GB2193725A - Incubator - Google Patents

Incubator Download PDF

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Publication number
GB2193725A
GB2193725A GB08606479A GB8606479A GB2193725A GB 2193725 A GB2193725 A GB 2193725A GB 08606479 A GB08606479 A GB 08606479A GB 8606479 A GB8606479 A GB 8606479A GB 2193725 A GB2193725 A GB 2193725A
Authority
GB
United Kingdom
Prior art keywords
incubator
housing
door
foil
oven according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08606479A
Other versions
GB8606479D0 (en
Inventor
Richard Harry Mark Freeman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda Pharmaceuticals Ltd
Original Assignee
Flow Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flow Labs Ltd filed Critical Flow Labs Ltd
Priority to GB08606479A priority Critical patent/GB2193725A/en
Publication of GB8606479D0 publication Critical patent/GB8606479D0/en
Priority to EP87302282A priority patent/EP0238313A1/en
Priority to PCT/GB1987/000184 priority patent/WO1987005623A1/en
Priority to JP50180287A priority patent/JPS63502797A/en
Publication of GB2193725A publication Critical patent/GB2193725A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/14Incubators; Climatic chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices

Description

GB2193725A 1 SPECIFICATION door is preferably insulated for example with
glass reinforced plastics material. Holes may Incubator be provided in the heating element to allow apparatus to be attached to the surface on This invention relates to an incubator or oven 70 which the heating element is to be mounted.
for a heated environment with a substantially The temperature of the incubator or oven uniform temperature throughout. Such incuba- may be displayed on a control panel. Control tors are used, for example, for growing culture circuits may be used to maintain the housing samples where it is required to maintain the cavity at a set temperature. A common oper cultures in an environment which is stable 75 ating temperature for incubators is 37'C but with regard to, for example temperature and higher temperatures may be used in an oven or atmosphere. or for example temperatures up to about A conventional incubator comprises a hous- 130'C for sterilization of an incubator.
ing surrounded by a water jacket. Water can A fan mounted on one of the inner walls be heated to a controlled temperature by 80 may be used to circulate the air in the incuba means of heating coils and circulated through tor.
the jacket to heat the incubator. This form of A humidity reservoir may be provided in the incubator is bulky because of the water jacket. base of the incubator compartment.
The apparatus is expensive and difficult to One or more gas inlets may be provided move because of the weight of water in the 85 through the housing, for example for C02, to jacket. help maintain a stable environment. The level Incubators are also manufactured which of a given gas and temperature may be moni- have electrical heating elements but the heat tored using sensors set on the inside of the output of such elements is concentrated into a compartment. It is preferable to have a good relatively small area of the wall. This tends to 90 airtight seal on the doors especially if the cul create an uneven temperature environment tures are to be kept, for example, in a C02 within the chamber compared with either a atmosphere.
water jacketed unit or the present invention. An embodiment of the invention is de- The present invention provides an incubator scribed below with reference to the drawings.
or oven comprising an insulated housing, the 95 Figure 1 shows a front elevation of the walls of which are lined with foil track electriapparatus in accordance with the invention; cal heating elements, and a thermostat for Figure 2 is a left hand side elevation; controlling the supply of electricity to the Figure 3 is a right hand side elevation; heating elements according to the temperature Figure 4 is a cross-section on the line A-A in the incubator. 100 of Fig. 1 on an enlarged scale; Such an incubator provides a cheap and Figure 5 is a cross-section on the line B-B convenient way of creating a stable environ- of Fig. 1 on an enlarged scale; ment for culture samples. The humidity and/or Figure 6 is a plan of the foil track heating composition of the atmosphere in the housing element designed for use in the apparatus.
may be regulated as well as its temperature. 105 The apparatus comprises a rectangular hous- By dispensing with a water jacket the cost ing 1 made up of five insulated walls 2 which and weight of the incubator can be substan- form the top, bottom, back and sides of the tially reduced. housing. The sixth wall at the front of the An additional advantage of even heat distri- housing is formed by an inner door 3 and an bution is that there is less tendency for con- 110 outer insulated door 4. An instrument unit 5 is densation to occur on the chamber walls at attached to one of the side walls. A motor 6 the high humidity normally found in this type connected to two fans 7 and 8 is mounted of incubator chamber. against an outer wall of the housing within the The foil track heating elements may each be instrument unit. The fan 7 is outside the hous- in the form of a sheet consisting of metallic 115 ing and serves to cool the motor. The fan 8 foil strip with a meandering path sandwiched is inside the housing and serves to circulate between layers of electrically insulating ma- the atmosphere in the housing.
terial, for example of mylar polyester. There The housing is constructed from two shells may be several alternating layers of insulating 9 of sheet metal pop- rivetted together at their material and metallic conductive material. The 120 edges.The space between the shells is insu metallic foil strip is preferably distributed in lated with slabs of glass fibre insulating ma such a manner so as to assist in attaining a terial 10. A silicone seal 11 runs around the uniform temperature throughout the incubator opening at the front of the housing and is or oven cavity, such a distribution may require fixed to the shells 9. This silicone seal forms a variation in concentration of metallic foil 125 an airtight seal with the inner door 3 when strip across a particular sheet. The foil track the door is closed.
heating elements may be self adhesive for A base plate 12 is attached by screws 13 mounting on the inner walls and may also be to the underside of the housing. Four feet 14 mounted on the outer door. A separate ele- with screw adjustments are secured to the ment sheet may be used for each wall. The 130 plate 12.
2 GB2193725A 2 The inner door 3 is made from a 14 mm the narrow region 54 approximately four times double glazed unit in an extruded PVC frame the density in the adjacent narrow region 55 and mounted by hinges 16 to the housing. which in turn is about one and a half times The inner door is provided with a door catch the density in the remainder of the blanket.
22, a catch retaining element 23 is mounted 70 Thus, in a particular example, the foil ele- on one of the side walls of the housing. ment is distributed within the blanket in the The outer door 4 is constructed from outer following manner:
and inner shells pop-rivetted together with in- 30% of the element is distributed evenly sulation of glass reinforced plastics material over an area 54 of 40mm x 544mm 25 in the space between the two shells. The 75 60% of the element is distributed evenly outer door is mounted on pivots 26 on brack- over an area 55 of 454mmx544mrn ets 27 attached to one of the side walls of 10% of the element is distributed over an the housing compartment. A magnetic catch area 56 of 5Ommx544mm and decreasing in 28 is provided on the outer shell of the corn- density from the junction with the high density partment with a corresponding retaining ele- 80 area 54 towards the lower element density ment 29 in the outer door. Silicone seals are area 55.
held at the junction of the outer and inner The variations in foil density compensate for shells of the door; these form an airtight seal variations in heat loss from different parts of with the outer shell of the walls when both the incubator. The heat loss tends to be doors are closed. The outer door is recessed 85 greater towards the glass inner door. The ele to accommodate the catch and catch retaining ment shown in Fig. 6 is designed for the four element for the inner door. walls adjacent the glass door. The element on A proximity switch 31 is provided to the the rear wall is designed with a high density inner door 3 which turns off the motor for the area closest to the fan storage where the ex fan when the inner door is opened. 90 tra heat is conducted away.
The inner walls of both the housing and the On the inner shell walls of the housing are outer door are each covered with foil track mounted brackets for nylon shelf spacers 33 heating elements 32. One sheet or blanket of by which runners 34 are held. Shelves 35 are foil track element is used for each wall. supported by the runners. The shelves are An example of a heating blanket is shown 95 stainless steel baffle plates with a rectangular in Fig. 6. array of circular holes.
The heating blanket 50 is made of two On the inner surface of the roof of the layers of myiar polyester 60 interleaved with a housing are mounted a gas sensor (C02) 36 distributed foil element. The elements are con- and a temperature sensor 37. These sensors nected in series to a 220/240 volt supply and 100 are connected by wires to control circuits 38 consumes about 100 watts. on the instrument unit. A humidity reservoir One side of the blanket has a self adhesive 41 is provided in the base of the housing.
coating. The self adhesive coating is for The instrument unit 5 mounted beside the mounting the blanket on the wall or door of housing, contains a control panel 39 for set the incubator. The adhesive used is stable up 105 ting the temperature and C02 level. The con to at least 13WC. trol panel then displays the actual temperature Holes 51 are provided in the blanket at and C02 levels by means of the sensors in the places which correspond to protruding sup- housing and the control circuit switches on ports, instruments etc. on the wall of the and off the current to the heating blankets or main cavity. The foil element extends as close 110 the gas flow to achieve and maintain a stable as possible to the edges of the holes while environment.
maintaining a safe margin for electrical insula- The instrument unit also contains a gas feed tion. 40 from an external source. This allows pure An element-free margin 52 is also left - C02 to be fed into the housing.
around the edge of the blanket for electrical 115

Claims (8)

  1. safety. CLAIMS
    The element is provided with terminals 53 1. An incubator or oven comprising an in- for connection to the power supply and con- sulated housing, the wall of which are lined trols housed in the instrument unit. with foil track electrical heating elements, and In Fig. 6 part of the top layer 60 of myiar 120 a temperature sensor for controlling the supply polyester has been removed to show part of of electricity to the heating elements according the foil element 61. The foil element consists to the temperature in the incubator.
    of a strip of metallic foil of uniform width
  2. 2. An incubator or oven according to claim which follows a meandering path across the 1 in which the walls of the housing comprise blanket. Both ends of the strip terminate at 125 outer and inner shells with insulating material the terminals 53. The spacing between adja- contained between them.
    cent sections of the strip is different in differ- 3. An incubator or oven according to claim ent parts of the blanket so that the heat out- 1 or 2 in which the housing has a door and put varies across the blanket. In the embodi- foil track heating element is mounted on the ment the density of the foil track strip is in 130 inside of the door.
  3. 3 GB2193725A 3
  4. 4. An incubator or oven according to any preceding claim in which the housing has a door comprising inner and outer shells with insulating material contained between the shells.
  5. 5. An incubator or oven according to claims 3 or 4 which is provided with an inner door of transparent material adjacent to the inside of the door of the housing.
  6. 6. An incubator or oven according to any of the preceding claims in which the housing is rectangular and has a door forming at least part of one wall of the housing, the other five walls of the housing all being lined with foil track heat elements.
  7. 7. An incubator substantially as hereinbe- fore described with reference to the accom panying Figs. 1 to 5.
  8. 8. An incubator substantially as hereinbe- fore described with reference to the drawings, at least one of the walls being lined with the heating element of Fig. 6.
    Published 1988 atThe Patent Office, State House, 66/71 High Holborn, London WC1 R 4TP. Further copies may be obtained from The Patent Office, Sales Branch, St Mary Cray, Orpington, Kent BR5 3RD.
    Printed by Burgess & Son (Abingdon) Ltd. Con. 1/87.
GB08606479A 1986-03-17 1986-03-17 Incubator Withdrawn GB2193725A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB08606479A GB2193725A (en) 1986-03-17 1986-03-17 Incubator
EP87302282A EP0238313A1 (en) 1986-03-17 1987-03-17 Incubator
PCT/GB1987/000184 WO1987005623A1 (en) 1986-03-17 1987-03-17 Incubator
JP50180287A JPS63502797A (en) 1986-03-17 1987-03-17 incubator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08606479A GB2193725A (en) 1986-03-17 1986-03-17 Incubator

Publications (2)

Publication Number Publication Date
GB8606479D0 GB8606479D0 (en) 1986-04-23
GB2193725A true GB2193725A (en) 1988-02-17

Family

ID=10594717

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08606479A Withdrawn GB2193725A (en) 1986-03-17 1986-03-17 Incubator

Country Status (4)

Country Link
EP (1) EP0238313A1 (en)
JP (1) JPS63502797A (en)
GB (1) GB2193725A (en)
WO (1) WO1987005623A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210039082A1 (en) * 2018-03-16 2021-02-11 Eppendorf Ag Laboratory cabinet device for storing laboratory samples, comprising a magnetic closure

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3815528C1 (en) * 1988-05-06 1989-08-10 W.C. Heraeus Gmbh, 6450 Hanau, De
JPH033436U (en) * 1989-05-30 1991-01-14
KR100236506B1 (en) * 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 Apparatus for polymerase chain reaction
FI89563C (en) * 1990-12-04 1993-10-25 P Antti Manninen EL-UPPVAERMT REAKTIONSKAERL
AT403550B (en) * 1992-08-18 1998-03-25 Robocon Lab Ind Roboter INCUBATOR
AT401476B (en) * 1993-08-20 1996-09-25 Sy Lab Vertriebsges M B H THERMAL CHAMBER
DE4440536C2 (en) * 1994-11-12 1999-11-25 Binder Peter Michael Incubator
FR2774392A1 (en) * 1998-02-05 1999-08-06 Pierre Yves Montfajon Micro biological sample incubator used in place where sample is taken
JP2000300243A (en) * 1999-04-23 2000-10-31 Sanyo Electric Co Ltd Box body in chamber of constant humidity device
US6365367B1 (en) 1999-12-06 2002-04-02 Cellomics, Inc. Environmental chamber for the analysis of live cells
DE102013009136A1 (en) * 2013-05-31 2014-12-04 SunChrom GmbH lnkubationskammer
CA3078231A1 (en) * 2017-10-06 2019-04-11 SeLux Diagnostics, Inc. Devices, systems, and methods for microbial incubation
EP3539419A1 (en) 2018-03-16 2019-09-18 Eppendorf AG Laboratory cabinet for storing laboratory samples with magnetic closure

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB963734A (en) * 1959-08-01 1964-07-15 Emils Gailis Incubators
GB1020311A (en) * 1961-01-20 1966-02-16 Eisler Paul Electrical heating film
GB1210904A (en) * 1968-03-22 1970-11-04 Aaron J Fink Temperature control chamber
GB2086421A (en) * 1980-09-15 1982-05-12 Lunaire Environmental Inc Laboratory incubator chamber system
EP0117001A1 (en) * 1983-02-22 1984-08-29 Carbolite Furnaces Limited Heating panels

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386792A (en) * 1971-04-08 1975-03-12 Rotax Ltd Electrical heating apparatus for reducing or preventing the formation of ice on aircraft parts
US3783238A (en) * 1972-11-08 1974-01-01 Armstrong Cork Co Electric curing oven
AT348632B (en) * 1976-09-21 1979-02-26 Koegler Adalbert SURFACE HEATING ELEMENT AND PROCESS FOR ITS MANUFACTURING
US4572427A (en) * 1984-03-02 1986-02-25 Mallinckrodt, Inc. Controlled atmosphere enclosure

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB963734A (en) * 1959-08-01 1964-07-15 Emils Gailis Incubators
GB1020311A (en) * 1961-01-20 1966-02-16 Eisler Paul Electrical heating film
GB1210904A (en) * 1968-03-22 1970-11-04 Aaron J Fink Temperature control chamber
GB2086421A (en) * 1980-09-15 1982-05-12 Lunaire Environmental Inc Laboratory incubator chamber system
EP0117001A1 (en) * 1983-02-22 1984-08-29 Carbolite Furnaces Limited Heating panels

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210039082A1 (en) * 2018-03-16 2021-02-11 Eppendorf Ag Laboratory cabinet device for storing laboratory samples, comprising a magnetic closure
US11951468B2 (en) * 2018-03-16 2024-04-09 Eppendorf Se Laboratory cabinet device for storing laboratory samples, comprising a magnetic closure

Also Published As

Publication number Publication date
GB8606479D0 (en) 1986-04-23
JPS63502797A (en) 1988-10-20
EP0238313A1 (en) 1987-09-23
WO1987005623A1 (en) 1987-09-24

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