GB2251242B - Protecting compound - Google Patents

Protecting compound

Info

Publication number
GB2251242B
GB2251242B GB9028208A GB9028208A GB2251242B GB 2251242 B GB2251242 B GB 2251242B GB 9028208 A GB9028208 A GB 9028208A GB 9028208 A GB9028208 A GB 9028208A GB 2251242 B GB2251242 B GB 2251242B
Authority
GB
United Kingdom
Prior art keywords
group
protecting compound
protected
bonding
following formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9028208A
Other versions
GB9028208D0 (en
GB2251242A (en
Inventor
Robert Ramage
Giles Raphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB9028208A priority Critical patent/GB2251242B/en
Publication of GB9028208D0 publication Critical patent/GB9028208D0/en
Priority to AU91707/91A priority patent/AU669324B2/en
Priority to CA002099120A priority patent/CA2099120A1/en
Priority to KR1019930701991A priority patent/KR100232396B1/en
Priority to ES92903453T priority patent/ES2133313T3/en
Priority to AT92903453T priority patent/ATE179180T1/en
Priority to PCT/FR1991/001083 priority patent/WO1992012167A1/en
Priority to EP92903453A priority patent/EP0565607B1/en
Priority to DK92903453T priority patent/DK0565607T3/en
Priority to HU9301892A priority patent/HU217033B/en
Priority to BR9107286A priority patent/BR9107286A/en
Priority to JP50327292A priority patent/JP3286316B2/en
Priority to DE69131168T priority patent/DE69131168T2/en
Publication of GB2251242A publication Critical patent/GB2251242A/en
Application granted granted Critical
Publication of GB2251242B publication Critical patent/GB2251242B/en
Priority to US09/162,777 priority patent/US6359113B1/en
Priority to GR990401250T priority patent/GR3030169T3/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/54—Ortho- or ortho- and peri-condensed systems containing more than five condensed rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Coupling Device And Connection With Printed Circuit (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Inorganic Insulating Materials (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Container Filling Or Packaging Operations (AREA)
  • Packages (AREA)

Abstract

The protection group has the following formula (I): Ar-L- where Ar represents a substantially flat system of fused rings containing at least 4 aromatic rings, and L represents a group containing at least one carbon atom capable of bonding to a group to be protected.
GB9028208A 1990-12-31 1990-12-31 Protecting compound Expired - Fee Related GB2251242B (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GB9028208A GB2251242B (en) 1990-12-31 1990-12-31 Protecting compound
DK92903453T DK0565607T3 (en) 1990-12-31 1991-12-31 Protective group, compound protected with this group and device for grafting the protecting group onto the compound,
BR9107286A BR9107286A (en) 1990-12-31 1991-12-31 Protective compound group of protected compound protected device process for the synthesis or separation of a mixture of compounds and use of a group
KR1019930701991A KR100232396B1 (en) 1990-12-31 1991-12-31 Protection group compound protected by this group and device for grafting the protection group onto the compound being protected
ES92903453T ES2133313T3 (en) 1990-12-31 1991-12-31 PROTECTIVE GROUP, COMPOUND PROTECTED BY THIS GROUP AND DEVICE TO GRAFT THE PROTECTIVE GROUP IN THE COMPOUND THAT IT IS TRYING TO PROTECT.
AT92903453T ATE179180T1 (en) 1990-12-31 1991-12-31 PROTECTION GROUP, CONNECTION PROTECTED BY THIS GROUP, AND DEVICE FOR ATTACHING THE PROTECTION GROUP TO THE CONNECTION TO BE PROTECTED
PCT/FR1991/001083 WO1992012167A1 (en) 1990-12-31 1991-12-31 Protection group, compoud protected by this group and device for grafting the protection group onto the compound being protected
EP92903453A EP0565607B1 (en) 1990-12-31 1991-12-31 Protection group, compoud protected by this group and device for grafting the protection group onto the compound being protected
AU91707/91A AU669324B2 (en) 1990-12-31 1991-12-31 Protection group, compound protected by this group and device for grafting the protection group onto the compound being protected
HU9301892A HU217033B (en) 1990-12-31 1991-12-31 Protection group, compounds containing protection group, process and apparatus for using the protection group
CA002099120A CA2099120A1 (en) 1990-12-31 1991-12-31 Protection group, compound protected by this group and device for grafting the protection group onto the compound being protected
JP50327292A JP3286316B2 (en) 1990-12-31 1991-12-31 Protecting group
DE69131168T DE69131168T2 (en) 1990-12-31 1991-12-31 PROTECTIVE GROUP, CONNECTION PROTECTED BY THIS GROUP, AND DEVICE FOR ATTACHING THE PROTECTIVE GROUP TO THE CONNECTOR TO BE PROTECTED
US09/162,777 US6359113B1 (en) 1990-12-31 1998-09-30 Protective group, compound protected by said group and device for grafting the protective group on the compound to protect it
GR990401250T GR3030169T3 (en) 1990-12-31 1999-05-07 Protection group, compoud protected by this group and device for grafting the protection group onto the compound being protected

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9028208A GB2251242B (en) 1990-12-31 1990-12-31 Protecting compound

Publications (3)

Publication Number Publication Date
GB9028208D0 GB9028208D0 (en) 1991-02-13
GB2251242A GB2251242A (en) 1992-07-01
GB2251242B true GB2251242B (en) 1995-01-11

Family

ID=10687684

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9028208A Expired - Fee Related GB2251242B (en) 1990-12-31 1990-12-31 Protecting compound

Country Status (14)

Country Link
EP (1) EP0565607B1 (en)
JP (1) JP3286316B2 (en)
KR (1) KR100232396B1 (en)
AT (1) ATE179180T1 (en)
AU (1) AU669324B2 (en)
BR (1) BR9107286A (en)
CA (1) CA2099120A1 (en)
DE (1) DE69131168T2 (en)
DK (1) DK0565607T3 (en)
ES (1) ES2133313T3 (en)
GB (1) GB2251242B (en)
GR (1) GR3030169T3 (en)
HU (1) HU217033B (en)
WO (1) WO1992012167A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9307014D0 (en) * 1993-04-02 1993-05-26 Laporte Plc Protecting group for use in oligodeoxyribonucleotide synthesis
GB2299993A (en) * 1995-04-21 1996-10-23 Rhone Poulenc Ltd Chiral polycyclic aromatic compounds and their use as a chiral stationary phase in enantiomeric separations
DE102010001983A1 (en) * 2010-02-16 2011-08-18 peptides&elephants GmbH, 14558 A process for producing a graphite-based peptide purification material and process for peptide purification

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB272528A (en) * 1900-01-01
GB201786A (en) * 1922-08-24 1923-08-09 Kalle & Co Ag Process for producing vat colouring-matters
GB303389A (en) * 1927-07-01 1929-01-01 Ig Farbenindustrie Ag The manufacture of new carboxylic acids of the fatty-aromatic series
GB327526A (en) * 1929-02-27 1930-04-10 Ig Farbenindustrie Ag Manufacture of aralkyl-benzanthrones
GB469633A (en) * 1935-08-10 1937-07-29 Ig Farbenindustrie Ag The manufacture of polycyclic condensation products
GB824175A (en) * 1955-02-21 1959-11-25 Metal & Thermit Corp Reactions involving grignard reagents
GB1335606A (en) * 1970-07-21 1973-10-31 Bayer Ag Process for the production of acyl isocyanide dichlorides and carboxylic acid chlorides
EP0073007A1 (en) * 1981-08-24 1983-03-02 BASF Aktiengesellschaft Method for the square dimensional concentration of light, and fluorescent compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839396A (en) * 1971-07-15 1974-10-01 Shionogi & Co 9-lower alkyl-9-fluorenyl carbonates
DE3711866A1 (en) * 1987-04-08 1988-10-27 Hoechst Ag SYNTHESIS OF PEPTIDAMIDES BY SOLID PHASE METHOD USING SAEURELABILE ANCHOR GROUPS

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB272528A (en) * 1900-01-01
GB201786A (en) * 1922-08-24 1923-08-09 Kalle & Co Ag Process for producing vat colouring-matters
GB303389A (en) * 1927-07-01 1929-01-01 Ig Farbenindustrie Ag The manufacture of new carboxylic acids of the fatty-aromatic series
GB327526A (en) * 1929-02-27 1930-04-10 Ig Farbenindustrie Ag Manufacture of aralkyl-benzanthrones
GB469633A (en) * 1935-08-10 1937-07-29 Ig Farbenindustrie Ag The manufacture of polycyclic condensation products
GB824175A (en) * 1955-02-21 1959-11-25 Metal & Thermit Corp Reactions involving grignard reagents
GB1335606A (en) * 1970-07-21 1973-10-31 Bayer Ag Process for the production of acyl isocyanide dichlorides and carboxylic acid chlorides
EP0073007A1 (en) * 1981-08-24 1983-03-02 BASF Aktiengesellschaft Method for the square dimensional concentration of light, and fluorescent compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA 106 (5): 32511r *
CA 69 (15): 58881d *

Also Published As

Publication number Publication date
WO1992012167A1 (en) 1992-07-23
KR100232396B1 (en) 1999-12-01
ES2133313T3 (en) 1999-09-16
HUT69324A (en) 1995-09-28
GB9028208D0 (en) 1991-02-13
GR3030169T3 (en) 1999-08-31
JP3286316B2 (en) 2002-05-27
BR9107286A (en) 1996-01-02
ATE179180T1 (en) 1999-05-15
DK0565607T3 (en) 1999-10-25
HU217033B (en) 1999-11-29
AU669324B2 (en) 1996-06-06
CA2099120A1 (en) 1992-07-01
HU9301892D0 (en) 1993-09-28
KR930703346A (en) 1993-11-29
EP0565607B1 (en) 1999-04-21
DE69131168D1 (en) 1999-05-27
DE69131168T2 (en) 1999-11-18
GB2251242A (en) 1992-07-01
EP0565607A1 (en) 1993-10-20
AU9170791A (en) 1992-08-17
JPH06506914A (en) 1994-08-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20031231