GB2194241B - Ribosome inactivating proteins. - Google Patents

Ribosome inactivating proteins.

Info

Publication number
GB2194241B
GB2194241B GB8717932A GB8717932A GB2194241B GB 2194241 B GB2194241 B GB 2194241B GB 8717932 A GB8717932 A GB 8717932A GB 8717932 A GB8717932 A GB 8717932A GB 2194241 B GB2194241 B GB 2194241B
Authority
GB
United Kingdom
Prior art keywords
ribosome inactivating
inactivating proteins
proteins
ribosome
inactivating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8717932A
Other languages
English (en)
Other versions
GB2194241A (en
GB8717932D0 (en
Inventor
Douglas Lappi
Pier Carlo Montecucchi
Marco Soria
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868618442A external-priority patent/GB8618442D0/en
Priority claimed from GB878709221A external-priority patent/GB8709221D0/en
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of GB8717932D0 publication Critical patent/GB8717932D0/en
Publication of GB2194241A publication Critical patent/GB2194241A/en
Application granted granted Critical
Publication of GB2194241B publication Critical patent/GB2194241B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
GB8717932A 1986-07-29 1987-07-29 Ribosome inactivating proteins. Expired - Fee Related GB2194241B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868618442A GB8618442D0 (en) 1986-07-29 1986-07-29 Inhibitor of protein synthesis
GB878709221A GB8709221D0 (en) 1987-04-16 1987-04-16 Immunotoxins

Publications (3)

Publication Number Publication Date
GB8717932D0 GB8717932D0 (en) 1987-09-03
GB2194241A GB2194241A (en) 1988-03-02
GB2194241B true GB2194241B (en) 1990-07-18

Family

ID=26291099

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8717932A Expired - Fee Related GB2194241B (en) 1986-07-29 1987-07-29 Ribosome inactivating proteins.

Country Status (3)

Country Link
DE (1) DE3724323C2 (de)
GB (1) GB2194241B (de)
IT (1) IT1231914B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8801877D0 (en) * 1988-01-28 1988-02-24 Erba Carlo Spa Nucleotide sequence encoding plant ribosome inactivating protein
US5529932A (en) * 1988-01-28 1996-06-25 Pharmacia, S.P.A. Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis
US5248606A (en) * 1990-06-11 1993-09-28 Dowelanco Dna encoding inactive precursor and active forms of maize ribosome inactivating protein
US5635384A (en) * 1990-06-11 1997-06-03 Dowelanco Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biochem. J. 1983, 216, 6 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival

Also Published As

Publication number Publication date
GB2194241A (en) 1988-03-02
GB8717932D0 (en) 1987-09-03
IT8721475A0 (it) 1987-07-28
DE3724323C2 (de) 1995-07-20
IT1231914B (it) 1992-01-15
DE3724323A1 (de) 1988-02-11

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950729