GB2229725B - A method of enhancing neutralising antibody activity in human or animal sera or in other body secreations - Google Patents

A method of enhancing neutralising antibody activity in human or animal sera or in other body secreations

Info

Publication number
GB2229725B
GB2229725B GB9006608A GB9006608A GB2229725B GB 2229725 B GB2229725 B GB 2229725B GB 9006608 A GB9006608 A GB 9006608A GB 9006608 A GB9006608 A GB 9006608A GB 2229725 B GB2229725 B GB 2229725B
Authority
GB
United Kingdom
Prior art keywords
enhancing
human
secreations
antibody activity
neutralising antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9006608A
Other versions
GB9006608D0 (en
GB2229725A (en
Inventor
Gordon Robert Bruce Skinner
Alexander Buchan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research International Ltd Great Britain
Original Assignee
Medical Research International Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Research International Ltd Great Britain filed Critical Medical Research International Ltd Great Britain
Publication of GB9006608D0 publication Critical patent/GB9006608D0/en
Publication of GB2229725A publication Critical patent/GB2229725A/en
Application granted granted Critical
Publication of GB2229725B publication Critical patent/GB2229725B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/38Stomach; Intestine; Goblet cells; Oral mucosa; Saliva

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Neutralising antibody activity is enhanced by exposure of the antibody to an enhancing factor comprising or extracted from human or animal saliva or an enzyme for the digestion of carbohydrates which is not inimical to the neutralising antibody, for example amylase or lysozyme, in an antibody activity enhancing amount.
GB9006608A 1989-03-23 1990-03-23 A method of enhancing neutralising antibody activity in human or animal sera or in other body secreations Expired - Fee Related GB2229725B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898906796A GB8906796D0 (en) 1989-03-23 1989-03-23 Method of enhancing neutralising antibody activity in human or animal sera or in other body secretions

Publications (3)

Publication Number Publication Date
GB9006608D0 GB9006608D0 (en) 1990-05-23
GB2229725A GB2229725A (en) 1990-10-03
GB2229725B true GB2229725B (en) 1993-02-17

Family

ID=10653944

Family Applications (2)

Application Number Title Priority Date Filing Date
GB898906796A Pending GB8906796D0 (en) 1989-03-23 1989-03-23 Method of enhancing neutralising antibody activity in human or animal sera or in other body secretions
GB9006608A Expired - Fee Related GB2229725B (en) 1989-03-23 1990-03-23 A method of enhancing neutralising antibody activity in human or animal sera or in other body secreations

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB898906796A Pending GB8906796D0 (en) 1989-03-23 1989-03-23 Method of enhancing neutralising antibody activity in human or animal sera or in other body secretions

Country Status (1)

Country Link
GB (2) GB8906796D0 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL378216A1 (en) 2003-01-16 2006-03-20 Pedersen Medical A/S Antimicrobial composition for local use on mucosal membranes and skin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Dictionary of Immunology (1989, Macmillan Press)-Rosen et alp146 *
IMMUNOLOGY (1975) Vol.28 No.6 pp1061-1066 *

Also Published As

Publication number Publication date
GB8906796D0 (en) 1989-05-10
GB9006608D0 (en) 1990-05-23
GB2229725A (en) 1990-10-03

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950323