GB2172812B - Chromatographic separation medium for rapid analysis of small samples - Google Patents

Chromatographic separation medium for rapid analysis of small samples

Info

Publication number
GB2172812B
GB2172812B GB08607241A GB8607241A GB2172812B GB 2172812 B GB2172812 B GB 2172812B GB 08607241 A GB08607241 A GB 08607241A GB 8607241 A GB8607241 A GB 8607241A GB 2172812 B GB2172812 B GB 2172812B
Authority
GB
United Kingdom
Prior art keywords
chromatographic separation
separation medium
small samples
rapid analysis
rapid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08607241A
Other versions
GB8607241D0 (en
GB2172812A (en
Inventor
David J Burke
Gary S Ott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of GB8607241D0 publication Critical patent/GB8607241D0/en
Publication of GB2172812A publication Critical patent/GB2172812A/en
Application granted granted Critical
Publication of GB2172812B publication Critical patent/GB2172812B/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3847—Multimodal interactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Peptides Or Proteins (AREA)
GB08607241A 1985-03-25 1986-03-24 Chromatographic separation medium for rapid analysis of small samples Expired GB2172812B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71584285A 1985-03-25 1985-03-25

Publications (3)

Publication Number Publication Date
GB8607241D0 GB8607241D0 (en) 1986-04-30
GB2172812A GB2172812A (en) 1986-10-01
GB2172812B true GB2172812B (en) 1989-01-11

Family

ID=24875696

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08607241A Expired GB2172812B (en) 1985-03-25 1986-03-24 Chromatographic separation medium for rapid analysis of small samples

Country Status (4)

Country Link
JP (1) JPS61257236A (en)
CA (1) CA1265116A (en)
DE (1) DE3609021A1 (en)
GB (1) GB2172812B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009832A1 (en) * 1989-02-21 1990-09-07 Eastman Kodak Company High performance affinity chromatography column comprising non-porous, monodisperse polymeric packing material
JP2619537B2 (en) * 1989-09-18 1997-06-11 株式会社日立製作所 Liquid chromatography method, apparatus, system, and separation column
DE19962577A1 (en) 1999-12-23 2001-07-12 Tittgen Biotechnologie Dr Chromatography material and method using the same
US20020164644A1 (en) * 2000-04-05 2002-11-07 Ikuro Maruyama Adsorbents for high mobility group proteins and column for purifying body fluid
CN101370536A (en) 2005-12-13 2009-02-18 埃克塞拉有限责任公司 Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
WO2008155683A1 (en) 2007-06-18 2008-12-24 Firmenich Sa Malodor counteracting compositions and method for their use
EP2509604B1 (en) 2009-12-01 2021-03-17 ExThera Medical Corporation Device for removing cytokines from blood with surface immobilized polysaccharides
JP5812463B2 (en) * 2010-07-01 2015-11-11 積水メディカル株式会社 Method for separation and detection of nucleic acids by liquid chromatography
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
FI20115816L (en) * 2011-08-22 2013-02-23 Silverphase Oy Antimicrobial ionomer composition and its applications
ES2647577T3 (en) 2012-06-13 2017-12-22 Exthera Medical Corporation Use of heparin and carbohydrates to treat cancer
BR112015032134B1 (en) 2013-06-24 2022-05-10 Exthera Medical Corporation Method of end-linking a non-reducing mannose to a substrate and bead having an end-linked mannose
ES2799398T3 (en) 2013-11-08 2020-12-17 Exthera Medical Corp Methods for diagnosing infectious diseases using adsorption media
KR20170020749A (en) 2014-04-24 2017-02-24 엑스테라 메디컬 코퍼레이션 Method for removing bacteria from blood using high flow rate
JP7100454B2 (en) 2014-09-22 2022-07-13 エクスセラ メディカル コーポレイション Wearable blood perfusion device
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
US10786615B2 (en) 2016-03-02 2020-09-29 Exthera Medical Corporation Method for treating drug intoxication
JP6757598B2 (en) * 2016-05-27 2020-09-23 日立化成テクノサービス株式会社 Separator and column
US20220219139A1 (en) * 2019-05-09 2022-07-14 Showa Denko Materials Co., Ltd. Adsorbent particles, method for producing adsorbent particles, base material particles, filling column and method for recovering rare earth element
JP2022534191A (en) 2019-05-16 2022-07-28 エクスセラ メディカル コーポレイション Methods for modulating endothelial glycocalyx
JP7476894B2 (en) * 2019-06-13 2024-05-01 株式会社レゾナック Adsorbent particles, substrate particles, packed column, and method for recovering rare earth elements

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE357622B (en) * 1969-12-22 1973-07-02 Exploaterings Ab Tbf
DE2225973C2 (en) * 1972-05-27 1974-07-04 Merck Patent Gmbh, 6100 Darmstadt Process for coating non-porous material with a porous silicon dioxide layer
CS159990B1 (en) * 1972-08-30 1975-02-28
GB1526869A (en) * 1975-07-24 1978-10-04 Grace C Automatic data processing system
JPS52150093A (en) * 1976-06-07 1977-12-13 Sekisui Chemical Co Ltd Hydrophiltc filler for liquid chromatograph
CS188619B1 (en) * 1977-01-19 1979-03-30 Jaromir Lukas Polar polymere sorbent based on glycidylic esters for gas and liquid chromatography
JPS54103396A (en) * 1978-01-31 1979-08-14 Sekisui Chemical Co Ltd Bulking agent for liquid chromatograph
JPS5845658B2 (en) * 1979-01-24 1983-10-12 積水化学工業株式会社 Packing material for liquid chromatography
EP0021817B1 (en) * 1979-06-22 1985-10-02 Sekisui Kagaku Kogyo Kabushiki Kaisha Filler for liquid chromatography, method for separating water-soluble substances using said filler and use of said filler in separating water-soluble biochemical substances
US4384954A (en) * 1980-04-16 1983-05-24 Kuraray Co., Ltd. Column for adsorption of blood proteins
US4468330A (en) * 1981-04-27 1984-08-28 Sekisui Kagaku Kogyo Kabushiki Kaisha Filler for liquid chromatography useful for separating a hemoglobin variant in blood

Also Published As

Publication number Publication date
GB8607241D0 (en) 1986-04-30
GB2172812A (en) 1986-10-01
CA1265116A (en) 1990-01-30
JPS61257236A (en) 1986-11-14
DE3609021A1 (en) 1986-09-25

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950324