANIMALS CAUSED A REDUCTION IN LEUCOCYTES DUE TO WASTING OF THE THYMUS GLAND. HOWEVER, LEUCOCYTES ARE
NOT INVOLVED IN RESISTANCE TO COLDS.
THE MECH@@ISMS FOR ZINC ABSORBTION AND THE FACTORS CONTRCILING IT
ARE @OORLY UND@RST@OD . ONE DIETARY FACTOR KMOWN TO AFFECT ZINC
APSORBTION IS @HY@IC ACID. CHIS IS FO@D IN WHOLEGRAIN CEREALS, LEGUMES , @HCIEMEA@ BREA@, SOY FORM@IA AND OTHER VEGETABLES.
AT THE @h VALUES FOU@I I@ FOODS, PHYTIC ACID WILL BE MEGATIVELY
CHARGED AND WILL BIND TO POSITIVELY CHARGED MOLECULES SUCH AS ZINC
AND SO IMPAIR THEIR ABSORBTION.
THE COMPOUND ENABLES A HIGHER STANDING LEVEL OF ZINC TO EXIST IN
THE BODY THAN WOULD OTHERWISE BE THE CASE.
LO'T ZI?C STATUS IS DUE TO MALABSORBTION WHEN DIET IS DiOT IS NOT
THE CAUSE. HIGHER DIETARY INTAKE EVEN INCLUDING SUPPLEMENTS
MAKES LITTLE OR NO DIFFERENCE.
THIS IS DUE IN THE MAIN TO THE LARGE ZINC MOLECULES BEING UNABLE
TO DIFFUSE THROUGH THE GUT WALL AND SO GOING TO WASTE.
AMINO ACID CHELATION INVOLVES CHEMICAL CLEAVAGE OF THE ZINC
MOLECULES AND SURROUNDING THEM WITH AND BONDING THEN TO AMINO
ACIDS IN A STABLE FORM FROM RICE PROTEIN. THIS PROVIDES A MATURAL
MEANS FOR TRANSPORT ACROSS THE GUT AND IMCREASES THE AVAILABILITY
TO THE BODY.
THE ASCORBIC ACID AND ACETYL SALYCYCLIC IMPROVE THE TRANSPORT TO
AND CONDITION OF THE NASAL MUCOSA AND OFFERS A SOUND MEMBRANE FOR
THE DIFFUSION OF THE ZINC. THE AGGREGATE BECOMES AN INTERACTIVE
MIXTURE WITH A CONSEQUENT SYNERGISTIC EFFECT.
DESPITE THE MANUFACTURERS ASSERTION OF HIGHER TRANSIENT ZINC
LEVELS IT IS NOT ENOUGH TO RAISE THEM TO OPTIMUM IN THE BODY
WITHOUT THE SALICYCLIC ACID AND ASCORBIC TO COMPLETE THE REACTION. AMINO ACIDS ARE 95% ABSORBED WHEREAS DIETARY ZINC
CAN BE AS LOW AS 5% .
EXACTLY WHAT HAPPENS AT THE MEMBRANE SURFACE WHEN VIRUSES ARE
NEUTRALISED IS NOT KNOWN, BUT THERE ARE OPTIONS .
THE ZINC IS TOXIC TO THE VIRUSES THE ZINC REPELS THE VIRUSES
WITH IT'S POSITIVE CHARGE. THE ZINC INCREASES THE SURFACE TENSION
OF THE MEMBRANE, SO PREVENTING THE VIRUSES FROM PENETRATING.
CHELATION.
THE BODY IS VERY EFFICIENT AT ABSORBING AMINO ACIDS WITH A.
RATE OF 95 per cent. CHELATING TRACE ELEMENTS TO THESE ACIDS ALLOWS
THEM TO BE DIFFUSED IN THE TRANSPORT PROCESS ACROSS THE GUT WALL.
SPECIAL PROCESSES ARE PERFORMED WHICH CREATES A STABLE ( COVALENT )
BOND WHICH IS IMPORTANT TO SECURE A HIGH RATE OF AVAILABILITY.
LARGE PARTICLES CANNOT EASILY PASS THROUGH THE GUT WALL AND MANY
TRACE ELEMENTS HAVE MOLECULAR WEIGHTS TO LARGE TO BE ABSORBED INTACT.
THE PROCESS OFFERS ph BUFFERED STABILITY OF THE ELEMENTS. STABILITY
IS MAINTAINED EVEN IN THE ACIDIC ENVIRONMENT OF DIGESTION ph@l.
ESSENTIALLY, CHELATING TURNS INORGANIC MINERALS INTO SMALL ORGANIC
MOLECULES. THIS MAKES THEM MORE AVAILABLE AS THEY REMAIN INTACT AND
DURABLE THROUGH DIGESTION.
THE SCIENTIFIC DEFINITION OF METAL AMINO ACID CHELATES IS , THE
PRODUCT RESULTING FROM THE REACTION OF A METAL ION WITH AMINO ACIDS
HAVING A MOLE RATIO OF ONE MOLE OF METAL TO ONE TO THREE MOLES OF
AMINO ACIDS TO FORM COORDINATE COVALENT BONDS. THE RESULTING
MOLECULE HAS TWO OR THREE FIVE-MEMBER HETEROCYCLIC RING STRUCTURES
CONTAINING A METAL ION ( AS THE CLOSING MEMBER OF THE RING ). THE
METAL ION IS ATTACHED BY COORDINATE COVALENT BONDS TO TWO OR MORE
NON METALS IN THE SAME MOLECULE.
DESCRIPTION.
A PHARMACEUTICAL COMPOUND WITH THREE COMPONENTS
WHICH IS AN EFFECTIVE PROPHYLACTIC FOR THE
COMMON COLD (CORYZA).
A PHARMACEUTICAL COMPOSITION COMPRISING 50 to 100 mgs OF ASCORBIC ACID 15 to 30 mgs OF AMINO ACID CHELATED ZINC 300 mgs ASPIRIN - IN DRY POWDER FORM AS TABLETS OR CAPSULES .
DOSAGE IS.ANY COMBINATION OF THE ABOVE IN
THE PREFERRED FORM. TAKEN DAILY, WITH.@SPIRIN LIMITED TO 300 mgs PER DAY.
Claims (1)
- CLAIM.A PHARMACEUTICAL COMPOUND FOR PREVENTING THE COMMON COLD AS CLAIMED IN CLAIM 1 AND COMPRISING A MIXTURE OF 100 mgs ASCORBIC ACID, 15 mgs AMINO ACID CHELATED ZINC AND 300 mgs ASPIRIN.THE NOVELTY OF THE CLAIM IS IN THE COMBINATION OF THE THREE ELEMENTS AND THE CHOICE OF THE INGREDIENTS IN THE CORRECT QUANTITIES.Amendments to the claims have been filed as follows CLAIM A PHARMACEUTICAL COMPOUND - SPECIFIC NAME 'ARMOUR' WHICH IS EFFECTIVE AGAINST CERTAIN VIRUS CAUSED ILLNESSES BOTH AS A PREVENTATIVE AND AS A CONTROL.IT IS A PREVENTATIVE FOR THE COMMON COLD.IT IS A PREVENTATIVE FOR HERPES SIMPLEX.IT WILL CONTROL HERPES SIMPLEX..IT IS A PREVENTATIVE FOR AN ENLARGED PROSTATE GLAND.iT WILL NORMALISE AN ENLARGED PROSTATE GLAND.THE COMPOUND IS COMPRISED OF 100mgs. ASCORBIC ACID, 15.30 mgs. CHELATED ZINC AND 1-300mg. ASPR[N. THE NOVELTY OF THE CLAIM IS IN THE COMBINATION OF THE THREE ELEMENTS, THE CHOICE OF THE [NGREDIENTS IN THE SPECIFIED QUANTITIES AND THE USE OF S.T.I. (STOMACH TISSUE INFILTRATION) TO ACHIEVE THE RESULTS.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9702528A GB2306109B (en) | 1997-02-07 | 1997-02-07 | A zinc containing composition as a common cold prophylactic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9702528A GB2306109B (en) | 1997-02-07 | 1997-02-07 | A zinc containing composition as a common cold prophylactic |
Publications (5)
Publication Number | Publication Date |
---|---|
GB9702528D0 GB9702528D0 (en) | 1997-03-26 |
GB2306109A true GB2306109A (en) | 1997-04-30 |
GB2306109A9 GB2306109A9 (en) | 1997-06-10 |
GB2306109A8 GB2306109A8 (en) | 1997-06-10 |
GB2306109B GB2306109B (en) | 1997-09-24 |
Family
ID=10807250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9702528A Expired - Fee Related GB2306109B (en) | 1997-02-07 | 1997-02-07 | A zinc containing composition as a common cold prophylactic |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2306109B (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1003370A1 (en) * | 1997-06-27 | 2000-05-31 | Michael W. Dixon | Method of enhancing magnesium absorption and prevention of atherosclerosis |
WO2001028566A1 (en) * | 1999-10-19 | 2001-04-26 | Instituto Helmaprost, S.L. | Use of acetyl salicilyc acid for the treatment of benign prostate hyperplasia |
WO2001030324A2 (en) * | 1999-10-27 | 2001-05-03 | Aufsess Joachim G | Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia |
EP1447450A1 (en) * | 2001-09-27 | 2004-08-18 | Dnavec Research Inc. | Method of regulating expression of gene carried on viral vector |
WO2004110463A1 (en) * | 2003-06-06 | 2004-12-23 | The Procter & Gamble Company | Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc |
WO2008129270A2 (en) * | 2007-04-18 | 2008-10-30 | Renaissance Pharma Ltd | Compositions comprising anti-inflammatory compounds |
US7846914B2 (en) * | 2001-09-07 | 2010-12-07 | Advanced Medical Instruments | Composition for the treatment and prevention of endothelial dysfunction |
RU2524304C2 (en) * | 2008-01-14 | 2014-07-27 | Фенталеон Гмбх | Application of acetylsalicylic acid salt for treatment of viral infections |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1092978A (en) * | 1965-07-30 | 1967-11-29 | Analyses Et De Rech S Biolog M | Novel analgesic and antipyretic medicinal compositions |
EP0402078A2 (en) * | 1989-06-06 | 1990-12-12 | Patrick Daniel Kelly | Sexual lubricants containing zinc as an anti-viral agent |
WO1993001817A1 (en) * | 1991-07-25 | 1993-02-04 | Charles Lwanga Ssali | Antiviral compositions comprising fusidic acid, l-ascorbic acid and salicylic acid and derivatives |
CA2123935A1 (en) * | 1993-06-04 | 1994-12-05 | Jeffry W. Kreamer | Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease |
-
1997
- 1997-02-07 GB GB9702528A patent/GB2306109B/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1092978A (en) * | 1965-07-30 | 1967-11-29 | Analyses Et De Rech S Biolog M | Novel analgesic and antipyretic medicinal compositions |
EP0402078A2 (en) * | 1989-06-06 | 1990-12-12 | Patrick Daniel Kelly | Sexual lubricants containing zinc as an anti-viral agent |
WO1993001817A1 (en) * | 1991-07-25 | 1993-02-04 | Charles Lwanga Ssali | Antiviral compositions comprising fusidic acid, l-ascorbic acid and salicylic acid and derivatives |
CA2123935A1 (en) * | 1993-06-04 | 1994-12-05 | Jeffry W. Kreamer | Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1003370A4 (en) * | 1997-06-27 | 2004-04-21 | Michael W Dixon | Method of enhancing magnesium absorption and prevention of atherosclerosis |
EP1003370A1 (en) * | 1997-06-27 | 2000-05-31 | Michael W. Dixon | Method of enhancing magnesium absorption and prevention of atherosclerosis |
WO2001028566A1 (en) * | 1999-10-19 | 2001-04-26 | Instituto Helmaprost, S.L. | Use of acetyl salicilyc acid for the treatment of benign prostate hyperplasia |
WO2001030324A2 (en) * | 1999-10-27 | 2001-05-03 | Aufsess Joachim G | Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia |
WO2001030324A3 (en) * | 1999-10-27 | 2001-11-22 | Joachim G Aufsess | Use of acetylsalicylic acid and a preparation for treatment of prostatic hyperplasia |
US7846914B2 (en) * | 2001-09-07 | 2010-12-07 | Advanced Medical Instruments | Composition for the treatment and prevention of endothelial dysfunction |
EP1447450A1 (en) * | 2001-09-27 | 2004-08-18 | Dnavec Research Inc. | Method of regulating expression of gene carried on viral vector |
EP1447450A4 (en) * | 2001-09-27 | 2005-02-16 | Dnavec Research Inc | Method of regulating expression of gene carried on viral vector |
WO2004110463A1 (en) * | 2003-06-06 | 2004-12-23 | The Procter & Gamble Company | Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc |
AU2004247082B2 (en) * | 2003-06-06 | 2008-04-24 | The Procter & Gamble Company | Compositions for prevention and treatment of cold and influenza-like symptoms comprising chelated zinc |
WO2008129270A2 (en) * | 2007-04-18 | 2008-10-30 | Renaissance Pharma Ltd | Compositions comprising anti-inflammatory compounds |
WO2008129270A3 (en) * | 2007-04-18 | 2008-12-18 | Renaissance Pharma Ltd | Compositions comprising anti-inflammatory compounds |
RU2524304C2 (en) * | 2008-01-14 | 2014-07-27 | Фенталеон Гмбх | Application of acetylsalicylic acid salt for treatment of viral infections |
US9492413B2 (en) | 2008-01-14 | 2016-11-15 | Ventaleon Gmbh | Use of salt of an acetylsalicylic acid for the treatment of viral infections |
Also Published As
Publication number | Publication date |
---|---|
GB2306109A9 (en) | 1997-06-10 |
GB2306109A8 (en) | 1997-06-10 |
GB9702528D0 (en) | 1997-03-26 |
GB2306109B (en) | 1997-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20010207 |
|
728V | Application for restoration filed (sect. 28/1977) | ||
7281 | Application for restoration withdrawn (sect. 28/1977) |